De novo design of a fluorescence-activating β-barrel J Dou, AA Vorobieva, W Sheffler, LA Doyle, H Park, MJ Bick, B Mao, ... Nature 561 (7724), 485-491, 2018 | 320 | 2018 |
De novo design of transmembrane β barrels AA Vorobieva, P White, B Liang, JE Horne, AK Bera, CM Chow, S Gerben, ... Science 371 (6531), eabc8182, 2021 | 97 | 2021 |
Balancing specificity and promiscuity in enzyme evolution: multidimensional activity transitions in the alkaline phosphatase superfamily B Van Loo, CD Bayer, G Fischer, S Jonas, E Valkov, MF Mohamed, ... Journal of the American Chemical Society 141 (1), 370-387, 2018 | 40 | 2018 |
Incorporation of sensing modalities into de novo designed fluorescence-activating proteins JC Klima, LA Doyle, JD Lee, M Rappleye, LA Gagnon, MY Lee, EP Barros, ... Nature communications 12 (1), 856, 2021 | 39 | 2021 |
Improving the efficiency of ligand-binding protein design with molecular dynamics simulations EP Barros, JM Schiffer, A Vorobieva, J Dou, D Baker, RE Amaro Journal of chemical theory and computation 15 (10), 5703-5715, 2019 | 23 | 2019 |
Escherichia coli D-malate dehydrogenase, a generalist enzyme active in the leucine biosynthesis pathway AA Vorobieva, MS Khan, P Soumillion Journal of Biological Chemistry 289 (42), 29086-29096, 2014 | 21 | 2014 |
Principles and methods in computational membrane protein design AA Vorobieva Journal of Molecular Biology 433 (20), 167154, 2021 | 12 | 2021 |
Design and optimization of enzymatic activity in a de novo β‐barrel scaffold Y Kipnis, AO Chaib, AA Vorobieva, G Cai, G Reggiano, B Basanta, ... Protein Science 31 (11), e4405, 2022 | 10 | 2022 |
B-Cell Epitope Mapping of TprC and TprD Variants of Treponema pallidum Subspecies Informs Vaccine Development for Human Treponematoses B Molini, MC Fernandez, C Godornes, A Vorobieva, SA Lukehart, ... Frontiers in Immunology 13, 862491, 2022 | 10 | 2022 |
Treponema pallidum subsp. pallidum with an Artificially impaired TprK antigenic variation system is attenuated in the Rabbit model of syphilis E Romeis, NAP Lieberman, B Molini, LC Tantalo, B Chung, Q Phung, ... PLoS Pathogens 19 (3), e1011259, 2023 | 6 | 2023 |
Evolutionary adaptation of the protein folding pathway for secretability D Smets, A Tsirigotaki, JH Smit, S Krishnamurthy, AG Portaliou, ... The EMBO Journal 41 (23), e111344, 2022 | 6 | 2022 |
Bacterial expression and protein purification of mini-fluorescence-activating proteins JC Klima, CM Chow, J Dou, AA Vorobieva, L Carter, D Baker | 5 | 2021 |
Validation of de novo designed water-soluble and transmembrane proteins by in silico folding and melting AM Hermosilla, C Berner, S Ovchinnikov, AA Vorobieva bioRxiv, 2023.06. 06.543955, 2023 | 4 | 2023 |
De novo design of diverse small molecule binders and sensors using Shape Complementary Pseudocycles L An, M Said, L Tran, S Majumder, I Goreshnik, GR Lee, D Juergens, ... bioRxiv, 2023 | 3 | 2023 |
Sculpting conducting nanopore size and shape through de novo protein design S Berhanu, S Majumder, T Müntener, J Whitehouse, C Berner, AK Bera, ... bioRxiv, 2023 | 3 | 2023 |
Evolutionary adaptation of the folding pathway for secretability D Smets, A Tsirigotaki, JH Smit, S Krishnamurthy, AG Portaliou, ... bioRxiv, 2022.04. 03.486881, 2022 | 2 | 2022 |
Rationale in Custom Design of Transmembrane β-Barrel Pores AA Vorobieva Transmembrane β-Barrel Proteins: Methods and Protocols, 345-366, 2024 | | 2024 |
ProteinMPNN Recovers Complex Sequence Properties of Transmembrane β-barrels M Dolorfino, R Samanta, A Vorobieva bioRxiv, 2024.01. 16.575764, 2024 | | 2024 |
Validation of de novo designed water-soluble and transmembrane β-barrels by in silico folding and melting. A Martin, C Berner, S Ovchinnikov, AA Vorobieva Protein Science, 2024 | | 2024 |
Treponema pallidum subsp. pallidum with an Artificially Impaired TprK Antigenic Variation System is Attenuated in the Rabbit Model of Syphilis L Giacani, B Chung, AL Greninger, N Lieberman, B Molini, Q Phung, ... SEXUALLY TRANSMITTED DISEASES 51 (1), S362-S363, 2024 | | 2024 |