Jelena Mann
Jelena Mann
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Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence
G Hewitt, D Jurk, FDM Marques, C Correia-Melo, T Hardy, A Gackowska, ...
Nature communications 3 (1), 708, 2012
Chronic inflammation induces telomere dysfunction and accelerates ageing in mice
D Jurk, C Wilson, JF Passos, F Oakley, C Correia-Melo, L Greaves, ...
Nature communications 5 (1), 4172, 2014
MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis
J Mann, DCK Chu, A Maxwell, F Oakley, NL Zhu, H Tsukamoto, DA Mann
Gastroenterology 138 (2), 705-714. e4, 2010
Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence
R Anderson, A Lagnado, D Maggiorani, A Walaszczyk, E Dookun, ...
The EMBO journal 38 (5), e100492, 2019
Progress toward standardized diagnosis of vascular cognitive impairment: guidelines from the vascular impairment of cognition classification consensus study
OA Skrobot, SE Black, C Chen, C DeCarli, T Erkinjuntti, GA Ford, ...
Alzheimer's & Dementia 14 (3), 280-292, 2018
Multigenerational epigenetic adaptation of the hepatic wound-healing response
M Zeybel, T Hardy, YK Wong, JC Mathers, CR Fox, A Gackowska, ...
Nature medicine 18 (9), 1369-1377, 2012
Regulation of myofibroblast transdifferentiation by DNA methylation and MeCP2: implications for wound healing and fibrogenesis
J Mann, F Oakley, F Akiboye, A Elsharkawy, AW Thorne, DA Mann
Cell Death & Differentiation 14 (2), 275-285, 2007
Stimulating healthy tissue regeneration by targeting the 5-HT2B receptor in chronic liver disease
MR Ebrahimkhani, F Oakley, LB Murphy, J Mann, A Moles, MJ Perugorria, ...
Nature medicine 17 (12), 1668-1673, 2011
Plasma DNA methylation: a potential biomarker for stratification of liver fibrosis in non-alcoholic fatty liver disease
T Hardy, M Zeybel, CP Day, C Dipper, S Masson, S McPherson, ...
Gut 66 (7), 1321-1328, 2017
The vascular impairment of cognition classification consensus study
OA Skrobot, J O'Brien, S Black, C Chen, C DeCarli, T Erkinjuntti, GA Ford, ...
Alzheimer's & Dementia 13 (6), 624-633, 2017
Acetate, the key modulator of inflammatory responses in acute alcoholic hepatitis
SFW Kendrick, G O'Boyle, J Mann, M Zeybel, J Palmer, DEJ Jones, ...
Hepatology 51 (6), 1988-1997, 2010
IL-1α released from damaged epithelial cells is sufficient and essential to trigger inflammatory responses in human lung fibroblasts
MI Suwara, NJ Green, LA Borthwick, J Mann, KD Mayer-Barber, L Barron, ...
Mucosal immunology 7 (3), 684-693, 2014
A failure of transforming growth factor-β1 negative regulation maintains sustained NF-κB activation in gut inflammation
G Monteleone, J Mann, I Monteleone, P Vavassori, R Bremner, M Fantini, ...
Journal of Biological Chemistry 279 (6), 3925-3932, 2004
The NF-κB p50: p50: HDAC-1 repressor complex orchestrates transcriptional inhibition of multiple pro-inflammatory genes
AM Elsharkawy, F Oakley, F Lin, G Packham, DA Mann, J Mann
Journal of hepatology 53 (3), 519-527, 2010
NFκB1 is a suppressor of neutrophil-driven hepatocellular carcinoma
CL Wilson, D Jurk, N Fullard, P Banks, A Page, S Luli, AM Elsharkawy, ...
Nature communications 6 (1), 6818, 2015
Low-strength T-cell activation promotes Th17 responses
HA Purvis, JN Stoop, J Mann, S Woods, AE Kozijn, S Hambleton, ...
Blood, The Journal of the American Society of Hematology 116 (23), 4829-4837, 2010
Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis
J Argemi, MU Latasa, SR Atkinson, IO Blokhin, V Massey, JP Gue, ...
Nature communications 10 (1), 3126, 2019
A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic liver injury in the mouse
A Moles, L Murphy, CL Wilson, JB Chakraborty, C Fox, EJ Park, J Mann, ...
Journal of hepatology 60 (4), 782-791, 2014
Differential DNA methylation of genes involved in fibrosis progression in non-alcoholic fatty liver disease and alcoholic liver disease
M Zeybel, T Hardy, SM Robinson, C Fox, QM Anstee, T Ness, S Masson, ...
Clinical epigenetics 7, 1-11, 2015
Transcriptional regulation of hepatic stellate cells
J Mann, DA Mann
Advanced drug delivery reviews 61 (7-8), 497-512, 2009
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