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Paul Kostenuik
Paul Kostenuik
Phylon Pharma Services, University of Michigan
Verified email at PhylonPS.com
Title
Cited by
Cited by
Year
RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism
J Li, I Sarosi, XQ Yan, S Morony, C Capparelli, HL Tan, S McCabe, ...
Proceedings of the national academy of sciences 97 (4), 1566-1571, 2000
14102000
Receptor activator of nuclear factor κB ligand and osteoprotegerin regulation of bone remodeling in health and disease
AE Kearns, S Khosla, PJ Kostenuik
Endocrine reviews 29 (2), 155-192, 2008
11102008
Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength
X Li, MS Ominsky, QT Niu, N Sun, B Daugherty, D D'Agostin, C Kurahara, ...
Journal of Bone and Mineral Research 23 (6), 860-869, 2008
11062008
Sclerostin antibody treatment increases bone formation, bone mass, and bone strength in a rat model of postmenopausal osteoporosis
X Li, MS Ominsky, KS Warmington, S Morony, J Gong, J Cao, Y Gao, ...
Journal of Bone and Mineral Research 24 (4), 578-588, 2009
9552009
Osteoprotegerin reverses osteoporosis by inhibiting endosteal osteoclasts and prevents vascular calcification by blocking a process resembling osteoclastogenesis
H Min, S Morony, I Sarosi, CR Dunstan, C Capparelli, S Scully, G Van, ...
The Journal of experimental medicine 192 (4), 463-474, 2000
7942000
Bench to bedside: elucidation of the OPG–RANK–RANKL pathway and the development of denosumab
DL Lacey, WJ Boyle, WS Simonet, PJ Kostenuik, WC Dougall, JK Sullivan, ...
Nature reviews Drug discovery 11 (5), 401-419, 2012
7402012
Growth factor regulation of fracture repair
GL Barnes, PJ Kostenuik, LC Gerstenfeld, TA Einhorn
Journal of bone and mineral research 14 (11), 1805-1815, 1999
7201999
Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia
J Li, I Sarosi, RC Cattley, J Pretorius, F Asuncion, M Grisanti, S Morony, ...
Bone 39 (4), 754-766, 2006
5442006
Denosumab, a fully human monoclonal antibody to RANKL, inhibits bone resorption and increases BMD in knock‐in mice that express chimeric (murine/human) RANKL
PJ Kostenuik, HQ Nguyen, J McCabe, KS Warmington, C Kurahara, ...
Journal of Bone and Mineral Research 24 (2), 182-195, 2009
5022009
Osteoprotegerin and RANKL regulate bone resorption, density, geometry and strength
PJ Kostenuik
Current opinion in pharmacology 5 (6), 618-625, 2005
4362005
Osteoprotegerin A Physiological and Pharmacological Inhibitor of Bone Resorption.
PJ Kostenuik
Current pharmaceutical design 7 (8), 613-635, 2001
3682001
Osteoprotegerin inhibits osteolysis and decreases skeletal tumor burden in syngeneic and nude mouse models of experimental bone metastasis
S Morony, C Capparelli, I Sarosi, DL Lacey, CR Dunstan, PJ Kostenuik
Cancer research 61 (11), 4432-4436, 2001
3592001
Osteoprotegerin Inhibits Vascular Calcification Without Affecting Atherosclerosis in ldlr(−/−) Mice
S Morony, Y Tintut, Z Zhang, RC Cattley, G Van, D Dwyer, M Stolina, ...
Circulation 117 (3), 411-420, 2008
3492008
Inhibition of sclerostin by monoclonal antibody increases bone formation, bone mass, and bone strength in aged male rats
X Li, KS Warmington, QT Niu, FJ Asuncion, M Barrero, M Grisanti, ...
Journal of Bone and Mineral Research 25 (12), 2647-2656, 2010
2852010
Comparison of effects of the bisphosphonate alendronate versus the RANKL inhibitor denosumab on murine fracture healing
LC Gerstenfeld, DJ Sacks, M Pelis, ZD Mason, DT Graves, M Barrero, ...
Journal of bone and mineral research 24 (2), 196-208, 2009
2752009
Effects of parathyroid hormone treatment on circulating sclerostin levels in postmenopausal women
MT Drake, B Srinivasan, UI Mödder, JM Peterson, LK McCready, ...
The Journal of Clinical Endocrinology & Metabolism 95 (11), 5056-5062, 2010
2632010
Effects of spaceflight on murine skeletal muscle gene expression
DL Allen, ER Bandstra, BC Harrison, S Thorng, LS Stodieck, PJ Kostenuik, ...
Journal of Applied Physiology 106 (2), 582-595, 2009
2572009
Inhibition of RANKL blocks skeletal tumor progression and improves survival in a mouse model of breast cancer bone metastasis
JR Canon, M Roudier, R Bryant, S Morony, M Stolina, PJ Kostenuik, ...
Clinical & experimental metastasis 25, 119-129, 2008
2442008
RANKL inhibition through osteoprotegerin blocks bone loss in experimental periodontitis
Q Jin, JA Cirelli, CH Park, JV Sugai, M Taba Jr, PJ Kostenuik, ...
Journal of periodontology 78 (7), 1300-1308, 2007
2442007
Estrogen regulates bone turnover by targeting RANKL expression in bone lining cells
C Streicher, A Heyny, O Andrukhova, B Haigl, S Slavic, C Schüler, ...
Scientific reports 7 (1), 1-14, 2017
2102017
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