TXNIP regulates peripheral glucose metabolism in humans H Parikh, E Carlsson, WA Chutkow, LE Johansson, H Storgaard, ... PLoS medicine 4 (5), e158, 2007 | 559 | 2007 |
Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure S Shah, A Henry, C Roselli, H Lin, G Sveinbjörnsson, G Fatemifar, ... Nature communications 11 (1), 163, 2020 | 525 | 2020 |
The interaction of thioredoxin with Txnip: evidence for formation of a mixed disulfide by disulfide exchange P Patwari, LJ Higgins, WA Chutkow, J Yoshioka, RT Lee Journal of Biological Chemistry 281 (31), 21884-21891, 2006 | 376 | 2006 |
Cloning, tissue expression, and chromosomal localization of SUR2, the putative drug-binding subunit of cardiac, skeletal muscle, and vascular KATP channels WA Chutkow, MC Simon, MM Le Beau, CF Burant Diabetes 45 (10), 1439-1445, 1996 | 328 | 1996 |
Episodic coronary artery vasospasm and hypertension develop in the absence of Sur2 KATP channels WA Chutkow, J Pu, MT Wheeler, T Wada, JC Makielski, CF Burant, ... The Journal of clinical investigation 110 (2), 203-208, 2002 | 308 | 2002 |
Thioredoxin-interacting protein (Txnip) is a critical regulator of hepatic glucose production WA Chutkow, P Patwari, J Yoshioka, RT Lee Journal of Biological Chemistry 283 (4), 2397-2406, 2008 | 237 | 2008 |
Thioredoxin-independent regulation of metabolism by the α-arrestin proteins P Patwari, WA Chutkow, K Cummings, VLRM Verstraeten, J Lammerding, ... Journal of Biological Chemistry 284 (37), 24996-25003, 2009 | 223 | 2009 |
Deletion of the α-arrestin protein Txnip in mice promotes adiposity and adipogenesis while preserving insulin sensitivity WA Chutkow, AL Birkenfeld, JD Brown, HY Lee, DW Frederick, ... Diabetes 59 (6), 1424-1434, 2010 | 183 | 2010 |
Deletion of thioredoxin-interacting protein in mice impairs mitochondrial function but protects the myocardium from ischemia-reperfusion injury J Yoshioka, WA Chutkow, S Lee, JB Kim, J Yan, R Tian, ML Lindsey, ... The Journal of clinical investigation 122 (1), 267-279, 2012 | 182 | 2012 |
Disruption of Sur2-containing KATP channels enhances insulin-stimulated glucose uptake in skeletal muscle WA Chutkow, V Samuel, PA Hansen, J Pu, CR Valdivia, JC Makielski, ... Proceedings of the National Academy of Sciences 98 (20), 11760-11764, 2001 | 150 | 2001 |
The arrestin domain-containing 3 protein regulates body mass and energy expenditure P Patwari, V Emilsson, EE Schadt, WA Chutkow, S Lee, A Marsili, ... Cell metabolism 14 (5), 671-683, 2011 | 133 | 2011 |
Alternative splicing of sur2 Exon 17 regulates nucleotide sensitivity of the ATP-sensitive potassium channel WA Chutkow, JC Makielski, DJ Nelson, CF Burant, Z Fan Journal of Biological Chemistry 274 (19), 13656-13665, 1999 | 124 | 1999 |
Targeted deletion of thioredoxin-interacting protein regulates cardiac dysfunction in response to pressure overload J Yoshioka, K Imahashi, SA Gabel, WA Chutkow, AA Burds, J Gannon, ... Circulation research 101 (12), 1328-1338, 2007 | 119 | 2007 |
Myocardial infarction triggers chronic cardiac autoimmunity in type 1 diabetes RV Gottumukkala, HJ Lv, L Cornivelli, AJ Wagers, RY Kwong, R Bronson, ... Science translational medicine 4 (138), 138ra80-138ra80, 2012 | 76 | 2012 |
The effects of licogliflozin, a dual SGLT1/2 inhibitor, on body weight in obese patients with or without diabetes YL He, W Haynes, CD Meyers, A Amer, Y Zhang, P Mahling, ... Diabetes, obesity and metabolism 21 (6), 1311-1321, 2019 | 72 | 2019 |
Thioredoxin Regulates Adipogenesis through Thioredoxin-interacting Protein (Txnip) Protein Stability*♦ WA Chutkow, RT Lee Journal of Biological Chemistry 286 (33), 29139-29145, 2011 | 67 | 2011 |
Thioredoxin‐interacting protein regulates protein disulfide isomerases and endoplasmic reticulum stress S Lee, S Min Kim, J Dotimas, L Li, EP Feener, S Baldus, RB Myers, ... EMBO molecular medicine 6 (6), 732-743, 2014 | 54 | 2014 |
A crisis in late pregnancy AS Desai, WA Chutkow, E Edelman, KE Economy, GW Dec Jr New England Journal of Medicine 361 (23), 2271-2277, 2009 | 42 | 2009 |
Evidence of K-ATP channels in native cardiac cells without SUR. JL Pu, T Wada, C Valdivia, WA Chutkow, CF Burant, JC Makielski Biophysical Journal 80 (1), 625A-626A, 2001 | 17 | 2001 |
Aptamer proteomics for biomarker discovery in heart failure with reduced ejection fraction L Zhang, JW Cunningham, BL Claggett, J Jacob, MM Mendelson, ... Circulation 146 (18), 1411-1414, 2022 | 12 | 2022 |