Patrick D. Hsu
Title
Cited by
Cited by
Year
Multiplex genome engineering using CRISPR/Cas systems
L Cong, FA Ran, D Cox, S Lin, R Barretto, N Habib, PD Hsu, X Wu, ...
Science 339 (6121), 819-823, 2013
124582013
Genome engineering using the CRISPR-Cas9 system
FA Ran, PD Hsu, J Wright, V Agarwala, DA Scott, F Zhang
Nature protocols 8 (11), 2281-2308, 2013
74562013
Development and applications of CRISPR-Cas9 for genome engineering
PD Hsu, ES Lander, F Zhang
Cell 157 (6), 1262-1278, 2014
46592014
DNA targeting specificity of RNA-guided Cas9 nucleases
PD Hsu, DA Scott, JA Weinstein, FA Ran, S Konermann, V Agarwala, Y Li, ...
Nature biotechnology 31 (9), 827-832, 2013
38712013
Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity
FA Ran, PD Hsu, CY Lin, JS Gootenberg, S Konermann, AE Trevino, ...
Cell 154 (6), 1380-1389, 2013
31612013
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
S Konermann, MD Brigham, AE Trevino, J Joung, OO Abudayyeh, ...
Nature 517 (7536), 583-588, 2015
18492015
Crystal structure of Cas9 in complex with guide RNA and target DNA
H Nishimasu, FA Ran, PD Hsu, S Konermann, SI Shehata, N Dohmae, ...
Cell 156 (5), 935-949, 2014
15432014
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells
X Wu, DA Scott, AJ Kriz, AC Chiu, PD Hsu, DB Dadon, AW Cheng, ...
Nature biotechnology 32 (7), 670-676, 2014
8452014
Optical control of mammalian endogenous transcription and epigenetic states
S Konermann, MD Brigham, AE Trevino, PD Hsu, M Heidenreich, L Cong, ...
Nature 500 (7463), 472-476, 2013
8372013
Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus
W Yang, N Shen, DQ Ye, Q Liu, Y Zhang, XX Qian, N Hirankarn, D Ying, ...
PLoS genetics 6 (2), e1000841, 2010
4062010
Transcriptome engineering with RNA-targeting type VI-D CRISPR effectors
S Konermann, P Lotfy, NJ Brideau, J Oki, MN Shokhirev, PD Hsu
Cell 173 (3), 665-676. e14, 2018
3872018
CRISPR-Cas component systems, methods and compositions for sequence manipulation
F Zhang
US Patent 8,795,965, 2014
2902014
Structure and engineering of Francisella novicida Cas9
H Hirano, JS Gootenberg, T Horii, OO Abudayyeh, M Kimura, PD Hsu, ...
Cell 164 (5), 950-961, 2016
2442016
Methods for optimizing CRISPR-Cas9 genome editing specificity
J Tycko, VE Myer, PD Hsu
Molecular cell 63 (3), 355-370, 2016
2382016
Engineering of systems, methods and optimized guide compositions for sequence manipulation
F Zhang, L Cong, P Hsu, RAN Fei
US Patent 8,906,616, 2014
2262014
Delivery and specificity of CRISPR/Cas9 genome editing technologies for human gene therapy
JL Gori, PD Hsu, ML Maeder, S Shen, GG Welstead, D Bumcrot
Human gene therapy 26 (7), 443-451, 2015
1862015
Engineering of systems, methods and optimized guide compositions for sequence manipulation
F Zhang, L Cong, P Hsu, RAN Fei
US Patent App. 14/104,990, 2014
1692014
Multiplex genome engineering using CRISPR/Cas systems
F Le Cong, D Cox, S Lin, R Barretto, N Habib, PD Hsu, X Wu, W Jiang, ...
Science (New York, NY) 339 (6121), 819, 2013
1682013
Crispr-cas component systems, methods and compositions for sequence manipulation
F Zhang, L Cong, DBT Cox, P Hsu, LIN Shuailiang, RAN Fei, RJ Platt, ...
US Patent App. 14/105,035, 2014
1432014
Engineering of systems, methods and optimized guide compositions for sequence manipulation
F Zhang, L Cong, P Hsu, RAN Fei
US Patent App. 14/704,551, 2015
1252015
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