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Rachael Natrajan
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Resistance to therapy caused by intragenic deletion in BRCA2
SL Edwards, R Brough, CJ Lord, R Natrajan, R Vatcheva, DA Levine, ...
Nature 451 (7182), 1111-1115, 2008
10832008
Complex landscapes of somatic rearrangement in human breast cancer genomes
PJ Stephens, DJ McBride, ML Lin, I Varela, ED Pleasance, JT Simpson, ...
Nature 462 (7276), 1005-1010, 2009
9962009
BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells
G Molyneux, FC Geyer, FA Magnay, A McCarthy, H Kendrick, R Natrajan, ...
Cell stem cell 7 (3), 403-417, 2010
8852010
FGFR1 amplification drives endocrine therapy resistance and is a therapeutic target in breast cancer
N Turner, A Pearson, R Sharpe, M Lambros, F Geyer, MA Lopez-Garcia, ...
Cancer research 70 (5), 2085-2094, 2010
8032010
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer
SA Eccles, EO Aboagye, S Ali, AS Anderson, J Armes, F Berditchevski, ...
Breast Cancer Research 15 (5), 1-37, 2013
5002013
Breast cancer molecular profiling with single sample predictors: a retrospective analysis
B Weigelt, A Mackay, R A'hern, R Natrajan, DSP Tan, M Dowsett, ...
The lancet oncology 11 (4), 339-349, 2010
4762010
Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets
N Turner, MB Lambros, HM Horlings, A Pearson, R Sharpe, R Natrajan, ...
Oncogene 29 (14), 2013-2023, 2010
4562010
β-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation
FC Geyer, M Lacroix-Triki, K Savage, M Arnedos, MB Lambros, A MacKay, ...
Modern pathology 24 (2), 209-231, 2011
4122011
PTEN deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to PARP inhibitors
KJ Dedes, D Wetterskog, AM Mendes-Pereira, R Natrajan, MB Lambros, ...
Science translational medicine 2 (53), 53ra75-53ra75, 2010
4012010
Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer
DR Robinson, S Kalyana-Sundaram, YM Wu, S Shankar, X Cao, B Ateeq, ...
Nature medicine 17 (12), 1646-1651, 2011
3982011
Genome-wide profiling of genetic synthetic lethality identifies CDK12 as a novel determinant of PARP1/2 inhibitor sensitivity
I Bajrami, JR Frankum, A Konde, RE Miller, FL Rehman, R Brough, ...
Cancer research 74 (1), 287-297, 2014
3592014
Identification of a disease-defining gene fusion in epithelioid hemangioendothelioma
MR Tanas, A Sboner, AM Oliveira, MR Erickson-Johnson, J Hespelt, ...
Science translational medicine 3 (98), 98ra82-98ra82, 2011
3532011
Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C
NH Dryden, LR Broome, F Dudbridge, N Johnson, N Orr, S Schoenfelder, ...
Genome research 24 (11), 1854-1868, 2014
2672014
SF3B1 mutations constitute a novel therapeutic target in breast cancer
SL Maguire, A Leonidou, P Wai, C Marchiò, CKY Ng, A Sapino, ...
The Journal of pathology 235 (4), 571-580, 2015
2372015
Molecular analysis reveals a genetic basis for the phenotypic diversity of metaplastic breast carcinomas
FC Geyer, B Weigelt, R Natrajan, MBK Lambros, D de Biase, R Vatcheva, ...
The Journal of Pathology: A Journal of the Pathological Society of Great …, 2010
2302010
Infant high-grade gliomas comprise multiple subgroups characterized by novel targetable gene fusions and favorable outcomes
M Clarke, A Mackay, B Ismer, JC Pickles, RG Tatevossian, S Newman, ...
Cancer discovery 10 (7), 942-963, 2020
1962020
Genomic and mutational profiling of ductal carcinomas in situ and matched adjacent invasive breast cancers reveals intra‐tumour genetic heterogeneity and clonal …
L Hernandez, PM Wilkerson, MB Lambros, A Campion‐Flora, ...
The Journal of pathology 227 (1), 42-52, 2012
1932012
FGFR Signaling Promotes the Growth of Triple-Negative and Basal-Like Breast Cancer Cell Lines Both In Vitro and In Vivo
R Sharpe, A Pearson, MT Herrera-Abreu, D Johnson, A Mackay, JC Welti, ...
Clinical Cancer Research 17 (16), 5275-5286, 2011
1922011
Mucinous carcinoma of the breast is genomically distinct from invasive ductal carcinomas of no special type
M Lacroix‐Triki, PH Suarez, A MacKay, MB Lambros, R Natrajan, ...
The Journal of pathology 222 (3), 282-298, 2010
1912010
Down-regulation of the miRNA master regulators Drosha and Dicer is associated with specific subgroups of breast cancer
KJ Dedes, R Natrajan, MB Lambros, FC Geyer, MA Lopez-Garcia, ...
European journal of cancer 47 (1), 138-150, 2011
1902011
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