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Ali Ryan
Ali Ryan
Verified email at northumbria.ac.uk - Homepage
Title
Cited by
Cited by
Year
Effect of detergent on “promiscuous” inhibitors
AJ Ryan, NM Gray, PN Lowe, C Chung
Journal of medicinal chemistry 46 (16), 3448-3451, 2003
2902003
Structural basis of binding of fluorescent, site-specific dansylated amino acids to human serum albumin
AJ Ryan, J Ghuman, PA Zunszain, C Chung, S Curry
Journal of Structural Biology 174 (1), 84-91, 2011
1632011
Arylamine N‐acetyltransferases: from drug metabolism and pharmacogenetics to drug discovery
E Sim, A Abuhammad, A Ryan
British Journal of Pharmacology 171 (11), 2705-2725, 2014
1602014
Azoreductases in drug metabolism
A Ryan
British Journal of Pharmacology 174 (14), 2161-2173, 2017
782017
A novel mechanism for azoreduction
A Ryan, N Laurieri, I Westwood, CJ Wang, E Lowe, E Sim
Journal of molecular biology 400 (1), 24-37, 2010
662010
Improvements in behaviour and physical manifestations in previously untreated adults with phenylketonuria using a phenylalanine‐restricted diet: a national survey
S Yannicelli, A Ryan
Journal of inherited metabolic disease 18 (2), 131-134, 1995
661995
Reaction mechanism of azoreductases suggests convergent evolution with quinone oxidoreductases
A Ryan, CJ Wang, N Laurieri, I Westwood, E Sim
Protein & cell 1, 780-790, 2010
622010
Identification of NAD (P) H quinone oxidoreductase activity in azoreductases from P. aeruginosa: azoreductases and NAD (P) H quinone oxidoreductases belong to the same FMN …
A Ryan, E Kaplan, JC Nebel, E Polycarpou, V Crescente, E Lowe, ...
PloS one 9 (6), e98551, 2014
61*2014
Activation of nitrofurazone by azoreductases: multiple activities in one enzyme
A Ryan, E Kaplan, N Laurieri, E Lowe, E Sim
Scientific Reports 1 (1), 63, 2011
492011
Extracorporeal enzyme reactors for depletion of phenylalanine in phenylketonuria
CM AMBRUS, S ANTHONE, C HORVATH, K KALGHATGI, AS LELE, ...
Annals of internal medicine 106 (4), 531-537, 1987
471987
Crystallographic analysis reveals the structural basis of the high-affinity binding of iophenoxic acid to human serum albumin
AJ Ryan, C Chung, S Curry
BMC structural biology 11, 1-7, 2011
402011
Primary sequence contribution to the optical function of the eye lens
K Mahendiran, C Elie, JC Nebel, A Ryan, BK Pierscionek
Scientific Reports 4 (1), 5195, 2014
362014
Role of tyrosine 131 in the active site of paAzoR1, an azoreductase with specificity for the inflammatory bowel disease prodrug balsalazide
CJ Wang, N Laurieri, A Abuhammad, E Lowe, I Westwood, A Ryan, E Sim
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2010
342010
Structure–activity relationships and colorimetric properties of specific probes for the putative cancer biomarker human arylamine N-acetyltransferase 1
JE Egleton, CC Thinnes, PT Seden, N Laurieri, SP Lee, KS Hadavizadeh, ...
Bioorganic & medicinal chemistry 22 (11), 3030-3054, 2014
272014
Anakinra for palmoplantar pustulosis: results from a randomized, double‐blind, multicentre, two‐staged, adaptive placebo‐controlled trial (APRICOT)
S Cro, VR Cornelius, AE Pink, R Wilson, A Pushpa‐Rajah, P Patel, ...
British Journal of Dermatology 186 (2), 245-256, 2022
242022
Identification of novel members of the bacterial azoreductase family in Pseudomonas aeruginosa
V Crescente, SM Holland, S Kashyap, E Polycarpou, E Sim, A Ryan
Biochemical Journal 473 (5), 549-558, 2016
232016
Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti‐tubercular agents using a fragment‐based drug design approach
A Ryan, E Polycarpou, NA Lack, D Evangelopoulos, C Sieg, A Halman, ...
British journal of pharmacology 174 (14), 2209-2224, 2017
222017
Comparative analysis of xenobiotic metabolising N-acetyltransferases from ten non-human primates as in vitro models of human homologues
T Tsirka, M Konstantopoulou, A Sabbagh, B Crouau-Roy, A Ryan, E Sim, ...
Scientific reports 8 (1), 9759, 2018
182018
The role of apolipoprotein N‐acyl transferase, Lnt, in the lipidation of factor H binding protein of Neisseria meningitidis strain MC58 and its potential as a drug target
RAG Da Silva, CP Churchward, AV Karlyshev, O Eleftheriadou, ...
British Journal of Pharmacology 174 (14), 2247-2260, 2017
172017
Potential use of the maillard reaction for pharmaceutical applications: Gastric and intestinal controlled release alginate-albumin beads
M Khoder, HK Gbormoi Sr, A Ryan, A Karam, RG Alany
Pharmaceutics 11 (2), 83, 2019
152019
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Articles 1–20