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Richard Orton
Richard Orton
CVR Bioinformatics, MRC-University of Glasgow Centre for Virus Research
Verified email at glasgow.ac.uk - Homepage
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Cited by
Year
Evaluating the effects of SARS-CoV-2 spike mutation D614G on transmissibility and pathogenicity
E Volz, V Hill, JT McCrone, A Price, D Jorgensen, O’Toole, J Southgate, ...
Cell 184 (1), 64-75. e11, 2021
7922021
Virus taxonomy: the database of the International Committee on Taxonomy of Viruses (ICTV)
EJ Lefkowitz, DM Dempsey, RC Hendrickson, RJ Orton, SG Siddell, ...
Nucleic acids research 46 (D1), D708-D717, 2018
6312018
Virus taxonomy in the age of metagenomics
P Simmonds, MJ Adams, M Benkő, M Breitbart, JR Brister, EB Carstens, ...
Nature Reviews Microbiology 15 (3), 161-168, 2017
5132017
Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathway
RJ Orton, OE Sturm, V Vyshemirsky, M Calder, DR Gilbert, W Kolch
Biochemical Journal 392 (2), 249-261, 2005
4932005
Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B. 1.617. 2) compared with alpha (B. 1.1. 7) variants of concern: a cohort study
KA Twohig, T Nyberg, A Zaidi, S Thelwall, MA Sinnathamby, S Aliabadi, ...
The Lancet Infectious Diseases 22 (1), 35-42, 2022
3642022
Late Ebola virus relapse causing meningoencephalitis: a case report
M Jacobs, A Rodger, DJ Bell, S Bhagani, I Cropley, A Filipe, RJ Gifford, ...
The Lancet 388 (10043), 498-503, 2016
3322016
Cell fate decisions are specified by the dynamic ERK interactome
A Von Kriegsheim, D Baiocchi, M Birtwistle, D Sumpton, W Bienvenut, ...
Nature cell biology 11 (12), 1458-1464, 2009
3052009
The mammalian MAPK/ERK pathway exhibits properties of a negative feedback amplifier
OE Sturm, R Orton, J Grindlay, M Birtwistle, V Vyshemirsky, D Gilbert, ...
Science signaling 3 (153), ra90-ra90, 2010
2752010
Changes in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B. 1.1. 7: an ecological study
MS Graham, CH Sudre, A May, M Antonelli, B Murray, T Varsavsky, ...
The Lancet Public Health 6 (5), e335-e345, 2021
2382021
Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B. 1.1. 7
B Meng, SA Kemp, G Papa, R Datir, IATM Ferreira, S Marelli, WT Harvey, ...
Cell reports 35 (13), 109292, 2021
2302021
Fundamental properties of the mammalian innate immune system revealed by multispecies comparison of type I interferon responses
AE Shaw, J Hughes, Q Gu, A Behdenna, JB Singer, T Dennis, RJ Orton, ...
PLoS biology 15 (12), e2004086, 2017
1862017
Whole Genome Sequencing Reveals Local Transmission Patterns of Mycobacterium bovis in Sympatric Cattle and Badger Populations
R Biek, A O'Hare, D Wright, T Mallon, C McCormick, RJ Orton, ...
PLoS pathogens 8 (11), e1003008, 2012
1812012
Changes to virus taxonomy and the Statutes ratified by the International Committee on Taxonomy of Viruses (2020)
PJ Walker, SG Siddell, EJ Lefkowitz, AR Mushegian, EM Adriaenssens, ...
Archives of virology 165 (11), 2737-2748, 2020
1712020
Computational methodologies for modelling, analysis and simulation of signalling networks
D Gilbert, H Fuss, X Gu, R Orton, S Robinson, V Vyshemirsky, MJ Kurth, ...
Briefings in Bioinformatics 7 (4), 339-353, 2006
1182006
Predicting reservoir hosts and arthropod vectors from evolutionary signatures in RNA virus genomes
SA Babayan, RJ Orton, DG Streicker
Science 362 (6414), 577-580, 2018
1082018
A structured approach for the engineering of biochemical network models, illustrated for signalling pathways
R Breitling, D Gilbert, M Heiner, R Orton
Briefings in bioinformatics 9 (5), 404-421, 2008
1032008
Analysis of signalling pathways using continuous time Markov chains
M Calder, V Vyshemirsky, D Gilbert, R Orton
Transactions on Computational Systems Biology VI, 44-67, 2006
1022006
Changes to virus taxonomy and to the International Code of Virus Classification and Nomenclature ratified by the International Committee on Taxonomy of Viruses (2021)
PJ Walker, SG Siddell, EJ Lefkowitz, AR Mushegian, EM Adriaenssens, ...
Archives of Virology 166 (9), 2633-2648, 2021
982021
The hyper-transmissible SARS-CoV-2 Omicron variant exhibits significant antigenic change, vaccine escape and a switch in cell entry mechanism
BJ Willett, J Grove, O MacLean, C Wilkie, N Logan, G De Lorenzo, ...
MedRxiv, 2022
912022
A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research
SJ Rihn, A Merits, S Bakshi, ML Turnbull, A Wickenhagen, AJT Alexander, ...
PLoS biology 19 (2), e3001091, 2021
912021
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