Dirk Fey
Title
Cited by
Cited by
Year
Crosstalk and signaling switches in mitogen-activated protein kinase cascades
D Fey, DR Croucher, W Kolch, BN Kholodenko
Frontiers in physiology 3, 355, 2012
1442012
Frequency modulation of ERK activation dynamics rewires cell fate
H Ryu, M Chung, M Dobrzyński, D Fey, Y Blum, SS Lee, M Peter, ...
Molecular systems biology 11 (11), 838, 2015
1362015
Signaling pathway models as biomarkers: Patient-specific simulations of JNK activity predict the survival of neuroblastoma patients
D Fey, M Halasz, D Dreidax, SP Kennedy, JF Hastings, N Rauch, ...
Science signaling 8 (408), ra130-ra130, 2015
1102015
Exact model reduction of combinatorial reaction networks
H Conzelmann, D Fey, ED Gilles
BMC systems biology 2 (1), 1-25, 2008
662008
The complexities and versatility of the RAS-to-ERK signalling system in normal and cancer cells
D Fey, D Matallanas, J Rauch, OS Rukhlenko, BN Kholodenko
Seminars in cell & developmental biology 58, 96-107, 2016
562016
Pseudophosphatase STYX modulates cell-fate decisions and cell migration by spatiotemporal regulation of ERK1/2
V Reiterer, D Fey, W Kolch, BN Kholodenko, H Farhan
Proceedings of the National Academy of Sciences 110 (31), E2934-E2943, 2013
432013
The extracellular matrix as a key regulator of intracellular signalling networks
JF Hastings, JN Skhinas, D Fey, DR Croucher, TR Cox
British journal of pharmacology 176 (1), 82-92, 2019
382019
PP1 initiates the dephosphorylation of MASTL, triggering mitotic exit and bistability in human cells
S Rogers, D Fey, RA McCloy, BL Parker, NJ Mitchell, RJ Payne, RJ Daly, ...
Journal of Cell Science 129 (7), 1340-1354, 2016
382016
Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma
DJ Duffy, A Krstic, M Halasz, T Schwarzl, D Fey, K Iljin, JP Mehta, K Killick, ...
Oncotarget 6 (41), 43182, 2015
282015
MASTL overexpression promotes chromosome instability and metastasis in breast cancer
S Rogers, RA McCloy, BL Parker, D Gallego-Ortega, AMK Law, VT Chin, ...
Oncogene 37 (33), 4518-4533, 2018
262018
Performance of objective functions and optimisation procedures for parameter estimation in system biology models
A Degasperi, D Fey, BN Kholodenko
NPJ systems biology and applications 3 (1), 1-9, 2017
242017
Parameter estimation in kinetic reaction models using nonlinear observers facilitated by model extensions
D Fey, R Findeisen, E Bullinger
Proc. 17th IFAC World Congres, Seoul, 313-318, 2008
242008
Wnt signalling is a bi-directional vulnerability of cancer cells
DJ Duffy, A Krstic, T Schwarzl, M Halasz, K Iljin, D Fey, B Haley, J Whilde, ...
Oncotarget 7 (37), 60310, 2016
232016
Polyubiquitin chain assembly and organization determine the dynamics of protein activation and degradation
LK Nguyen, M Dobrzynski, D Fey, BN Kholodenko
Frontiers in physiology 5, 4, 2014
232014
Quantitative biology: theory, computational methods, and models
B Munsky, WS Hlavacek, LS Tsimring
MIT Press, 2018
132018
Frequency modulation of ERK activation dynamics rewires cell fate
H Ryu, M Chung, M Dobrzyński, D Fey, Y Blum, S Sik Lee, M Peter, ...
Molecular systems biology 12 (4), 866, 2016
132016
Control of the G-protein cascade dynamics by GDP dissociation inhibitors
E Nikonova, MA Tsyganov, W Kolch, D Fey, BN Kholodenko
Molecular bioSystems 9 (10), 2454-2462, 2013
132013
Personalized computational models as biomarkers
W Kolch, D Fey
Journal of personalized medicine 7 (3), 9, 2017
102017
Hippocampal contribution to vector model hypothesis during cue-dependent navigation
M Diviney, D Fey, S Commins
Learning & Memory 20 (7), 367-378, 2013
92013
Limiting the parameter search space for dynamic models with rational kinetics using semi-definite programming
D Fey, E Bullinger
IFAC Proceedings Volumes 43 (6), 150-155, 2010
92010
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Articles 1–20