| Non-classical transpeptidases yield insight into new antibacterials P Kumar, A Kaushik, EP Lloyd, SG Li, R Mattoo, NC Ammerman, DT Bell, ... Nature chemical biology 13 (1), 54-61, 2017 | 127 | 2017 |
| Inhibition of innate immune cytosolic surveillance by an M. tuberculosis phosphodiesterase RJ Dey, B Dey, Y Zheng, LS Cheung, J Zhou, D Sayre, P Kumar, H Guo, ... Nature chemical biology 13 (2), 210-217, 2017 | 88 | 2017 |
| Second-generation IL-2 receptor-targeted diphtheria fusion toxin exhibits antitumor activity and synergy with anti–PD-1 in melanoma LS Cheung, J Fu, P Kumar, A Kumar, ME Urbanowski, EA Ihms, ... Proceedings of the National Academy of Sciences 116 (8), 3100-3105, 2019 | 63 | 2019 |
| Mycobacterium abscessus l,d-Transpeptidases Are Susceptible to Inactivation by Carbapenems and Cephalosporins but Not Penicillins P Kumar, V Chauhan, JRA Silva, J Lameira, FB d'Andrea, SG Li, SL Ginell, ... Antimicrobial agents and chemotherapy 61 (10), 10.1128/aac. 00866-17, 2017 | 63 | 2017 |
| Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase LdtMt2 by biapenem and tebipenem MA Bianchet, YH Pan, LAB Basta, H Saavedra, EP Lloyd, P Kumar, ... BMC biochemistry 18, 1-14, 2017 | 48 | 2017 |
| Role of a non-canonical surface of Rad6 in ubiquitin conjugating activity P Kumar, P Magala, KR Geiger-Schuller, A Majumdar, JR Tolman, ... Nucleic acids research 43 (18), 9039-9050, 2015 | 35 | 2015 |
| Crystal structure analysis of icosahedral lumazine synthase from Salmonella typhimurium, an antibacterial drug target P Kumar, M Singh, S Karthikeyan Acta Crystallographica Section D: Biological Crystallography 67 (2), 131-139, 2011 | 22 | 2011 |
| Structure of the yeast Bre1 RING domain P Kumar, C Wolberger Proteins: Structure, Function, and Bioinformatics 83 (6), 1185-1190, 2015 | 21 | 2015 |
| Mutation in an unannotated protein confers carbapenem resistance in Mycobacterium tuberculosis P Kumar, A Kaushik, DT Bell, V Chauhan, F Xia, RL Stevens, ... Antimicrobial agents and chemotherapy 61 (3), 10.1128/aac. 02234-16, 2017 | 20 | 2017 |
| Recent advances with Treg depleting fusion protein toxins for cancer immunotherapy P Kumar, A Kumar, S Parveen, JR Murphy, W Bishai Immunotherapy 11 (13), 1117-1128, 2019 | 18 | 2019 |
| LdtMav2, a nonclassical transpeptidase and susceptibility of Mycobacterium avium to carbapenems R Mattoo, EP Lloyd, A Kaushik, P Kumar, JL Brunelle, CA Townsend, ... Future microbiology 12 (7), 595-607, 2017 | 17 | 2017 |
| Potential anti‐bacterial drug target: Structural characterization of 3,4‐dihydroxy‐2‐butanone‐4‐phosphate synthase from Salmonella typhimurium LT2 P Kumar, M Singh, R Gautam, S Karthikeyan Proteins: Structure, Function, and Bioinformatics 78 (16), 3292-3303, 2010 | 15 | 2010 |
| The crystal structure reveals the molecular mechanism of bifunctional 3, 4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II (Rv1415) from Mycobacterium tuberculosis M Singh, P Kumar, S Yadav, R Gautam, N Sharma, S Karthikeyan Acta Crystallographica Section D: Biological Crystallography 69 (9), 1633-1644, 2013 | 14 | 2013 |
| Zooming in on common immune evasion mechanisms of pathogens in phagolysosomes: potential broad-spectrum therapeutic targets against infectious diseases A Selvapandiyan, N Puri, P Kumar, A Alam, NZ Ehtesham, G Griffin, ... FEMS Microbiology Reviews 47 (1), fuac041, 2023 | 11 | 2023 |
| Structural basis for pH dependent monomer-dimer transition of 3, 4-dihydroxy 2-butanone-4-phosphate synthase domain from M. tuberculosis M Singh, P Kumar, S Karthikeyan Journal of Structural Biology, 2011 | 8 | 2011 |
| The linker domain of the initiator DnaA contributes to its ATP binding and membrane association in E. coli chromosomal replication Y Hou, P Kumar, M Aggarwal, F Sarkari, KM Wolcott, DK Chattoraj, ... Science Advances 8 (40), eabq6657, 2022 | 7 | 2022 |
| A nucleotide-dependent oligomerization of the Escherichia coli replication initiator DnaA requires residue His136 for remodeling of the chromosomal origin R Saxena, CB Stanley, P Kumar, MJ Cuneo, D Patil, J Jha, KL Weiss, ... Nucleic Acids Research 48 (1), 200-211, 2020 | 5 | 2020 |
| Glby, Encoded by MAB_3167c, Is Required for In Vivo Growth of Mycobacteroides abscessus and Exhibits Mild β-Lactamase Activity C Galanis, EC Maggioncalda, P Kumar, G Lamichhane Journal of bacteriology 204 (5), e00046-22, 2022 | 4 | 2022 |
| Repurposing of carbapenems for the treatment of drug-resistant tuberculosis P Kumar, UB Singh, G Lamichhane, E Story-Roller Mycobacterium Tuberculosis: Molecular Infection Biology, Pathogenesis …, 2019 | 3 | 2019 |
| Inhibition of host PARP1 contributes to the anti-inflammatory and antitubercular activity of pyrazinamide S Krug, M Gupta, P Kumar, L Feller, EA Ihms, BG Kang, G Srikrishna, ... Nature communications 14 (1), 8161, 2023 | 1 | 2023 |
Gyanu LamichhaneAssociate Professor, Infectious Diseases, Johns Hopkins UniversityVerified email at jhu.edu
