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Edward Eckels
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S-glutathionylation of cryptic cysteines enhances titin elasticity by blocking protein folding
J Alegre-Cebollada, P Kosuri, D Giganti, E Eckels, JA Rivas-Pardo, ...
Cell 156 (6), 1235-1246, 2014
2282014
Work done by titin protein folding assists muscle contraction
JA Rivas-Pardo, EC Eckels, I Popa, P Kosuri, WA Linke, JM Fernández
Cell reports 14 (6), 1339-1347, 2016
1962016
A HaloTag anchored ruler for week-long studies of protein dynamics
I Popa, JA Rivas-Pardo, EC Eckels, DJ Echelman, CL Badilla, ...
Journal of the American Chemical Society 138 (33), 10546-10553, 2016
1392016
The effect of CD47 modified polymer surfaces on inflammatory cell attachment and activation
SJ Stachelek, MJ Finley, IS Alferiev, F Wang, RK Tsai, EC Eckells, ...
Biomaterials 32 (19), 4317-4326, 2011
862011
The work of titin protein folding as a major driver in muscle contraction
EC Eckels, R Tapia-Rojo, JA Rivas-Pardo, JM Fernández
Annual review of physiology 80, 327-351, 2018
822018
Ephemeral states in protein folding under force captured with a magnetic tweezers design
R Tapia-Rojo, EC Eckels, JM Fernández
Proceedings of the National Academy of Sciences 116 (16), 7873-7878, 2019
722019
Trigger factor chaperone acts as a mechanical foldase
S Haldar, R Tapia-Rojo, EC Eckels, J Valle-Orero, JM Fernandez
Nature communications 8 (1), 668, 2017
722017
The mechanical power of titin folding
EC Eckels, S Haldar, R Tapia-Rojo, JA Rivas-Pardo, JM Fernández
Cell reports 27 (6), 1836-1847. e4, 2019
712019
Protein folding modulates the chemical reactivity of a Gram-positive adhesin
A Alonso-Caballero, DJ Echelman, R Tapia-Rojo, S Haldar, EC Eckels, ...
Nature Chemistry 13 (2), 172-181, 2021
362021
The elastic free energy of a tandem modular protein under force
J Valle-Orero, EC Eckels, G Stirnemann, I Popa, R Berkovich, ...
Biochemical and biophysical research communications 460 (2), 434-438, 2015
282015
Proteins breaking bad: A free energy perspective
J Valle-Orero, R Tapia-Rojo, EC Eckels, JA Rivas-Pardo, I Popa, ...
The journal of physical chemistry letters 8 (15), 3642-3647, 2017
242017
Prevention of polyurethane oxidative degradation with phenolic antioxidants covalently attached to the hard segments: Structure–function relationships
SJ Stachelek, I Alferiev, M Ueda, EC Eckels, KT Gleason, RJ Levy
Journal of Biomedical Materials Research Part A 94 (3), 751-759, 2010
192010
DsbA is a redox-switchable mechanical chaperone
EC Eckels, D Chaudhuri, S Chakraborty, DJ Echelman, S Haldar
Chemical Science 12 (33), 11109-11120, 2021
102021
DsbA is a switchable mechanical chaperone
S Haldar, EC Eckels, DJ Echelman, JA Rivas-Pardo, JM Fernandez
BioRxiv, 310169, 2018
52018
Work done by titin protein folding assists muscle contraction. Cell Rep 14: 1339–1347
JA Rivas-Pardo, EC Eckels, I Popa, P Kosuri, WA Linke, JM Fernandez
52016
The science of stretching: Mechanical anisotropy in titin ig domains
EC Eckels, JA Rivas-Pardo, J Valle-Orero, I Popa, JM Fernandez
Biophysical Journal 110 (3), 393a, 2016
42016
Disulfide bonding in the contractile work of titin
JAR Pardo, E Eckels, J Valle-Orero, JM Fernadez
Biophysical Journal 112 (3), 456a, 2017
32017
Protein folding modulates the adhesion strategy of Gram positive pathogens
A Alonso-Caballero, DJ Echelman, R Tapia-Rojo, S Haldar, EC Eckels, ...
bioRxiv, 743393, 2019
12019
Disulfide bonds: the power switches of elastic proteins
EC Eckels, S Haldar, R Tapia-Rojo, JA Rivas Pardo, JM Fernández
bioRxiv, 383711, 2018
12018
Real-time Detection of Thiol Chemistry in Single Proteins
EC Eckels, DJ Echelman, JA Rivas-Pardo, JM Fernández
Oxidative Folding of Proteins: Basic Principles, Cellular Regulation and …, 2018
12018
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