WNT16 antagonises excessive canonical WNT activation and protects cartilage in osteoarthritis G Nalesso, BL Thomas, JC Sherwood, J Yu, O Addimanda, SE Eldridge, ... Annals of the rheumatic diseases 76 (1), 218-226, 2017 | 126 | 2017 |
Agrin mediates chondrocyte homeostasis and requires both LRP4 and α-dystroglycan to enhance cartilage formation in vitro and in vivo S Eldridge, G Nalesso, H Ismail, K Vicente-Greco, P Kabouridis, ... Annals of the rheumatic diseases 75 (6), 1228-1235, 2016 | 58 | 2016 |
MMP-3 in the peripheral serum as a biomarker of knee osteoarthritis, 40 years after open total knee meniscectomy I Pengas, S Eldridge, A Assiotis, M McNicholas, JE Mendes, L Laver Journal of experimental orthopaedics 5, 1-8, 2018 | 53 | 2018 |
Cellular and molecular mechanisms of cartilage damage and repair JC Sherwood, J Bertrand, SE Eldridge, F Dell’Accio Drug discovery today 19 (8), 1172-1177, 2014 | 53 | 2014 |
ROR2 blockade as a therapy for osteoarthritis AS Thorup, D Strachan, S Caxaria, B Poulet, BL Thomas, SE Eldridge, ... Science translational medicine 12 (561), eaax3063, 2020 | 47 | 2020 |
Agrin induces long-term osteochondral regeneration by supporting repair morphogenesis SE Eldridge, A Barawi, H Wang, AJ Roelofs, M Kaneva, Z Guan, H Lydon, ... Science translational medicine 12 (559), eaax9086, 2020 | 34 | 2020 |
WNT3A‐loaded exosomes enable cartilage repair BL Thomas, SE Eldridge, B Nosrati, M Alvarez, AS Thorup, G Nalesso, ... Journal of extracellular vesicles 10 (7), e12088, 2021 | 31 | 2021 |
Calcium calmodulin kinase II activity is required for cartilage homeostasis in osteoarthritis G Nalesso, AS Thorup, SE Eldridge, A De Palma, A Kaur, K Peddireddi, ... Scientific reports 11 (1), 5682, 2021 | 15 | 2021 |
Lessons from joint development for cartilage repair in the clinic AS Thorup, F Dell'Accio, SE Eldridge Developmental Dynamics 250 (3), 360-376, 2021 | 6 | 2021 |
Disease modification and symptom relief in osteoarthritis using a mutated GCP‐2/CXCL6 chemokine S Caxaria, N Kouvatsos, SE Eldridge, M Alvarez‐Fallas, AS Thorup, ... EMBO Molecular Medicine 15 (1), e16218, 2023 | 5 | 2023 |
Wnt5a/CaMKII pathway is activated in osteoarthritis and promotes loss of chondrocyte phenotype G Nalesso, BL Thomas, SE Eldridge, K Wagner, J Sherwood, J Bertrand, ... Osteoarthritis and Cartilage 21, S226, 2013 | 4 | 2013 |
In vivo potency assay for the screening of bioactive molecules on cartilage formation AS Thorup, S Caxaria, BL Thomas, Y Suleman, G Nalesso, FP Luyten, ... Lab animal 51 (4), 103-120, 2022 | 3 | 2022 |
A potency assay for assessing the chondrogenic efficiency of bioactive molecules in human cartilage in vivo AS Thorup, SE Eldridge, S Caxaria, G Nalesso, BL Thomas, C Pitzalis, ... Osteoarthritis and Cartilage 25, S273, 2017 | 3 | 2017 |
Pharmacological blockade of CAMKII is detrimental for osteoarthritis progression G Nalesso, K Wagner, J Bertrand, JC Sherwood, BL Thomas, SE Eldridge, ... Osteoarthritis and Cartilage 24, S149, 2016 | 3 | 2016 |
MMP3 cleaves agrin in cartilage and reduces its chondrogenic potency SE Eldridge, E Petrycki, C Pitzalis, J Whiteford, F Dell'Accio Osteoarthritis and Cartilage 24, S379, 2016 | 2 | 2016 |
Short term il1ra treatment reduces post-traumatic OA in mouse in vivo and, in vitro, in human cartilage M Bollmann, H Brinkema, S Piatek, F Walcher, M Alvarez, S Eldridge, ... Osteoarthritis and Cartilage 28, S490, 2020 | 1 | 2020 |
The WNT/CaMKII pathway is activated in human and experimental osteoarthritis and promotes chondrocyte de-differentiation G Nalesso, B Thomas, K Wagner, J Bertrand, J Sherwood, S Eldridge, ... INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY 95 (3), A25-A26, 2014 | 1 | 2014 |
INTRA-ARTICULAR ADMINISTRATION OF AGRIN INDUCES RAPID AND SUSTAINED PAIN RELIEF IN OSTEOARTHRITIS F Dajas-Bailador, V Chapman, C Lucci, A Rathbone, S Bharde, ... Osteoarthritis and Cartilage 32, S52, 2024 | | 2024 |
A Mouse Model of Acute Cartilage Injury and Repair AS Thorup, F Dell’Accio, SE Eldridge Cartilage Tissue Engineering, 337-344, 2022 | | 2022 |
AB0156 INTRA-ARTICULAR AGRIN PROVIDES DIRECT PAIN RELIEF IN OSTEOARTHRITIS AND CARTILAGE DEFECTS S Eldridge, A Barawi, AS Thorup, BF Fernandez, S Bharde, S Sikandar, ... Annals of the Rheumatic Diseases 81 (Suppl 1), 1208-1208, 2022 | | 2022 |