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Melda Onal
Melda Onal
Assistant Professor
Verified email at uams.edu - Homepage
Title
Cited by
Cited by
Year
Matrix-embedded cells control osteoclast formation
J Xiong, M Onal, RL Jilka, RS Weinstein, SC Manolagas, CA O'brien
Nature medicine 17 (10), 1235-1241, 2011
14312011
Osteocytes, not osteoblasts or lining cells, are the main source of the RANKL required for osteoclast formation in remodeling bone
J Xiong, M Piemontese, M Onal, J Campbell, JJ Goellner, V Dusevich, ...
PloS one 10 (9), e0138189, 2015
3392015
Estrogen receptor-α signaling in osteoblast progenitors stimulates cortical bone accrual
M Almeida, S Iyer, M Martin-Millan, SM Bartell, L Han, E Ambrogini, ...
The Journal of clinical investigation 123 (1), 2012
2902012
Receptor activator of nuclear factor κB ligand (RANKL) protein expression by B lymphocytes contributes to ovariectomy-induced bone loss
M Onal, J Xiong, X Chen, JD Thostenson, M Almeida, SC Manolagas, ...
Journal of Biological Chemistry 287 (35), 29851-29860, 2012
2542012
Suppression of autophagy in osteocytes mimics skeletal aging
M Onal, M Piemontese, J Xiong, Y Wang, LI Han, S Ye, M Komatsu, ...
Journal of Biological Chemistry 288 (24), 17432-17440, 2013
2082013
The vitamin D receptor: contemporary genomic approaches reveal new basic and translational insights
JW Pike, MB Meyer, SM Lee, M Onal, NA Benkusky
The Journal of clinical investigation 127 (4), 1146-1154, 2017
1712017
Low bone mass and changes in the osteocyte network in mice lacking autophagy in the osteoblast lineage
M Piemontese, M Onal, J Xiong, L Han, JD Thostenson, M Almeida, ...
Scientific reports 6 (1), 24262, 2016
972016
Genomic determinants of vitamin D-regulated gene expression
JW Pike, MB Meyer, NA Benkusky, SM Lee, HS John, A Carlson, M Onal, ...
Vitamins & hormones 100, 21-44, 2016
972016
A kidney-specific genetic control module in mice governs endocrine regulation of the cytochrome P450 gene Cyp27b1 essential for vitamin D3 activation
MB Meyer, NA Benkusky, M Kaufmann, SM Lee, M Onal, G Jones, ...
Journal of Biological Chemistry 292 (42), 17541-17558, 2017
842017
A Novel Distal Enhancer Mediates Inflammation , PTH , and Early Onset Murine Kidney Disease Induced Expression of the Mouse Fgf23 Gene
M Onal, AH Carlson, JD Thostenson, NA Benkusky, MB Meyer, SM Lee, ...
Journal of Bone and Mineral Research Plus 2 (1), 31-46, 2018
592018
Suppression of autophagy in osteocytes does not modify the adverse effects of glucocorticoids on cortical bone
M Piemontese, M Onal, J Xiong, Y Wang, M Almeida, JD Thostenson, ...
Bone 75, 18-26, 2015
582015
Deletion of the Distal Tnfsf11 RL‐D2 Enhancer That Contributes to PTH‐Mediated RANKL Expression in Osteoblast Lineage Cells Results in a High Bone Mass …
M Onal, HC St. John, AL Danielson, JW Pike
Journal of Bone and Mineral Research 31 (2), 416-429, 2016
382016
Effective CRISPR interference of an endogenous gene via a single transgene in mice
RS MacLeod, KM Cawley, I Gubrij, I Nookaew, M Onal, CA O’Brien
Scientific Reports 9 (1), 17312, 2019
322019
The RANKL distal control region is required for the increase in RANKL expression, but not the bone loss, associated with hyperparathyroidism or lactation in adult mice
M Onal, C Galli, Q Fu, J Xiong, RS Weinstein, SC Manolagas, CA O'Brien
Molecular Endocrinology 26 (2), 341-348, 2012
292012
Selective regulation of Mmp13 by 1, 25 (OH) 2D3, PTH, and Osterix through distal enhancers
MB Meyer, NA Benkusky, M Onal, JW Pike
The Journal of steroid biochemistry and molecular biology 164, 258-264, 2016
282016
Unique Distal Enhancers Linked to the Mouse Tnfsf11 Gene Direct Tissue-Specific and Inflammation-Induced Expression of RANKL
M Onal, HC St. John, AL Danielson, JW Markert, EM Riley, JW Pike
Endocrinology 157 (2), 482-496, 2016
252016
A Control Region Near the Fibroblast Growth Factor 23 Gene Mediates Response to Phosphate, 1,25(OH)2D3, and LPS In Vivo
SM Lee, AH Carlson, M Onal, NA Benkusky, MB Meyer, JW Pike
Endocrinology 160 (12), 2877-2891, 2019
232019
A DNA Segment Spanning the Mouse Tnfsf11 Transcription Unit and Its Upstream Regulatory Domain Rescues the Pleiotropic Biologic Phenotype of the RANKL …
M Onal, KA Bishop, HC St. John, AL Danielson, EM Riley, M Piemontese, ...
Journal of Bone and Mineral Research 30 (5), 855-868, 2015
152015
Loss of chaperone-mediated autophagy is associated with low vertebral cancellous bone mass
N Akel, RS MacLeod, SB Berryhill, DJ Laster, M Dimori, JA Crawford, ...
Scientific Reports 12 (1), 3134, 2022
72022
Absence of the vitamin D receptor inhibits atherosclerotic plaque calcification in female hypercholesterolemic mice
S Shamsuzzaman, M Onal, HC St John, JJ Jeffery, JW Pike
Journal of Cellular Biochemistry 118 (5), 1050-1064, 2017
72017
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