| Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser Y Kang, XE Zhou, X Gao, Y He, W Liu, A Ishchenko, A Barty, TA White, ... Nature 523 (7562), 561-567, 2015 | 827 | 2015 |
| Cryo-EM structure of human rhodopsin bound to an inhibitory G protein Y Kang, O Kuybeda, PW de Waal, S Mukherjee, N Van Eps, P Dutka, ... Nature 558 (7711), 553-558, 2018 | 250 | 2018 |
| Structural basis of AMPK regulation by adenine nucleotides and glycogen X Li, L Wang, XE Zhou, J Ke, PW De Waal, X Gu, MH Tan, D Wang, D Wu, ... Cell research 25 (1), 50-66, 2015 | 186 | 2015 |
| Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors J Ke, H Ma, X Gu, A Thelen, JS Brunzelle, J Li, HE Xu, K Melcher Science advances 1 (6), e1500107, 2015 | 149 | 2015 |
| Structure and function of Norrin in assembly and activation of a Frizzled 4–Lrp5/6 complex J Ke, KG Harikumar, C Erice, C Chen, X Gu, L Wang, N Parker, Z Cheng, ... Genes & development 27 (21), 2305-2319, 2013 | 130 | 2013 |
| Structural basis for RNA recognition by a dimeric PPR-protein complex J Ke, RZ Chen, T Ban, XE Zhou, X Gu, MHE Tan, C Chen, Y Kang, ... Nature structural & molecular biology 20 (12), 1377-1382, 2013 | 112 | 2013 |
| An efficient and targeted gene integration system for high-level antibody expression Y Huang, Y Li, YG Wang, X Gu, Y Wang, BF Shen Journal of immunological methods 322 (1-2), 28-39, 2007 | 111 | 2007 |
| A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex H Ma, J Duan, J Ke, Y He, X Gu, TH Xu, H Yu, Y Wang, JS Brunzelle, ... Science advances 3 (6), e1601217, 2017 | 79 | 2017 |
| Wnt5a promotes Frizzled-4 signalosome assembly by stabilizing cysteine-rich domain dimerization ZJ DeBruine, J Ke, KG Harikumar, X Gu, P Borowsky, BO Williams, W Xu, ... Genes & development 31 (9), 916-926, 2017 | 63 | 2017 |
| Structure of a PLS-class pentatricopeptide repeat protein provides insights into mechanism of RNA recognition T Ban, J Ke, R Chen, X Gu, MHE Tan, XE Zhou, Y Kang, K Melcher, ... Journal of Biological Chemistry 288 (44), 31540-31548, 2013 | 60 | 2013 |
| Structural and functional study of D-glucuronyl C5-epimerase Y Qin, J Ke, X Gu, J Fang, W Wang, Q Cong, J Li, J Tan, JS Brunzelle, ... Journal of Biological Chemistry 290 (8), 4620-4630, 2015 | 54 | 2015 |
| Deconvoluting AMP-activated protein kinase (AMPK) adenine nucleotide binding and sensing X Gu, Y Yan, SJ Novick, A Kovach, D Goswami, J Ke, MHE Tan, L Wang, ... Journal of Biological Chemistry 292 (30), 12653-12666, 2017 | 52 | 2017 |
| Molecular modeling and affinity determination of scFv antibody: proper linker peptide enhances its activity X Gu, X Jia, J Feng, B Shen, Y Huang, S Geng, Y Sun, Y Wang, Y Li, ... Annals of biomedical engineering 38, 537-549, 2010 | 48 | 2010 |
| Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor α and … LK Golani, A Wallace-Povirk, SM Deis, J Wong, J Ke, X Gu, S Raghavan, ... Journal of medicinal chemistry 59 (17), 7856-7876, 2016 | 44 | 2016 |
| Structural basis of the Norrin-Frizzled 4 interaction G Shen, J Ke, Z Wang, Z Cheng, X Gu, Y Wei, K Melcher, HE Xu, W Xu Cell research 25 (9), 1078-1081, 2015 | 43 | 2015 |
| Binding activity difference of anti-CD20 scFv-Fc fusion protein derived from variable domain exchange SS Geng, J Feng, Y Li, Y Sun, X Gu, Y Huang, Y Wang, X Kang, H Chang, ... Cell Mol Immunol 3 (6), 439-443, 2006 | 32 | 2006 |
| Conformational heterogeneity of the allosteric drug and metabolite (ADaM) site in AMP-activated protein kinase (AMPK) X Gu, MD Bridges, Y Yan, PW de Waal, XE Zhou, KM Suino-Powell, ... Journal of Biological Chemistry 293 (44), 16994-17007, 2018 | 19 | 2018 |
| A highly sensitive non-radioactive activity assay for AMP-activated protein kinase (AMPK) Y Yan, X Gu, HE Xu, K Melcher Methods and protocols 1 (1), 3, 2017 | 7 | 2017 |
| Structured to reduce the mitogenicity of anti-CD3 antibody based on computer-guided molecular design M Lv, Y Li, M Yu, Y Sun, Z Lin, C Qiao, Q Luo, X Gu, Y Huang, J Feng, ... The International Journal of Biochemistry & Cell Biology 39 (6), 1142-1155, 2007 | 5 | 2007 |
| Human IgG1 Cgamma1 domain is crucial for the bioactivity of the engineered anti-CD20 antibodies S Geng, J Feng, Y Li, X Kang, Y Sun, X Gu, Y Huang, H Chang, BF Shen Cell Mol. Immunol 4 (2), 121-125, 2007 | 3 | 2007 |
Karsten MelcherVan Andel InstituteVerified email at vai.org
