| Clearance of p16 Ink4a-positive senescent cells delays ageing-associated disorders DJ Baker, T Wijshake, T Tchkonia, NK LeBrasseur, BG Childs, ... Nature 479 (7372), 232-236, 2011 | 2200 | 2011 |
| AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis T Okuda, J Van Deursen, SW Hiebert, G Grosveld, JR Downing Cell 84 (2), 321-330, 1996 | 2047 | 1996 |
| Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4 HU Wang, ZF Chen, DJ Anderson Cell 93 (5), 741-753, 1998 | 1857 | 1998 |
| Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene K Shimoda, J van Deursent, MY Sangster, SR Sarawar, RT Carson, ... Nature 380 (6575), 630-633, 1996 | 1446 | 1996 |
| Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses S Teglund, C McKay, E Schuetz, JM Van Deursen, D Stravopodis, ... Cell 93 (5), 841-850, 1998 | 1388 | 1998 |
| Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells WE Thierfelder, JM van Deursen, K Yamamoto, RA Tripp, SR Sarawar, ... Nature 382 (6587), 171-174, 1996 | 1278 | 1996 |
| Naturally occurring p16Ink4a-positive cells shorten healthy lifespan DJ Baker, BG Childs, M Durik, ME Wijers, CJ Sieben, J Zhong, ... Nature 530 (7589), 184-189, 2016 | 1264 | 2016 |
| The role of senescent cells in ageing JM Van Deursen Nature 509 (7501), 439-446, 2014 | 1252 | 2014 |
| Jak2 is essential for signaling through a variety of cytokine receptors E Parganas, D Wang, D Stravopodis, DJ Topham, JC Marine, S Teglund, ... Cell 93 (3), 385-395, 1998 | 1221 | 1998 |
| Cellular senescence and the senescent secretory phenotype: therapeutic opportunities T Tchkonia, Y Zhu, J Van Deursen, J Campisi, JL Kirkland The Journal of clinical investigation 123 (3), 966-972, 2013 | 1033 | 2013 |
| Cellular senescence in aging and age-related disease: from mechanisms to therapy BG Childs, M Durik, DJ Baker, JM Van Deursen Nature medicine 21 (12), 1424-1435, 2015 | 870 | 2015 |
| Fat tissue, aging, and cellular senescence T Tchkonia, DE Morbeck, T Von Zglinicki, J Van Deursen, J Lustgarten, ... Aging cell 9 (5), 667-684, 2010 | 731 | 2010 |
| BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice DJ Baker, KB Jeganathan, JD Cameron, M Thompson, S Juneja, ... Nature genetics 36 (7), 744-749, 2004 | 716 | 2004 |
| MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals Z Lou, K Minter-Dykhouse, S Franco, M Gostissa, MA Rivera, A Celeste, ... Molecular cell 21 (2), 187-200, 2006 | 700 | 2006 |
| Defective lymphoid development in mice lacking Jak3 T Nosaka, JMA Van Deursen, RA Tripp, WE Thierfelder, BA Witthuhn, ... Science 270 (5237), 800-802, 1995 | 699 | 1995 |
| Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells R Moriggl, DJ Topham, S Teglund, V Sexl, C McKay, D Wang, ... Immunity 10 (2), 249-259, 1999 | 631 | 1999 |
| Regulation of the T-independent humoral response by TACI GU von Bülow, JM van Deursen, RJ Bram Immunity 14 (5), 573-582, 2001 | 557 | 2001 |
| Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation H Huang, KM Regan, F Wang, D Wang, DI Smith, JMA Van Deursen, ... Proceedings of the National Academy of Sciences 102 (5), 1649-1654, 2005 | 549 | 2005 |
| The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88 M Fornerod, J Van Deursen, S Van Baal, A Reynolds, D Davis, KG Murti, ... The EMBO journal 16 (4), 807-816, 1997 | 524 | 1997 |
| Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment OH Jeon, C Kim, RM Laberge, M Demaria, S Rathod, AP Vasserot, ... Nature medicine 23 (6), 775, 2017 | 499 | 2017 |
