Ashley Hughes
Ashley Hughes
Rutherford International Fellow, Diamond Light Source
Verified email at
Cited by
Cited by
Heparan sulfate and heparin interactions with proteins
MCZ Meneghetti, AJ Hughes, TR Rudd, HB Nader, AK Powell, EA Yates, ...
Journal of the Royal Society Interface 12 (110), 20150589, 2015
Structural photoactivation of a full-length bacterial phytochrome
A Björling, O Berntsson, H Lehtivuori, H Takala, AJ Hughes, M Panman, ...
Science advances 2 (8), e1600920, 2016
Sequential conformational transitions and α-helical supercoiling regulate a sensor histidine kinase
O Berntsson, RP Diensthuber, MR Panman, A Björling, E Gustavsson, ...
Nature communications 8 (1), 1-8, 2017
Chemically modified, non-anticoagulant heparin derivatives are potent galectin-3 binding inhibitors and inhibit circulating galectin-3-promoted metastasis
CA Duckworth, SE Guimond, P Sindrewicz, AJ Hughes, NS French, ...
Oncotarget 6 (27), 23671, 2015
Analysis of the fibroblast growth factor receptor (FGFR) signalling network with heparin as coreceptor: evidence for the expansion of the core FGFR signalling network
R Xu, TR Rudd, AJ Hughes, G Siligardi, DG Fernig, EA Yates
The FEBS journal 280 (10), 2260-2270, 2013
A non-hemorrhagic hybrid heparin/heparan sulfate with anticoagulant potential
AS Brito, RS Cavalcante, LCGF Palhares, AJ Hughes, GPV Andrade, ...
Carbohydrate polymers 99, 372-378, 2014
On the (un) coupling of the chromophore, tongue interactions, and overall conformation in a bacterial phytochrome
H Takala, HK Lehtivuori, O Berntsson, A Hughes, R Nanekar, S Niebling, ...
Journal of Biological Chemistry 293 (21), 8161-8172, 2018
Time-resolved X-ray solution scattering reveals the structural photoactivation of a light-oxygen-voltage photoreceptor
O Berntsson, RP Diensthuber, MR Panman, A Björling, AJ Hughes, ...
Structure 25 (6), 933-938. e3, 2017
Antithrombin stabilisation by sulfated carbohydrates correlates with anticoagulant activity
MA Lima, AJ Hughes, N Veraldi, TR Rudd, R Hussain, AS Brito, ...
MedChemComm 4 (5), 870-873, 2013
Heparin derivatives for the targeting of multiple activities in the inflammatory response
N Veraldi, AJ Hughes, TR Rudd, HB Thomas, SW Edwards, L Hadfield, ...
Carbohydrate polymers 117, 400-407, 2015
Photoactivation of Drosophila melanogaster cryptochrome through sequential conformational transitions
O Berntsson, R Rodriguez, L Henry, MR Panman, AJ Hughes, C Einholz, ...
Science advances 5 (7), eaaw1531, 2019
A zinc complex of heparan sulfate destabilises lysozyme and alters its conformation
AJ Hughes, R Hussain, C Cosentino, M Guerrini, G Siligardi, EA Yates, ...
Biochemical and biophysical research communications 425 (4), 794-799, 2012
Assessing the ability of spectroscopic methods to determine the difference in the folding propensities of highly similar β-hairpins
H Andersson, E Danelius, P Jarvoll, S Niebling, AJ Hughes, S Westenhoff, ...
ACS omega 2 (2), 508-516, 2017
Heparan sulphate, its derivatives and analogues share structural characteristics that can be exploited, particularly in inhibiting microbial attachment
TR Rudd, A Hughes, J Holman, V Solari, E de Oliveira Ferreira, ...
Brazilian Journal of Medical and Biological Research 45 (5), 386-391, 2012
Investigating the relationship between temperature, conformation and calcium binding in heparin model oligosaccharides
A Hughes, M Meneghetti, TY Huang, SC Hung, S Elli, M Guerrini, T Rudd, ...
Carbohydrate research 438, 58-64, 2017
Observing the structural evolution in the photodissociation of diiodomethane with femtosecond solution x-ray scattering
MR Panman, E Biasin, O Berntsson, M Hermann, S Niebling, AJ Hughes, ...
Physical Review Letters 125 (22), 226001, 2020
New Light on the Mechanism of Phototransduction in Phototropin
L Henry, O Berntsson, MR Panman, A Cellini, AJ Hughes, I Kosheleva, ...
Biochemistry 59 (35), 3206-3215, 2020
Detection of interaction between protein trytophan residues and small or macromolecular ligands by synchrotron radiation magnetic circular dichroism
AJ Hughes, TR Rudd, GSA Wright, DG Fernig, G Siligardi, EA Yates
Analytical Methods 7 (5), 1667-1671, 2015
Light induced charge and energy transport in nucleic acids and proteins: general discussion
A Chattopadhyay, R Cogdell, CE Crespo-Hernández, A Datta, A De, ...
Faraday discussions 207, 153-180, 2018
Mr Alfy Benny, IISER Thiruvananthapuram, India Mr Vinayak Bhat, IISER Thiruvananthapuram, India Mr Amarnath Bollu, National Institute of Science Education and Research (NISER …
MJ Busby, MA Chandra, A Chattopadhyay, R Cogdell, ...
Faraday Discuss 207, 525-526, 2018
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