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David A. Knowles
David A. Knowles
Columbia University & New York Genome Center
Verified email at columbia.edu - Homepage
Title
Cited by
Cited by
Year
Mapping cis-and trans-regulatory effects across multiple tissues in twins
E Grundberg, KS Small, ÅK Hedman, AC Nica, A Buil, S Keildson, JT Bell, ...
Nature genetics 44 (10), 1084-1089, 2012
8132012
Predicting splicing from primary sequence with deep learning
K Jaganathan, SK Panagiotopoulou, JF McRae, SF Darbandi, D Knowles, ...
Cell 176 (3), 535-548. e24, 2019
7022019
RNA splicing is a primary link between genetic variation and disease
YI Li, B Van De Geijn, A Raj, DA Knowles, AA Petti, D Golan, Y Gilad, ...
Science 352 (6285), 600-604, 2016
4722016
Opportunities and challenges for transcriptome-wide association studies
M Wainberg, N Sinnott-Armstrong, N Mancuso, AN Barbeira, DA Knowles, ...
Nature genetics 51 (4), 592-599, 2019
3732019
Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice
LA Becker, B Huang, G Bieri, R Ma, DA Knowles, P Jafar-Nejad, ...
Nature 544 (7650), 367-371, 2017
3722017
Annotation-free quantification of RNA splicing using LeafCutter
YI Li, DA Knowles, J Humphrey, AN Barbeira, SP Dickinson, HK Im, ...
Nature genetics 50 (1), 151-158, 2018
3612018
Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements
E Grundberg, E Meduri, JK Sandling, ÅK Hedman, S Keildson, A Buil, ...
The American Journal of Human Genetics 93 (5), 876-890, 2013
3452013
Batch effects and the effective design of single-cell gene expression studies
PY Tung, JD Blischak, CJ Hsiao, DA Knowles, JE Burnett, JK Pritchard, ...
Scientific reports 7 (1), 1-15, 2017
2732017
Distinct epigenomic features in end-stage failing human hearts
M Movassagh, MK Choy, DA Knowles, L Cordeddu, S Haider, T Down, ...
Circulation 124 (22), 2411-2422, 2011
2482011
Gene expression changes with age in skin, adipose tissue, blood and brain
D Glass, A Viñuela, MN Davies, A Ramasamy, L Parts, D Knowles, ...
Genome biology 14 (7), 1-12, 2013
2432013
Infer.NET 2.4
T Minka, J Winn, J Guiver, D Knowles
Microsoft Research Cambridge http://research.microsoft.com/infernet, 2010
222*2010
Fixed-form variational posterior approximation through stochastic linear regression
T Salimans, DA Knowles
Bayesian Analysis 8 (4), 837-882, 2013
2172013
Infer.NET 2.5
T Minka, J Winn, J Guiver, D Knowles
Microsoft Research Cambridge http://research.microsoft.com/infernet, 2012
188*2012
Gaussian Process Regression Networks
AG Wilson, DA Knowles, Z Ghahramani
Proceedings of the 29th International Conference on Machine Learning (ICML 2011), 2011
1572011
Infinite sparse factor analysis and infinite independent components analysis
D Knowles, Z Ghahramani
International Conference on Independent Component Analysis and Signal …, 2007
1552007
Nonparametric Bayesian sparse factor models with application to gene expression modeling
D Knowles, Z Ghahramani
The Annals of Applied Statistics 5 (2B), 1534-1552, 2011
1492011
Landscape of stimulation-responsive chromatin across diverse human immune cells
D Calderon, MLT Nguyen, A Mezger, A Kathiria, F Müller, V Nguyen, ...
Nature genetics 51 (10), 1494-1505, 2019
1342019
Differential methylation of the TRPA1 promoter in pain sensitivity
JT Bell, AK Loomis, LM Butcher, F Gao, B Zhang, CL Hyde, J Sun, H Wu, ...
Nature communications 5 (1), 1-11, 2014
1302014
Non-conjugate Variational Message Passing for Multinomial and Binary Regression
DA Knowles, TP Minka
Advances in Neural Information Processing Systems, 2011
1302011
An infinite latent attribute model for network data
K Palla, D Knowles, Z Ghahramani
Proceedings of the 30th International Conference on Machine Learning, 2012
1222012
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Articles 1–20