Detection of BRAF V600 mutations in metastatic melanoma: comparison of the Cobas 4800 and Sanger sequencing assays K Qu, Q Pan, X Zhang, L Rodriguez, K Zhang, H Li, A Ho, H Sanders, ... The Journal of Molecular Diagnostics 15 (6), 790-795, 2013 | 74 | 2013 |
Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease KD Alysandratos, SJ Russo, A Petcherski, EP Taddeo, R Acín-Pérez, ... Cell Reports 36 (9), 109636, 2021 | 67 | 2021 |
Global Gene Expression Analysis in an in vitro Fibroblast Model of Idiopathic Pulmonary Fibrosis Reveals Potential Role for CXCL14/CXCR4 LR Rodriguez, M Emblom-Callahan, M Chhina, S Bui, B Aljeburry, ... Scientific Reports 8 (1), 3983, 2018 | 35 | 2018 |
Curcumin induced oxidative stress attenuation by N-acetylcysteine co-treatment: a fibroblast and epithelial cell in-vitro study in idiopathic pulmonary fibrosis LR Rodriguez, SN Bui, RT Beuschel, E Ellis, EM Liberti, MK Chhina, ... Molecular Medicine 25 (1), 27, 2019 | 24 | 2019 |
The common ABCA3E292V variant disrupts AT2 cell quality control and increases susceptibility to lung injury and aberrant remodeling Y Tomer, J Wambach, L Knudsen, M Zhao, LR Rodriguez, A Murthy, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 321 (2 …, 2021 | 18 | 2021 |
Disruption of proteostasis causes IRE1 mediated reprogramming of alveolar epithelial cells J Katzen, L Rodriguez, Y Tomer, A Babu, M Zhao, A Murthy, P Carson, ... Proceedings of the National Academy of Sciences 119 (43), e2123187119, 2022 | 10 | 2022 |
Chronic Expression of a Clinical SFTPC Mutation Causes Murine Lung Fibrosis with Idiopathic Pulmonary Fibrosis Features L Rodriguez, Y Tomer, P Carson, T Dimopoulos, M Zhao, K Chavez, ... American Journal of Respiratory Cell and Molecular Biology 68 (4), 358-365, 2023 | 9 | 2023 |
PGF2α signaling drives fibrotic remodeling and fibroblast population dynamics in mice LR Rodriguez, SY Tang, WR Barboza, A Murthy, Y Tomer, TQ Cai, S Iyer, ... JCI insight 8 (24), 2023 | 2* | 2023 |
Alveolar Type 2 Epithelial Cell Quality Control Responses to Pulmonary Fibrosis Related SFTPC Mutations Are Dysfunctional And Substrate Specific MF Beers, L Rodriguez, A Hawkins, SJ Russo, Y Tomer, S Mulugeta, ... The FASEB Journal 34 (S1), 1-1, 2020 | 2 | 2020 |
Epithelial metabolic stress in IPF: Identifying intervention strategies using a preclinical murine SftpcI73T model of lung fibrosis L Rodriguez, A Murthy, Y Tomer, T Dimopoulos, K Chavez, M Beers European Respiratory Journal 62 (suppl 67), 2023 | 1 | 2023 |
Does Cytochrome p450 3A4 Catalyzed Metabolism in Pulmonary Fibroblasts Contribute to Oxidative Stress in Idiopathic Pulmonary Fibrosis? L Rodriguez, R Beuschel, E Ellis, S Bui, SD Nathan, GM Grant C72. PULMONARY FIBROSIS: MECHANISMS AND MODELS, A5767-A5767, 2018 | 1 | 2018 |
Emerging Evidence for BAX-Inhibitor-1 (BI-1) in Differential Unfolded Protein Response (UPR) in Idiopathic Pulmonary Fibrosis (IPF) Fibroblasts S Bui, A Doane, L Rodriguez, SD Nathan, GM Grant, G Mason AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 197, 2018 | 1 | 2018 |
A Novel Role For Thymosin Beta4 In Lung Fibrosis Via Tgf-beta Mediated Epithelial Mesenchymal Transition L Rodriguez, SD Nathan, M Chinna, M Leema, G Grant American Journal of Respiratory and Critical Care Medicine 191, 2015 | 1 | 2015 |
Checkpoint Inhibitor Pathway Dysfunction in Pulmonary Fibrosis A Murthy, LR Rodriguez, W Roque Barboza, S Bui, C Cooper, K Chavez, ... B28. LUNGS THORUGH TIME: EXPLORING LUNG AGING, A3213-A3213, 2024 | | 2024 |
Alveolar Epithelial Mitochondrial Impairments in Pulmonary Fibrosis: The Role of AMPK Signaling KD Alysandratos, LR Rodriguez, K Minakin, A Murthy, Y Tomer, K Chavez, ... C28. MORE THAN MEET THE EYE: NOVEL INSIGHTS IN IPF PATHOGENESIS, A5204-A5204, 2024 | | 2024 |
Aberrant Alveolar Epithelial Cells Alter the Alveolar Mesenchyme to Promote Fibrosis in a Clinical Sftpc Mutation Model of Lung Fibrosis ET Hoffman, W Roque Barboza, LR Rodriguez, A Murthy, R Dherwani, ... C28. MORE THAN MEET THE EYE: NOVEL INSIGHTS IN IPF PATHOGENESIS, A5197-A5197, 2024 | | 2024 |
A Novel Fibroblast Population Supports Repair of the Alveolar Niche: Insights From a Preclinical Mouse Model of Idiopathic Pulmonary Fibrosis W Roque Barboza, LR Rodriguez, A Murthy, ET Hoffman, J Katzen, ... B98. HEALING LUNGS: NAVIGATING THE PATHWAYS OF LUNG REPAIR, A4727-A4727, 2024 | | 2024 |
Transitional AT2 Derived Lactate Promotes Alveolar Niche Dysfunction in the SftpcI73TMurine Model of IPF LR Rodriguez, W Roque Barboza, A Murthy, Y Tomer, S Bui, C Cooper, ... C98. ENERGIZING THE LUNG: MITOCHONDRIA AND METABOLIC PATHWAYS, A6647-A6647, 2024 | | 2024 |
Nuclear Factor E2-related Factor 1 (Nrf1) and ER-associated Degradation (ERAD) Coordinate the Proteasome Response to Surfactant Protein C Aggregates in Alveolar Epithelial Cells S Bui, LR Rodriguez, W Roque Barboza, C Cooper, K Chavez, A Murthy, ... A72. EPITHELIAL CELLS: KEY CULPRITS IN PULMONARY FIBROSIS, A2573-A2573, 2024 | | 2024 |
Aging Alters Alveolar Niche Crosstalk and Impairs Alveolar Type II Cell Progenitor Function in a Murine Model of Pulmonary Fibrosis L Rodriguez, WB Roque, A Murthy, Y Tomer, C Cooper, K Chavez, ... ERJ Open Research 10 (suppl 14), 2024 | | 2024 |