Gioacchino Natoli
Gioacchino Natoli
Humanitas University (Hunimed) - Milan / IEO (European Institute of Oncology) - Milan
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TitleCited byYear
Macrophage activation and polarization: nomenclature and experimental guidelines
PJ Murray, JE Allen, SK Biswas, EA Fisher, DW Gilroy, S Goerdt, ...
Immunity 41 (1), 14-20, 2014
Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IκB kinase
A Rossi, P Kapahi, G Natoli, T Takahashi, Y Chen, M Karin, MG Santoro
Nature 403 (6765), 103, 2000
Transcriptional regulation of macrophage polarization: enabling diversity with identity
T Lawrence, G Natoli
Nature reviews immunology 11 (11), 750, 2011
IKK-γ is an essential regulatory subunit of the IκB kinase complex
DM Rothwarf, E Zandi, G Natoli, M Karin
Nature 395 (6699), 297, 1998
The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing
F De Santa, MG Totaro, E Prosperini, S Notarbartolo, G Testa, G Natoli
Cell 130 (6), 1083-1094, 2007
p38-Dependent marking of inflammatory genes for increased NF-κB recruitment
S Saccani, S Pantano, G Natoli
Nature immunology 3 (1), 69, 2002
The human Toll signaling pathway: divergence of nuclear factor κB and JNK/SAPK activation upstream of tumor necrosis factor receptor–associated factor 6 (TRAF6)
M Muzio, G Natoli, S Saccani, M Levrero, A Mantovani
Journal of Experimental Medicine 187 (12), 2097-2101, 1998
Transcriptional regulation via the NF-κB signaling module
A Hoffmann, G Natoli, G Ghosh
Oncogene 25 (51), 6706, 2006
A large fraction of extragenic RNA pol II transcription sites overlap enhancers
F De Santa, I Barozzi, F Mietton, S Ghisletti, S Polletti, BK Tusi, H Muller, ...
PLoS biology 8 (5), e1000384, 2010
Trained immunity: a program of innate immune memory in health and disease
MG Netea, LAB Joosten, E Latz, KHG Mills, G Natoli, HG Stunnenberg, ...
Science 352 (6284), aaf1098, 2016
Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages
S Ghisletti, I Barozzi, F Mietton, S Polletti, F De Santa, E Venturini, ...
Immunity 32 (3), 317-328, 2010
Activation of SAPK/JNK by TNF receptor 1 through a noncytotoxic TRAF2-dependent pathway
G Natoli, A Costanzo, A Ianni, DJ Templeton, JR Woodgett, C Balsano, ...
Science 275 (5297), 200-203, 1997
Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor κB
C Porta, M Rimoldi, G Raes, L Brys, P Ghezzi, D Di Liberto, F Dieli, ...
Proceedings of the National Academy of Sciences 106 (35), 14978-14983, 2009
Latent enhancers activated by stimulation in differentiated cells
R Ostuni, V Piccolo, I Barozzi, S Polletti, A Termanini, S Bonifacio, ...
Cell 152 (1-2), 157-171, 2013
Two waves of nuclear factor κB recruitment to target promoters
S Saccani, S Pantano, G Natoli
Journal of Experimental Medicine 193 (12), 1351-1360, 2001
Inhibition of NF-κB activation by arsenite through reaction with a critical cysteine in the activation loop of IκB kinase
P Kapahi, T Takahashi, G Natoli, SR Adams, Y Chen, RY Tsien, M Karin
Journal of Biological Chemistry 275 (46), 36062-36066, 2000
Memory and flexibility of cytokine gene expression as separable properties of human TH1 and TH2 lymphocytes
M Messi, I Giacchetto, K Nagata, A Lanzavecchia, G Natoli, F Sallusto
Nature immunology 4 (1), 78, 2003
Modulation of NF-κB activity by exchange of dimers
S Saccani, S Pantano, G Natoli
Molecular cell 11 (6), 1563-1574, 2003
Jmjd3 contributes to the control of gene expression in LPS‐activated macrophages
F De Santa, V Narang, ZH Yap, BK Tusi, T Burgold, L Austenaa, G Bucci, ...
The EMBO journal 28 (21), 3341-3352, 2009
Transcript dynamics of proinflammatory genes revealed by sequence analysis of subcellular RNA fractions
DM Bhatt, A Pandya-Jones, AJ Tong, I Barozzi, MM Lissner, G Natoli, ...
Cell 150 (2), 279-290, 2012
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