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Pamela Chan
Pamela Chan
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Year
Antibody-drug conjugates for the treatment of non–hodgkin's lymphoma: target and linker-drug selection
AG Polson, J Calemine-Fenaux, P Chan, W Chang, E Christensen, ...
Cancer research 69 (6), 2358-2364, 2009
3072009
Antibody-based targeting of FGFR3 in bladder carcinoma and t (4; 14)-positive multiple myeloma in mice
J Qing, X Du, Y Chen, P Chan, H Li, P Wu, S Marsters, S Stawicki, J Tien, ...
The Journal of clinical investigation 119 (5), 1216-1229, 2009
2952009
Antibodies against the gH/gL/UL128/UL130/UL131 complex comprise the majority of the anti-cytomegalovirus (anti-CMV) neutralizing antibody response in CMV hyperimmune globulin
AE Fouts, P Chan, JP Stephan, R Vandlen, B Feierbach
Journal of virology 86 (13), 7444-7447, 2012
2412012
A strategy for risk mitigation of antibodies with fast clearance
I H÷tzel, FP Theil, LJ Bernstein, S Prabhu, R Deng, L Quintana, J Lutman, ...
MAbs 4 (6), 753-760, 2012
2382012
Trem2 deletion reduces late-stage amyloid plaque accumulation, elevates the Aβ42: Aβ40 ratio, and exacerbates axonal dystrophy and dendritic spine loss in the PS2APP Alzheimerá…
WJ Meilandt, H Ngu, A Gogineni, G Lalehzadeh, SH Lee, K Srinivasan, ...
Journal of Neuroscience 40 (9), 1956-1974, 2020
1352020
DCDT2980S, an anti-CD22-monomethyl auristatin E antibody–drug conjugate, is a potential treatment for non-Hodgkin lymphoma
D Li, KA Poon, SF Yu, R Dere, MA Go, J Lau, B Zheng, K Elkins, ...
Molecular cancer therapeutics 12 (7), 1255-1265, 2013
1092013
High CD21 expression inhibits internalization of anti‐CD19 antibodies and cytotoxicity of an anti‐CD19‐drug conjugate
GS Ingle, P Chan, JM Elliott, WS Chang, H Koeppen, JP Stephan, ...
British journal of haematology 140 (1), 46-58, 2008
882008
Anti-CD22-MCC-DM1 and MC-MMAF conjugates: impact of assay format on pharmacokinetic parameters determination
JP Stephan, P Chan, C Lee, C Nelson, JM Elliott, C Bechtel, H Raab, ...
Bioconjugate chemistry 19 (8), 1673-1683, 2008
872008
The immunoglobulin superfamily receptome defines cancer-relevant networks associated with clinical outcome
E Verschueren, B Husain, K Yuen, Y Sun, S Paduchuri, Y Senbabaoglu, ...
Cell 182 (2), 329-344. e19, 2020
702020
A platform for extracellular interactome discovery identifies novel functional binding partners for the immune receptors B7-H3/CD276 and PVR/CD155
B Husain, SR Ramani, E Chiang, I Lehoux, S Paduchuri, TA Arena, ...
Molecular & Cellular Proteomics 18 (11), 2310-2323, 2019
632019
A neutralizing anti-gH/gL monoclonal antibody is protective in the guinea pig model of congenital CMV infection
MR Auerbach, D Yan, R Vij, JA Hongo, G Nakamura, JM Vernes, ...
PLoS pathogens 10 (4), e1004060, 2014
502014
Widespread brain distribution and activity following icv infusion of anti‐β‐secretase (BACE1) in nonhuman primates
DB Yadav, JA Maloney, KR Wildsmith, RN Fuji, WJ Meilandt, H Solanoy, ...
British journal of pharmacology 174 (22), 4173-4185, 2017
442017
Total antibody quantification for MMAE-conjugated antibody–drug conjugates: impact of assay format and reagents
KR Kozak, SP Tsai, A Fourie-O’Donohue, J dela Cruz Chuh, L Roth, ...
Bioconjugate chemistry 24 (5), 772-779, 2013
342013
Nucleic acid capture assay, a new method for direct quantitation of nucleic acids
SP Tsai, A Wong, E Mai, P Chan, G Mausisa, M Vasser, P Jhurani, ...
Nucleic Acids Research 31 (6), e25-e25, 2003
212003
Translational approaches for brain delivery of biologics via cerebrospinal fluid
SS Sadekar, M Bowen, H Cai, S Jamalian, H Rafidi, W Shatz‐Binder, ...
Clinical Pharmacology & Therapeutics 111 (4), 826-834, 2022
202022
Taming hyperactive h DN ase I: Stable inducible expression of a hyperactive salt‐and actin‐resistant variant of human deoxyribonuclease I in CHO cells
C Lam, L Santell, B Wilson, M Yim, S Louie, D Tang, D Shaw, P Chan, ...
Biotechnology Progress 33 (2), 523-533, 2017
172017
Preclinical optimization of Ly6E-targeted ADCs for increased durability and efficacy of anti-tumor response
J Dela Cruz Chuh, MA Go, Y Chen, J Guo, H Rafidi, D Mandikian, Y Sun, ...
Mabs 13 (1), 1862452, 2021
102021
High throughput screening identifies novel, cell cycle‐arresting small molecule enhancers of transient protein expression
HJ Meyer, R Turincio, S Ng, J Li, B Wilson, P Chan, M Zak, D Reilly, ...
Biotechnology Progress 33 (6), 1579-1588, 2017
92017
Systematic discovery of Neoepitope–HLA pairs for neoantigens shared among patients and tumor types
HR Gurung, AJ Heidersbach, M Darwish, PPF Chan, J Li, M Beresini, ...
Nature Biotechnology, 1-11, 2023
82023
Nonclinical pharmacokinetics, pharmacodynamics, and translational model of RO7297089, a novel anti-BCMA/CD16A bispecific tetravalent antibody for the treatment of multiple myeloma
H Cai, S Kakiuchi-Kiyota, R Hendricks, S Zhong, L Liu, AO Adedeji, ...
The AAPS Journal 24 (6), 100, 2022
82022
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Articles 1–20