High risk of patient self-inflicted lung injury in COVID-19 with frequently encountered spontaneous breathing patterns: a computational modelling study L Weaver, A Das, S Saffaran, N Yehya, TE Scott, M Chikhani, JG Laffey, ... Annals of intensive care 11, 1-8, 2021 | 70 | 2021 |
CRISPR-mediated reactivation of DKK3 expression attenuates TGF-β signaling in prostate cancer H Kardooni, E Gonzalez-Gualda, E Stylianakis, S Saffaran, J Waxman, ... Cancers 10 (6), 165, 2018 | 41 | 2018 |
Application and potential of artificial intelligence in neonatal medicine C Henry, S Saffaran, M Meeus, D Bates, D Van Laere, G Boylan, ... Seminars in Fetal and Neonatal Medicine 27 (5), 101346, 2022 | 29 | 2022 |
Utility of Driving Pressure and Mechanical Power to Guide Protective Ventilator Settings in Two Cohorts of Adult and Pediatric Patients With Acute Respiratory Distress Syndrome … S Saffaran, A Das, JG Hardman, JG Laffey, N Yehya, DG Bates Critical Care Medicine, 0 | 29* | |
High-fidelity computational simulation to refine strategies for lung-protective ventilation in paediatric acute respiratory distress syndrome S Saffaran, A Das, JG Hardman, N Yehya, DG Bates Intensive care medicine 45, 1055-1057, 2019 | 17 | 2019 |
In silico modeling of coronavirus disease 2019 acute respiratory distress syndrome: pathophysiologic insights and potential management implications A Das, S Saffaran, M Chikhani, TE Scott, M Laviola, N Yehya, JG Laffey, ... Critical care explorations 2 (9), e0202, 2020 | 15 | 2020 |
Computational simulation of virtual patients reduces dataset bias and improves machine learning-based detection of ARDS from noisy heterogeneous ICU datasets K Sharafutdinov, SJ Fritsch, M Iravani, PF Ghalati, S Saffaran, DG Bates, ... IEEE Open Journal of Engineering in Medicine and Biology, 2023 | 9 | 2023 |
Optimising respiratory support for early COVID-19 pneumonia: a computational modelling study L Weaver, A Das, S Saffaran, N Yehya, M Chikhani, TE Scott, JG Laffey, ... British Journal of Anaesthesia 128 (6), 1052-1058, 2022 | 6 | 2022 |
Modeling mechanical ventilation in silico—potential and pitfalls DM Hannon, S Mistry, A Das, S Saffaran, JG Laffey, BS Brook, ... Seminars in Respiratory and Critical Care Medicine 43 (03), 335-345, 2022 | 4 | 2022 |
Utilisation of prescription cannabinoids in different surgical cohorts in the United States: a population-based study A Sideris, H Zhong, C Cozowicz, J Poeran, SG Memtsoudis British Journal of Anaesthesia 128 (6), e341-e342, 2022 | 3 | 2022 |
Developing an artificial intelligence-based representation of a virtual patient model for real-time diagnosis of acute respiratory distress syndrome CS Barakat, K Sharafutdinov, J Busch, S Saffaran, DG Bates, JG Hardman, ... Diagnostics 13 (12), 2098, 2023 | 2 | 2023 |
A computational cardiopulmonary physiology simulator accurately predicts individual patient responses to changes in mechanical ventilator settings S Mistry, BS Brook, S Saffaran, M Chikhani, DM Hannon, JG Laffey, ... 2022 44th Annual International Conference of the IEEE Engineering in …, 2022 | 2 | 2022 |
Validation of at-the-bedside formulae for estimating ventilator driving pressure during airway pressure release ventilation using computer simulation S Mistry, A Das, S Saffaran, N Yehya, TE Scott, M Chikhani, JG Laffey, ... Respiratory Research 23 (1), 101, 2022 | 1 | 2022 |
Inhaled sGC modulator can lower pH in patients with COPD without deteriorating oxygenation S Saffaran, W Wang, A Das, W Schmitt, EM Becker‐Pelster, JG Hardman, ... CPT: pharmacometrics & systems pharmacology 7 (8), 491-498, 2018 | 1 | 2018 |
Development and validation of a computational simulator for pediatric acute respiratory distress syndrome patients S Saffaran, A Das, JG Hardman, N Yehya, DG Bates 2017 39th Annual International Conference of the IEEE Engineering in …, 2017 | 1 | 2017 |
Correction and standardisation of lung oscillometry techniques using parameter inference: A study group report BS Brook, GR Douglas, OE Jensen, S Mistry, SK Nath, MJ Russell, ... arXiv preprint arXiv:2403.04621, 2024 | | 2024 |
Digital Twins of Acute Hypoxemic Respiratory Failure Patients Suggest a Mechanistic Basis for Success and Failure of Noninvasive Ventilation L Weaver, H Shamohammadi, S Saffaran, R Tonelli, M Laviola, JG Laffey, ... Critical Care Medicine, 10.1097, 2024 | | 2024 |
An in-silico porcine model of phosgene-induced lung injury predicts clinically relevant benefits from application of continuous positive airway pressure up to 8 h post exposure S Mistry, TE Scott, B Jugg, R Perrott, S Saffaran, DG Bates Toxicology Letters 391, 45-54, 2024 | | 2024 |
Why reduced inspiratory pressure could determine success of non-invasive ventilation in acute hypoxic respiratory failure L Weaver, S Saffaran, M Chikhani, JG Laffey, TE Scott, L Camporota, ... 2022 44th Annual International Conference of the IEEE Engineering in …, 2022 | | 2022 |
In-silico modeling of COVID-19 ARDS: pathophysiological insights and potential management implications A Das, S Saffaran, M Chikhani, TE Scott, M Laviola, N Yehya, JG Laffey, ... medRxiv, 2020.07. 21.20158659, 2020 | | 2020 |