Epigenetic and neurological effects and safety of high-dose nicotinamide in patients with Friedreich's ataxia: an exploratory, open-label, dose-escalation study V Libri, C Yandim, S Athanasopoulos, N Loyse, T Natisvili, PP Law, ... The Lancet 384 (9942), 504-513, 2014 | 157 | 2014 |
Sexual dimorphism in mammalian autosomal gene regulation is determined not only by Sry but by sex chromosome complement as well PJ Wijchers, C Yandim, E Panousopoulou, M Ahmad, N Harker, ... Developmental cell 19 (3), 477-484, 2010 | 133 | 2010 |
Heterochromatinization induced by GAA-repeat hyperexpansion in Friedreich's ataxia can be reduced upon HDAC inhibition by vitamin B3 PK Chan, R Torres, C Yandim, PP Law, S Khadayate, M Mauri, C Grosan, ... Human molecular genetics 22 (13), 2662-2675, 2013 | 95 | 2013 |
Gene regulation and epigenetics in Friedreich's ataxia C Yandim, T Natisvili, R Festenstein Journal of neurochemistry 126, 21-42, 2013 | 81 | 2013 |
Expression dynamics of repetitive DNA in early human embryonic development C Yandım, G Karakülah BMC genomics 20, 1-16, 2019 | 36 | 2019 |
A systematic molecular and pharmacologic evaluation of AKT inhibitors reveals new insight into their biological activity E Kostaras, T Kaserer, G Lazaro, SF Heuss, A Hussain, P Casado, ... British Journal of Cancer 123 (4), 542-555, 2020 | 28 | 2020 |
TEffectR: an R package for studying the potential effects of transposable elements on gene expression with linear regression model G Karakülah, N Arslan, C Yandım, A Suner PeerJ 7, e8192, 2019 | 23 | 2019 |
Dysregulated expression of repetitive DNA in ER+/HER2-breast cancer C Yandım, G Karakülah Cancer Genetics 239, 36-45, 2019 | 15 | 2019 |
Transcriptional activation of Pericentromeric Satellite repeats and disruption of Centromeric clustering upon proteasome inhibition T Natisvili, C Yandim, R Silva, G Emanuelli, F Krueger, S Nageshwaran, ... PLoS One 11 (11), e0165873, 2016 | 9 | 2016 |
Signature changes in the expressions of protein-coding genes, lncRNAs, and repeat elements in early and late cellular senescence G Karakülah, C Yandim Turkish Journal of Biology 44 (6), 356-370, 2020 | 8 | 2020 |
Characterization of cisplatin loaded hydrophilic glycol chitosan modified eumelanin nanoparticles for potential controlled-release application A Atik, T Günal, PA Bozkurt, SN Köse, B Alp, C Yandım, NM Kaleli, ... Journal of Drug Delivery Science and Technology 84, 104440, 2023 | 5 | 2023 |
Comparative molecular dynamics analyses on PIK3CA hotspot mutations with PI3Kα specific inhibitors and ATP M Menteş, BB Karakuzulu, GB Uçar, C Yandım Computational Biology and Chemistry, 107726, 2022 | 3 | 2022 |
Identification of differentially expressed genomic repeats in primary hepatocellular carcinoma and their potential links to biological processes and survival G Karakülah, C Yandim Turkish Journal of Biology 45 (5), 599-612, 2021 | 1 | 2021 |
In silico drug screen reveals potential competitive MTHFR inhibitors for clinical repurposing N Keske, B Özay, EY Tükel, M Menteş, C Yandım Journal of Biomolecular Structure and Dynamics 41 (21), 11818-11831, 2023 | | 2023 |
Identification of PPA1 inhibitor candidates for potential repurposing in cancer medicine M Menteş, C Yandım Journal of Cellular Biochemistry 124 (10), 1646-1663, 2023 | | 2023 |
Thyroid hormone T3 augments the cytotoxicity of sorafenib in Huh7 hepatocellular carcinoma cells by suppressing AKT expression S Uyulgan, SN Köse, A Kıpçak, Y Başkan, G Dağlar, ZF Karagonlar, ... Journal of Cancer Research and Therapeutics, 2023 | | 2023 |
Repeat expression is linked to patient survival and exhibits single nucleotide variation in pancreatic cancer revealing LTR70: r. 879A> G C Yandım, G Karakülah Gene 822, 146344, 2022 | | 2022 |
Nicotinamide given once daily is more effective than twice daily at increasing frataxin expression in Friedreich's ataxia S Nageshwaran, S Athanasopoulos, C Georgiadou, C Yandim, T Natisvili, ... MOVEMENT DISORDERS 30, S363-S363, 2015 | | 2015 |
EPIGENETICS, EPIGENOMICS, AND HUMAN DISEASE A Ramesh, C Yandim, T Natisvili, M Mauri, PP Law, JPK Chan, SU Lewis, ... Genomic Medicine: Principles and Practice, 39, 2014 | | 2014 |
Heterochromatin effects in Friedreich's ataxia and sexual dimorphism C Yandim Imperial College London, 2012 | | 2012 |