| Evaluating the effects of SARS-CoV-2 spike mutation D614G on transmissibility and pathogenicity E Volz, V Hill, JT McCrone, A Price, D Jorgensen, Á O’Toole, J Southgate, ... Cell 184 (1), 64-75. e11, 2021 | 792 | 2021 |
| Virus taxonomy: the database of the International Committee on Taxonomy of Viruses (ICTV) EJ Lefkowitz, DM Dempsey, RC Hendrickson, RJ Orton, SG Siddell, ... Nucleic acids research 46 (D1), D708-D717, 2018 | 631 | 2018 |
| Virus taxonomy in the age of metagenomics P Simmonds, MJ Adams, M Benkő, M Breitbart, JR Brister, EB Carstens, ... Nature Reviews Microbiology 15 (3), 161-168, 2017 | 513 | 2017 |
| Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathway RJ Orton, OE Sturm, V Vyshemirsky, M Calder, DR Gilbert, W Kolch Biochemical Journal 392 (2), 249-261, 2005 | 493 | 2005 |
| Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B. 1.617. 2) compared with alpha (B. 1.1. 7) variants of concern: a cohort study KA Twohig, T Nyberg, A Zaidi, S Thelwall, MA Sinnathamby, S Aliabadi, ... The Lancet Infectious Diseases 22 (1), 35-42, 2022 | 364 | 2022 |
| Late Ebola virus relapse causing meningoencephalitis: a case report M Jacobs, A Rodger, DJ Bell, S Bhagani, I Cropley, A Filipe, RJ Gifford, ... The Lancet 388 (10043), 498-503, 2016 | 332 | 2016 |
| Cell fate decisions are specified by the dynamic ERK interactome A Von Kriegsheim, D Baiocchi, M Birtwistle, D Sumpton, W Bienvenut, ... Nature cell biology 11 (12), 1458-1464, 2009 | 305 | 2009 |
| The mammalian MAPK/ERK pathway exhibits properties of a negative feedback amplifier OE Sturm, R Orton, J Grindlay, M Birtwistle, V Vyshemirsky, D Gilbert, ... Science signaling 3 (153), ra90-ra90, 2010 | 275 | 2010 |
| Changes in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B. 1.1. 7: an ecological study MS Graham, CH Sudre, A May, M Antonelli, B Murray, T Varsavsky, ... The Lancet Public Health 6 (5), e335-e345, 2021 | 238 | 2021 |
| Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B. 1.1. 7 B Meng, SA Kemp, G Papa, R Datir, IATM Ferreira, S Marelli, WT Harvey, ... Cell reports 35 (13), 109292, 2021 | 230 | 2021 |
| Fundamental properties of the mammalian innate immune system revealed by multispecies comparison of type I interferon responses AE Shaw, J Hughes, Q Gu, A Behdenna, JB Singer, T Dennis, RJ Orton, ... PLoS biology 15 (12), e2004086, 2017 | 186 | 2017 |
| Whole Genome Sequencing Reveals Local Transmission Patterns of Mycobacterium bovis in Sympatric Cattle and Badger Populations R Biek, A O'Hare, D Wright, T Mallon, C McCormick, RJ Orton, ... PLoS pathogens 8 (11), e1003008, 2012 | 181 | 2012 |
| Changes to virus taxonomy and the Statutes ratified by the International Committee on Taxonomy of Viruses (2020) PJ Walker, SG Siddell, EJ Lefkowitz, AR Mushegian, EM Adriaenssens, ... Archives of virology 165 (11), 2737-2748, 2020 | 171 | 2020 |
| Computational methodologies for modelling, analysis and simulation of signalling networks D Gilbert, H Fuss, X Gu, R Orton, S Robinson, V Vyshemirsky, MJ Kurth, ... Briefings in Bioinformatics 7 (4), 339-353, 2006 | 118 | 2006 |
| Predicting reservoir hosts and arthropod vectors from evolutionary signatures in RNA virus genomes SA Babayan, RJ Orton, DG Streicker Science 362 (6414), 577-580, 2018 | 108 | 2018 |
| A structured approach for the engineering of biochemical network models, illustrated for signalling pathways R Breitling, D Gilbert, M Heiner, R Orton Briefings in bioinformatics 9 (5), 404-421, 2008 | 103 | 2008 |
| Analysis of signalling pathways using continuous time Markov chains M Calder, V Vyshemirsky, D Gilbert, R Orton Transactions on Computational Systems Biology VI, 44-67, 2006 | 102 | 2006 |
| Changes to virus taxonomy and to the International Code of Virus Classification and Nomenclature ratified by the International Committee on Taxonomy of Viruses (2021) PJ Walker, SG Siddell, EJ Lefkowitz, AR Mushegian, EM Adriaenssens, ... Archives of Virology 166 (9), 2633-2648, 2021 | 98 | 2021 |
| The hyper-transmissible SARS-CoV-2 Omicron variant exhibits significant antigenic change, vaccine escape and a switch in cell entry mechanism BJ Willett, J Grove, O MacLean, C Wilkie, N Logan, G De Lorenzo, ... MedRxiv, 2022 | 91 | 2022 |
| A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research SJ Rihn, A Merits, S Bakshi, ML Turnbull, A Wickenhagen, AJT Alexander, ... PLoS biology 19 (2), e3001091, 2021 | 91 | 2021 |
David GilbertProfessor of Computer Science, Brunel UniversityVerified email at brunel.ac.uk
