| The TSC1-2 tumor suppressor controls insulin–PI3K signaling via regulation of IRS proteins LS Harrington, GM Findlay, A Gray, T Tolkacheva, S Wigfield, H Rebholz, ... The Journal of cell biology 166 (2), 213-223, 2004 | 1382 | 2004 |
| Redox regulation of PI 3-kinase signalling via inactivation of PTEN NR Leslie, D Bennett, YE Lindsay, H Stewart, A Gray, CP Downes The EMBO journal 22 (20), 5501-5510, 2003 | 705 | 2003 |
| Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR) JM García-Martínez, J Moran, RG Clarke, A Gray, SC Cosulich, ... Biochemical Journal 421 (1), 29-42, 2009 | 573 | 2009 |
| A crucial role for the p110δ subunit of phosphatidylinositol 3-kinase in B cell development and activation E Clayton, G Bardi, SE Bell, D Chantry, CP Downes, A Gray, ... The Journal of experimental medicine 196 (6), 753-763, 2002 | 571 | 2002 |
| Fructose-1, 6-bisphosphate and aldolase mediate glucose sensing by AMPK CS Zhang, SA Hawley, Y Zong, M Li, Z Wang, A Gray, T Ma, J Cui, ... Nature 548 (7665), 112-116, 2017 | 548 | 2017 |
| Role of phosphatidylinositol 3, 4, 5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1 RA Currie, KS Walker, A Gray, M Deak, A Casamayor, CP Downes, ... Biochemical Journal 337 (3), 575-583, 1999 | 515 | 1999 |
| Essential role for the p110δ phosphoinositide 3-kinase in the allergic response K Ali, A Bilancio, M Thomas, W Pearce, AM Gilfillan, C Tkaczyk, N Kuehn, ... Nature 431 (7011), 1007-1011, 2004 | 506 | 2004 |
| Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking LV Sinclair, D Finlay, C Feijoo, GH Cornish, A Gray, A Ager, K Okkenhaug, ... Nature immunology 9 (5), 513-521, 2008 | 443 | 2008 |
| Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking LV Sinclair, D Finlay, C Feijoo, GH Cornish, A Gray, A Ager, K Okkenhaug, ... Nature immunology 9 (5), 513-521, 2008 | 443 | 2008 |
| Intracellular ceramide synthesis and protein kinase Cζ activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells DJ Powell, S Turban, A Gray, E Hajduch, HS Hundal Biochemical Journal 382 (2), 619-629, 2004 | 327 | 2004 |
| Probing phosphoinositide functions in signaling and membrane trafficking CP Downes, A Gray, JM Lucocq Trends in cell biology 15 (5), 259-268, 2005 | 286 | 2005 |
| The pleckstrin homology domains of protein kinase B and GRP1 (general receptor for phosphoinositides-1) are sensitive and selective probes for the cellular detection of … A Gray, J V AN DER KAAY, CP Downes Biochemical Journal 344 (3), 929-936, 1999 | 238 | 1999 |
| Regulation of the Rac1-specific exchange factor Tiam1 involves both phosphoinositide 3-kinase-dependent and-independent components IN FLEMING, A GRAY, CP DOWNES Biochemical Journal 351 (1), 173-182, 2000 | 193 | 2000 |
| Activity of any class IA PI3K isoform can sustain cell proliferation and survival LC Foukas, IM Berenjeno, A Gray, A Khwaja, B Vanhaesebroeck Proceedings of the National Academy of Sciences 107 (25), 11381-11386, 2010 | 192 | 2010 |
| Leptin and insulin stimulation of signalling pathways in arcuate nucleus neurones: PI3K dependent actin reorganization and KATPchannel activation S Mirshamsi, HA Laidlaw, K Ning, E Anderson, LA Burgess, A Gray, ... BMC neuroscience 5, 1-18, 2004 | 189 | 2004 |
| PTEN regulates PI (3, 4) P2 signaling downstream of class I PI3K M Malek, A Kielkowska, T Chessa, KE Anderson, D Barneda, P Pir, ... Molecular cell 68 (3), 566-580. e10, 2017 | 182 | 2017 |
| Localization of agonist-sensitive PtdIns(3,4,5)P3 reveals a nuclear pool that is insensitive to PTEN expression Y Lindsay, D McCoull, L Davidson, NR Leslie, A Fairservice, A Gray, ... Journal of cell science 119 (24), 5160-5168, 2006 | 181 | 2006 |
| Nonradioactive methods for the assay of phosphoinositide 3-kinases and phosphoinositide phosphatases and selective detection of signaling lipids in cell and tissue extracts A Gray, H Olsson, IH Batty, L Priganica, CP Downes Analytical biochemistry 313 (2), 234-245, 2003 | 173 | 2003 |
| Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd (3, 4) P2 and the multi-PDZ-domain-containing protein MUPP1 in vivo WA Kimber, L Trinkle-Mulcahy, PCF Cheung, M Deak, LJ Marsden, ... Biochemical Journal 361 (3), 525-536, 2002 | 164 | 2002 |
| Suppression of cellular proliferation and invasion by the concerted lipid and protein phosphatase activities of PTEN L Davidson, H Maccario, NM Perera, X Yang, L Spinelli, P Tibarewal, ... Oncogene 29 (5), 687-697, 2010 | 142 | 2010 |
