Richard Orton
Richard Orton
CVR Bioinformatics, MRC-University of Glasgow Centre for Virus Research
Verified email at glasgow.ac.uk - Homepage
Title
Cited by
Cited by
Year
Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathway
RJ Orton, OE Sturm, V Vyshemirsky, M Calder, DR Gilbert, W Kolch
Biochemical Journal 392 (2), 249-261, 2005
4312005
Consensus statement: virus taxonomy in the age of metagenomics
P Simmonds, MJ Adams, M Benkő, M Breitbart, JR Brister, EB Carstens, ...
Nature Reviews Microbiology 15 (3), 161-168, 2017
3332017
Cell fate decisions are specified by the dynamic ERK interactome
A Von Kriegsheim, D Baiocchi, M Birtwistle, D Sumpton, W Bienvenut, ...
Nature cell biology 11 (12), 1458-1464, 2009
2712009
Virus taxonomy: the database of the International Committee on Taxonomy of Viruses (ICTV)
EJ Lefkowitz, DM Dempsey, RC Hendrickson, RJ Orton, SG Siddell, ...
Nucleic acids research 46 (D1), D708-D717, 2018
2542018
Late Ebola virus relapse causing meningoencephalitis: a case report
M Jacobs, A Rodger, DJ Bell, S Bhagani, I Cropley, A Filipe, RJ Gifford, ...
The Lancet 388 (10043), 498-503, 2016
2352016
The mammalian MAPK/ERK pathway exhibits properties of a negative feedback amplifier
OE Sturm, R Orton, J Grindlay, M Birtwistle, V Vyshemirsky, D Gilbert, ...
Science signaling 3 (153), ra90-ra90, 2010
2332010
Whole genome sequencing reveals local transmission patterns of Mycobacterium bovis in sympatric cattle and badger populations
R Biek, A O'Hare, D Wright, T Mallon, C McCormick, RJ Orton, ...
PLoS Pathog 8 (11), e1003008, 2012
1402012
Computational methodologies for modelling, analysis and simulation of signalling networks
D Gilbert, H Fuss, X Gu, R Orton, S Robinson, V Vyshemirsky, MJ Kurth, ...
Briefings in Bioinformatics 7 (4), 339-353, 2006
1132006
Analysis of signalling pathways using continuous time Markov chains
M Calder, V Vyshemirsky, D Gilbert, R Orton
Transactions on Computational Systems Biology VI, 44-67, 2006
1002006
A structured approach for the engineering of biochemical network models, illustrated for signalling pathways
R Breitling, D Gilbert, M Heiner, R Orton
Briefings in bioinformatics 9 (5), 404-421, 2008
942008
Fundamental properties of the mammalian innate immune system revealed by multispecies comparison of type I interferon responses
AE Shaw, J Hughes, Q Gu, A Behdenna, JB Singer, T Dennis, RJ Orton, ...
PLoS biology 15 (12), e2004086, 2017
882017
Analysis of signalling pathways using the PRISM model checker
M Calder, V Vyshemirsky, D Gilbert, R Orton
University of Edinburgh, 2005
762005
Computational modelling of cancerous mutations in the EGFR/ERK signalling pathway
RJ Orton, ME Adriaens, A Gormand, OE Sturm, W Kolch, DR Gilbert
BMC systems biology 3 (1), 1-17, 2009
672009
Risk factors for bovine tuberculosis at the national level in Great Britain
PR Bessell, R Orton, PCL White, MR Hutchings, RR Kao
BMC Veterinary Research 8 (1), 51, 2012
512012
50 years of the International Committee on Taxonomy of Viruses: progress and prospects
MJ Adams, EJ Lefkowitz, AMQ King, B Harrach, RL Harrison, NJ Knowles, ...
Archives of virology 162 (5), 1441-1446, 2017
432017
Estimating epidemiological parameters for bovine tuberculosis in British cattle using a Bayesian partial-likelihood approach
A O'Hare, RJ Orton, PR Bessell, RR Kao
Proceedings of the Royal Society B: Biological Sciences 281 (1783), 20140248, 2014
432014
Predicting reservoir hosts and arthropod vectors from evolutionary signatures in RNA virus genomes
SA Babayan, RJ Orton, DG Streicker
Science 362 (6414), 577-580, 2018
412018
Use of bacterial whole-genome sequencing to investigate local persistence and spread in bovine tuberculosis
H Trewby, D Wright, EL Breadon, SJ Lycett, TR Mallon, C McCormick, ...
Epidemics 14, 26-35, 2016
392016
Distinguishing low frequency mutations from RT-PCR and sequence errors in viral deep sequencing data
RJ Orton, CF Wright, MJ Morelli, DJ King, DJ Paton, DP King, DT Haydon
BMC genomics 16 (1), 229, 2015
372015
Next-generation sequencing in veterinary medicine: how can the massive amount of information arising from high-throughput technologies improve diagnosis, control, and†…
S Van Borm, S BelŠk, G Freimanis, A Fusaro, F Granberg, D HŲper, ...
Veterinary infection biology: molecular diagnostics and high-throughput†…, 2015
342015
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