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Heng-Huan Lee
Heng-Huan Lee
Postdoctoral Fellow of Biomedical Science, MD Anderson Cancer Center
Verified email at mdanderson.org
Title
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Cited by
Year
p53 regulates epithelial–mesenchymal transition and stem cell properties through modulating miRNAs
CJ Chang, CH Chao, W Xia, JY Yang, Y Xiong, CW Li, WH Yu, ...
Nature cell biology 13 (3), 317-323, 2011
8712011
Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity
CW Li, SO Lim, W Xia, HH Lee, LC Chan, CW Kuo, KH Khoo, SS Chang, ...
Nature communications 7 (1), 12632, 2016
8592016
PARP inhibitor upregulates PD-L1 expression and enhances cancer-associated immunosuppression
S Jiao, W Xia, H Yamaguchi, Y Wei, MK Chen, JM Hsu, JL Hsu, WH Yu, ...
Clinical Cancer Research 23 (14), 3711-3720, 2017
8362017
Metformin promotes antitumor immunity via endoplasmic-reticulum-associated degradation of PD-L1
JH Cha, WH Yang, W Xia, Y Wei, LC Chan, SO Lim, CW Li, T Kim, ...
Molecular cell 71 (4), 606-620. e7, 2018
5522018
Eradication of triple-negative breast cancer cells by targeting glycosylated PD-L1
CW Li, SO Lim, EM Chung, YS Kim, AH Park, J Yao, JH Cha, W Xia, ...
Cancer cell 33 (2), 187-201. e10, 2018
4522018
Removal of N-linked glycosylation enhances PD-L1 detection and predicts anti-PD-1/PD-L1 therapeutic efficacy
HH Lee, YN Wang, W Xia, CH Chen, KM Rau, L Ye, Y Wei, CK Chou, ...
Cancer cell 36 (2), 168-178. e4, 2019
2632019
IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion
LC Chan, CW Li, W Xia, JM Hsu, HH Lee, JH Cha, HL Wang, WH Yang, ...
The Journal of clinical investigation 129 (8), 3324-3338, 2019
2402019
EGFR Signaling Enhances Aerobic Glycolysis in Triple-Negative Breast Cancer Cells to Promote Tumor Growth and Immune Escape
HMC Lim SO, Li CW, Xia W, Lee HH, Chang SS, Shen J, Hsu JL, Raftery D ...
Cancer Research 76, 1284-1296, 2016
2322016
COPI-mediated retrograde trafficking from the Golgi to the ER regulates EGFR nuclear transport
YN Wang, H Wang, H Yamaguchi, HJ Lee, HH Lee, MC Hung
Biochemical and biophysical research communications 399 (4), 498-504, 2010
1672010
p53 acetylation is crucial for its transcription-independent proapoptotic functions
H Yamaguchi, NT Woods, LG Piluso, HH Lee, J Chen, KN Bhalla, ...
Journal of Biological Chemistry 284 (17), 11171-11183, 2009
1522009
TYRO3 induces anti–PD-1/PD-L1 therapy resistance by limiting innate immunity and tumoral ferroptosis
Z Jiang, SO Lim, M Yan, JL Hsu, J Yao, Y Wei, SS Chang, H Yamaguchi, ...
The Journal of clinical investigation 131 (8), 2021
1502021
The translocon Sec61β localized in the inner nuclear membrane transports membrane-embedded EGF receptor to the nucleus
YN Wang, H Yamaguchi, L Huo, Y Du, HJ Lee, HH Lee, H Wang, JM Hsu, ...
Journal of Biological Chemistry 285 (49), 38720-38729, 2010
1392010
PRMT1-mediated methylation of the EGF receptor regulates signaling and cetuximab response.
HMC Liao HW, Hsu JM, Xia W, Wang HL, Wang YN, Chang WC, Arold ST, Chou CK ...
The Journal of Clinical Investigation 125, 4529-4543, 2015
1292015
The impact of PD-L1 N-linked glycosylation on cancer therapy and clinical diagnosis
YN Wang, HH Lee, JL Hsu, D Yu, MC Hung
Journal of biomedical science 27, 1-11, 2020
1042020
Targeting glycosylated PD-1 induces potent antitumor immunity
L Sun, CW Li, EM Chung, R Yang, YS Kim, AH Park, YJ Lai, Y Yang, ...
Cancer research 80 (11), 2298-2310, 2020
1002020
Small-molecule MMP2/MMP9 inhibitor SB-3CT modulates tumor immune surveillance by regulating PD-L1
Y Ye, X Kuang, Z Xie, L Liang, Z Zhang, Y Zhang, F Ma, Q Gao, R Chang, ...
Genome medicine 12, 1-19, 2020
962020
Membrane-bound trafficking regulates nuclear transport of integral epidermal growth factor receptor (EGFR) and ErbB-2
YN Wang, HH Lee, HJ Lee, Y Du, H Yamaguchi, MC Hung
Journal of Biological Chemistry 287 (20), 16869-16879, 2012
962012
Induction of the early growth response 1 gene by Epstein-Barr virus lytic transactivator Zta
Y Chang, HH Lee, YT Chen, J Lu, SY Wu, CW Chen, K Takada, CH Tsai
Journal of virology 80 (15), 7748-7755, 2006
782006
Epidermal growth factor receptor potentiates MCM7-mediated DNA replication through tyrosine phosphorylation of Lyn kinase in human cancers
TH Huang, L Huo, YN Wang, W Xia, Y Wei, SS Chang, WC Chang, ...
Cancer cell 23 (6), 796-810, 2013
692013
Angiogenin/ribonuclease 5 is an EGFR ligand and a serum biomarker for erlotinib sensitivity in pancreatic cancer
YN Wang, HH Lee, CK Chou, WH Yang, Y Wei, CT Chen, J Yao, JL Hsu, ...
Cancer Cell 33 (4), 752-769. e8, 2018
672018
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