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James P. R. Connolly
James P. R. Connolly
Verified email at newcastle.ac.uk
Title
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Cited by
Year
Antibiotics induce sustained dysregulation of intestinal T cell immunity by perturbing macrophage homeostasis
NA Scott, A Andrusaite, P Andersen, M Lawson, C Alcon-Giner, C Leclaire, ...
Science translational medicine 10 (464), eaao4755, 2018
2322018
From ingestion to colonization: the influence of the host environment on regulation of the LEE encoded type III secretion system in enterohaemorrhagic Escherichia coli
JPR Connolly, BB Finlay, AJ Roe
Frontiers in Microbiology 6, 146339, 2015
702015
The host metabolite D-serine contributes to bacterial niche specificity through gene selection
JPR Connolly, RJ Goldstone, K Burgess, RJ Cogdell, SA Beatson, ...
The ISME journal 9 (4), 1039-1051, 2015
662015
A highly conserved bacterial D-serine uptake system links host metabolism and virulence
JPR Connolly, M Gabrielsen, RJ Goldstone, R Grinter, D Wang, ...
PLoS pathogens 12 (1), e1005359, 2016
642016
Propionic acid promotes the virulent phenotype of Crohn’s disease-associated adherent-invasive Escherichia coli
MJ Ormsby, SA Johnson, N Carpena, LM Meikle, RJ Goldstone, ...
Cell reports 30 (7), 2297-2305. e5, 2020
582020
Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion
JPR Connolly, SL Slater, N O’Boyle, RJ Goldstone, VF Crepin, ...
Nature Communications 9 (1), 4187, 2018
562018
Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion
JPR Connolly, SL Slater, N O’Boyle, RJ Goldstone, VF Crepin, ...
Nature Communications 9 (1), 4187, 2018
562018
The metabolic enzyme AdhE controls the virulence of Escherichia coli O157:H7
KSH Beckham, JPR Connolly, JM Ritchie, D Wang, JA Gawthorne, ...
Molecular microbiology 93 (1), 199-211, 2014
542014
Postgenomics Characterization of an Essential Genetic Determinant of Mammary Pathogenic Escherichia coli
SE Blum, RJ Goldstone, JPR Connolly, M Répérant-Ferter, P Germon, ...
MBio 9 (2), 10.1128/mbio. 00423-18, 2018
362018
Characterization of the mode of action of aurodox, a type III secretion system inhibitor from Streptomyces goldiniensis
RE McHugh, N O’Boyle, JPR Connolly, PA Hoskisson, AJ Roe
Infection and immunity 87 (2), 10.1128/iai. 00595-18, 2019
282019
Control freaks—signals and cues governing the regulation of virulence in attaching and effacing pathogens
NCA Turner, JPR Connolly, AJ Roe
Biochemical Society Transactions 47 (1), 229-238, 2019
262019
The highly conserved Escherichia coli transcription factor yhaJ regulates aromatic compound degradation
N Palevsky, B Shemer, JPR Connolly, S Belkin
Frontiers in Microbiology 7, 213499, 2016
232016
Genomic and transcriptomic characterization of Pseudomonas aeruginosa small colony variants derived from a chronic infection model
S Irvine, B Bunk, HK Bayes, C Spröer, JPR Connolly, A Six, TJ Evans, ...
Microbial genomics 5 (4), e000262, 2019
222019
Novel compounds targeting the enterohemorrhagic Escherichia coli type three secretion system reveal insights into mechanisms of secretion inhibition
R Zambelloni, JPR Connolly, A Huerta Uribe, K Burgess, R Marquez, ...
Molecular Microbiology 105 (4), 606-619, 2017
222017
Distinct intraspecies virulence mechanisms regulated by a conserved transcription factor
JPR Connolly, N O’Boyle, NCA Turner, DF Browning, AJ Roe
Proceedings of the National Academy of Sciences 116 (39), 19695-19704, 2019
202019
Identification and Characterization of Novel Compounds Blocking Shiga Toxin Expression in Escherichia coli O157:H7
A Huerta-Uribe, ZR Marjenberg, N Yamaguchi, S Fitzgerald, ...
Frontiers in microbiology 7, 1930, 2016
142016
Intracellular d-Serine Accumulation Promotes Genetic Diversity via Modulated Induction of RecA in Enterohemorrhagic Escherichia coli
JPR Connolly, AJ Roe
Journal of Bacteriology 198 (24), 3318-3328, 2016
112016
Tracking elusive cargo: Illuminating spatio‐temporal Type 3 effector protein dynamics using reporters
N O'Boyle, JPR Connolly, AJ Roe
Cellular microbiology 20 (1), e12797, 2018
102018
When and where? Pathogenic Escherichia coli differentially sense host D-serine using a universal transporter system to monitor their environment
JPR Connolly, AJ Roe
Microbial cell 3 (4), 181, 2016
82016
Genomic inversion drives small colony variant formation and increased virulence in P. aeruginosa
S Irvine, B Bunk, HK Bayes, C Sprӧer, JPR Connolly, A Six, TJ Evans, ...
bioRxiv, 356386, 2018
12018
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Articles 1–20