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Falak Sher
Falak Sher
Assistant Professor, Columbia University New York
Verified email at cumc.columbia.edu
Title
Cited by
Cited by
Year
BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis
MC Canver, EC Smith, F Sher, L Pinello, NE Sanjana, O Shalem, ...
Nature 527 (7577), 192-197, 2015
8862015
Direct promoter repression by BCL11A controls the fetal to adult hemoglobin switch
N Liu, VV Hargreaves, Q Zhu, JV Kurland, J Hong, W Kim, F Sher, ...
Cell 173 (2), 430-442. e17, 2018
3842018
Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin
T Masuda, X Wang, M Maeda, MC Canver, F Sher, APW Funnell, C Fisher, ...
Science 351 (6270), 285-289, 2016
3222016
Differentiation of neural stem cells into oligodendrocytes: involvement of the polycomb group protein Ezh2
F Sher, R Rößler, N Brouwer, V Balasubramaniyan, E Boddeke, S Copray
Stem cells 26 (11), 2875-2883, 2008
2092008
Rational targeting of a NuRD subcomplex guided by comprehensive in situ mutagenesis
F Sher, M Hossain, D Seruggia, VAC Schoonenberg, Q Yao, P Cifani, ...
Nature genetics 51 (7), 1149-1159, 2019
922019
Epigenetic mechanisms facilitating oligodendrocyte development, maturation, and aging
S Copray, JL Huynh, F Sher, P Casaccia‐Bonnefil, E Boddeke
Glia 57 (15), 1579-1587, 2009
812009
Dynamic changes in Ezh2 gene occupancy underlie its involvement in neural stem cell self-renewal and differentiation towards oligodendrocytes
F Sher, E Boddeke, M Olah, S Copray
PloS one 7 (7), e40399, 2012
802012
Ezh2 expression in astrocytes induces their dedifferentiation toward neural stem cells
F Sher, E Boddeke, S Copray
Cellular Reprogramming (Formerly" Cloning and Stem Cells") 13 (1), 1-6, 2011
652011
An erythroid-specific ATP2B4 enhancer mediates red blood cell hydration and malaria susceptibility
S Lessard, ES Gatof, M Beaudoin, PG Schupp, F Sher, A Ali, S Prehar, ...
The Journal of clinical investigation 127 (8), 3065-3074, 2017
622017
Oligodendrocyte differentiation and implantation: new insights for remyelinating cell therapy
F Sher, V Balasubramaniyan, E Boddeke, S Copray
Current opinion in neurology 21 (5), 607-614, 2008
612008
Strict in vivo specificity of the Bcl11a erythroid enhancer
EC Smith, S Luc, DM Croney, MB Woodworth, LC Greig, Y Fujiwara, ...
Blood, The Journal of the American Society of Hematology 128 (19), 2338-2342, 2016
462016
Bioluminescence imaging of Olig2-neural stem cells reveals improved engraftment in a demyelination mouse model
F Sher, G van Dam, E Boddeke, S Copray
Stem Cells 27 (7), 1582-1591, 2009
462009
Intraventricularly injected Olig2-NSCs attenuate established relapsing–remitting EAE in mice
F Sher, S Amor, W Gerritsen, D Baker, SL Jackson, E Boddeke, S Copray
Cell transplantation 21 (9), 1883-1897, 2012
402012
CRISPR-SURF: discovering regulatory elements by deconvolution of CRISPR tiling screen data
JY Hsu, CP Fulco, MA Cole, MC Canver, D Pellin, F Sher, R Farouni, ...
Nature methods 15 (12), 992-993, 2018
322018
CRISPRO: identification of functional protein coding sequences based on genome editing dense mutagenesis
VAC Schoonenberg, MA Cole, Q Yao, C Macias-Treviño, F Sher, ...
Genome biology 19, 1-19, 2018
312018
Crispr-Cas9 saturating mutagenesis reveals an achilles heel in the BCL11A erythroid enhancer for fetal hemoglobin induction (by Genome Editing)
DE Bauer, MC Canver, EC Smith, F Sher, L Pinello, NE Sanjana, ...
Blood 126 (23), 638, 2015
72015
Rö ssler
F Sher
R., Brouwer, N., Balasubramaniyan, V., Boddeke, E., and Copray, S, 2875-2883, 2008
72008
Fetal hemoglobin (HbF) silencer BCL11A acts through a novel DNA-motif in the gamma-globin promoters, simplifying the model for hemoglobin switching
N Liu, VV Hargreaves, J Hong, W Kim, J Kurland, Q Zhu, F Sher, ...
Blood 130, 283, 2017
32017
An Essential Erythroid-Specific Enhancer of ATP2B4 Associated with Red Blood Cell Traits and Malaria Susceptibility
EN Stern, S Lessard, PG Schupp, F Sher, G Lettre, DE Bauer
Blood, The Journal of the American Society of Hematology 128 (22), 1250-1250, 2016
22016
Rational Targeting of a NuRD Sub-Complex for Fetal Hemoglobin Induction Following Comprehensive in Situ Mutagenesis
M Hossain, F Sher, D Seruggia, V Schoonenberg, MA Cole, P Cifani, ...
Blood 132, 2342, 2018
12018
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