| Chaste: an open source C++ library for computational physiology and biology GR Mirams, CJ Arthurs, MO Bernabeu, R Bordas, J Cooper, A Corrias, ... PLoS computational biology 9 (3), e1002970, 2013 | 500 | 2013 |
| Chaste: a test-driven approach to software development for biological modelling J Pitt-Francis, P Pathmanathan, MO Bernabeu, R Bordas, J Cooper, ... Computer Physics Communications 180 (12), 2452-2471, 2009 | 306 | 2009 |
| Comparing individual-based approaches to modelling the self-organization of multicellular tissues JM Osborne, AG Fletcher, JM Pitt-Francis, PK Maini, DJ Gavaghan PLoS computational biology 13 (2), e1005387, 2017 | 224 | 2017 |
| An integrative computational model for intestinal tissue renewal IMM Van Leeuwen, GR Mirams, A Walter, A Fletcher, P Murray, J Osborne, ... Cell proliferation 42 (5), 617-636, 2009 | 183 | 2009 |
| Cooperation, competition and antibiotic resistance in bacterial colonies I Frost, WPJ Smith, S Mitri, AS Millan, Y Davit, JM Osborne, JM Pitt-Francis, ... The ISME journal 12 (6), 1582-1593, 2018 | 175 | 2018 |
| Implementing vertex dynamics models of cell populations in biology within a consistent computational framework AG Fletcher, JM Osborne, PK Maini, DJ Gavaghan Progress in biophysics and molecular biology 113 (2), 299-326, 2013 | 175 | 2013 |
| Cell morphology drives spatial patterning in microbial communities WPJ Smith, Y Davit, JM Osborne, W Kim, KR Foster, JM Pitt-Francis Proceedings of the National Academy of Sciences 114 (3), E280-E286, 2017 | 159 | 2017 |
| A hybrid approach to multi-scale modelling of cancer JM Osborne, A Walter, SK Kershaw, GR Mirams, AG Fletcher, ... Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2010 | 153 | 2010 |
| A computational study of discrete mechanical tissue models P Pathmanathan, J Cooper, A Fletcher, G Mirams, P Murray, J Osborne, ... Physical biology 6 (3), 036001, 2009 | 147 | 2009 |
| Chaste: using agile programming techniques to develop computational biology software J Pitt-Francis, MO Bernabeu, J Cooper, A Garny, L Momtahan, J Osborne, ... Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2008 | 107 | 2008 |
| Paneth cell-rich regions separated by a cluster of Lgr5+ cells initiate crypt fission in the intestinal stem cell niche AJ Langlands, AA Almet, PL Appleton, IP Newton, JM Osborne, IS Näthke PLoS biology 14 (6), e1002491, 2016 | 106 | 2016 |
| Reversible host cell remodeling underpins deformability changes in malaria parasite sexual blood stages M Dearnley, T Chu, Y Zhang, O Looker, C Huang, N Klonis, J Yeoman, ... Proceedings of the National Academy of Sciences 113 (17), 4800-4805, 2016 | 80 | 2016 |
| Ten simple rules for a successful cross-disciplinary collaboration B Knapp, R Bardenet, MO Bernabeu, R Bordas, M Bruna, B Calderhead, ... PLoS Computational Biology 11 (4), e1004214, 2015 | 70 | 2015 |
| Chaste: cancer, heart and soft tissue environment FR Cooper, RE Baker, MO Bernabeu, R Bordas, L Bowler, ... Journal of Open Source Software 5 (47), 2020 | 65 | 2020 |
| Computational models reveal a passive mechanism for cell migration in the crypt SJ Dunn, IS Näthke, JM Osborne PloS one 8 (11), e80516, 2013 | 64 | 2013 |
| The role of the Hes1 crosstalk hub in Notch-Wnt interactions of the intestinal crypt SK Kay, HA Harrington, S Shepherd, K Brennan, T Dale, JM Osborne, ... PLoS computational biology 13 (2), e1005400, 2017 | 61 | 2017 |
| Ten simple rules for effective computational research JM Osborne, MO Bernabeu, M Bruna, B Calderhead, J Cooper, ... PLoS Computational Biology 10 (3), e1003506, 2014 | 58 | 2014 |
| A two-dimensional model of the colonic crypt accounting for the role of the basement membrane and pericryptal fibroblast sheath SJ Dunn, PL Appleton, SA Nelson, IS Näthke, DJ Gavaghan, JM Osborne PLoS computational biology 8 (5), e1002515, 2012 | 56 | 2012 |
| A modular framework for multiscale, multicellular, spatiotemporal modeling of acute primary viral infection and immune response in epithelial tissues and its application to … TJ Sego, JO Aponte-Serrano, J Ferrari Gianlupi, SR Heaps, K Breithaupt, ... PLoS computational biology 16 (12), e1008451, 2020 | 54 | 2020 |
| Hydrodynamic dispersion within porous biofilms Y Davit, H Byrne, J Osborne, J Pitt-Francis, D Gavaghan, M Quintard Physical Review E—Statistical, Nonlinear, and Soft Matter Physics 87 (1 …, 2013 | 51 | 2013 |
David GavaghanProfessor of Computational Biology, University of OxfordVerified email at cs.ox.ac.uk
