HITS-CLIP yields genome-wide insights into brain alternative RNA processing DD Licatalosi, A Mele, JJ Fak, J Ule, M Kayikci, SW Chi, TA Clark, ... Nature 456 (7221), 464-469, 2008 | 1592 | 2008 |
CLIP identifies Nova-regulated RNA networks in the brain J Ule, KB Jensen, M Ruggiu, A Mele, A Ule, RB Darnell Science 302 (5648), 1212-1215, 2003 | 1358 | 2003 |
Characterizing the RNA targets and position-dependent splicing regulation by TDP-43 JR Tollervey, T Curk, B Rogelj, M Briese, M Cereda, M Kayikci, J König, ... Nature neuroscience 14 (4), 452-458, 2011 | 1272 | 2011 |
iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution J König, K Zarnack, G Rot, T Curk, M Kayikci, B Zupan, DJ Turner, ... Nature structural & molecular biology 17 (7), 909-915, 2010 | 1268 | 2010 |
CLIP: a method for identifying protein–RNA interaction sites in living cells J Ule, K Jensen, A Mele, RB Darnell Methods 37 (4), 376-386, 2005 | 744 | 2005 |
An RNA map predicting Nova-dependent splicing regulation J Ule, G Stefani, A Mele, M Ruggiu, X Wang, B Taneri, T Gaasterland, ... Nature 444 (7119), 580-586, 2006 | 685 | 2006 |
TDP‐43 regulates its mRNA levels through a negative feedback loop YM Ayala, L De Conti, SE Avendańo‐Vázquez, A Dhir, M Romano, ... The EMBO journal 30 (2), 277-288, 2011 | 672 | 2011 |
Alternative splicing regulatory networks: functions, mechanisms, and evolution J Ule, BJ Blencowe Molecular cell 76 (2), 329-345, 2019 | 624 | 2019 |
Nova regulates brain-specific splicing to shape the synapse J Ule, A Ule, J Spencer, A Williams, JS Hu, M Cline, H Wang, T Clark, ... Nature genetics 37 (8), 844-852, 2005 | 606 | 2005 |
Hexanucleotide repeats in ALS/FTD form length-dependent RNA foci, sequester RNA binding proteins, and are neurotoxic YB Lee, HJ Chen, JN Peres, J Gomez-Deza, J Attig, M Štalekar, ... Cell reports 5 (5), 1178-1186, 2013 | 581 | 2013 |
Aberrant methylation of t RNA s links cellular stress to neuro‐developmental disorders S Blanco, S Dietmann, JV Flores, S Hussain, C Kutter, P Humphreys, ... The EMBO journal 33 (18), 2020-2039, 2014 | 569 | 2014 |
The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes D Blazek, J Kohoutek, K Bartholomeeusen, E Johansen, P Hulinkova, ... Genes & development 25 (20), 2158-2172, 2011 | 535 | 2011 |
NSun2-mediated cytosine-5 methylation of vault noncoding RNA determines its processing into regulatory small RNAs S Hussain, AA Sajini, S Blanco, S Dietmann, P Lombard, Y Sugimoto, ... Cell reports 4 (2), 255-261, 2013 | 525 | 2013 |
Direct competition between hnRNP C and U2AF65 protects the transcriptome from the exonization of Alu elements K Zarnack, J König, M Tajnik, I Martincorena, S Eustermann, I Stévant, ... Cell 152 (3), 453-466, 2013 | 504 | 2013 |
iCLIP: protein–RNA interactions at nucleotide resolution I Huppertz, J Attig, A D’Ambrogio, LE Easton, CR Sibley, Y Sugimoto, ... Methods 65 (3), 274-287, 2014 | 497 | 2014 |
Protein–RNA interactions: new genomic technologies and perspectives J König, K Zarnack, NM Luscombe, J Ule Nature Reviews Genetics 13 (2), 77-83, 2012 | 470 | 2012 |
Major shifts in glial regional identity are a transcriptional hallmark of human brain aging L Soreq, J Rose, E Soreq, J Hardy, D Trabzuni, MR Cookson, C Smith, ... Cell reports 18 (2), 557-570, 2017 | 396 | 2017 |
Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing MM Pradeepa, HG Sutherland, J Ule, GR Grimes, WA Bickmore PLoS genetics 8 (5), e1002717, 2012 | 385 | 2012 |
Molecular basis of UG-rich RNA recognition by the human splicing factor TDP-43 PJ Lukavsky, D Daujotyte, JR Tollervey, J Ule, C Stuani, E Buratti, ... Nature structural & molecular biology 20 (12), 1443-1449, 2013 | 380 | 2013 |
The SMAD2/3 interactome reveals that TGFβ controls m6A mRNA methylation in pluripotency A Bertero, S Brown, P Madrigal, A Osnato, D Ortmann, L Yiangou, ... Nature 555 (7695), 256-259, 2018 | 342 | 2018 |