| Ketamine—50 years in use: from anesthesia to rapid antidepressant effects and neurobiological mechanisms S Kohtala Pharmacological Reports 73 (2), 323-345, 2021 | 106 | 2021 |
| Isoflurane produces antidepressant effects and induces TrkB signaling in rodents H Antila, M Ryazantseva, D Popova, P Sipilä, R Guirado, S Kohtala, ... Scientific reports 7 (1), 7811, 2017 | 93 | 2017 |
| Cortical excitability and activation of TrkB signaling during rebound slow oscillations are critical for rapid antidepressant responses S Kohtala, W Theilmann, M Rosenholm, L Penna, G Karabulut, S Uusitalo, ... Molecular Neurobiology 56, 4163-4174, 2019 | 49 | 2019 |
| Brief isoflurane anesthesia produces prominent phosphoproteomic changes in the adult mouse hippocampus S Kohtala, W Theilmann, T Suomi, HK Wigren, T Porkka-Heiskanen, ... ACS chemical neuroscience 7 (6), 749-756, 2016 | 44 | 2016 |
| Encoding, consolidation, and renormalization in depression: synaptic homeostasis, plasticity, and sleep integrate rapid antidepressant effects T Rantamäki, S Kohtala Pharmacological reviews 72 (2), 439-465, 2020 | 41 | 2020 |
| Time is of the essence: coupling sleep-wake and circadian neurobiology to the antidepressant effects of ketamine S Kohtala, O Alitalo, M Rosenholm, S Rozov, T Rantamäki Pharmacology & Therapeutics 221, 107741, 2021 | 32 | 2021 |
| Brief isoflurane anesthesia regulates striatal AKT‐GSK3β signaling and ameliorates motor deficits in a rat model of early‐stage Parkinson′ s disease JV Leikas, S Kohtala, W Theilmann, AJ Jalkanen, MM Forsberg, ... Journal of neurochemistry 142 (3), 456-463, 2017 | 28 | 2017 |
| Ketamine-induced regulation of TrkB-GSK3β signaling is accompanied by slow EEG oscillations and sedation but is independent of hydroxynorketamine metabolites S Kohtala, W Theilmann, M Rosenholm, HK Müller, P Kiuru, G Wegener, ... Neuropharmacology 157, 107684, 2019 | 25 | 2019 |
| A wake-up call: Sleep physiology and related translational discrepancies in studies of rapid-acting antidepressants O Alitalo, R Saarreharju, ID Henter, CA Zarate Jr, S Kohtala, T Rantamäki Progress in neurobiology 206, 102140, 2021 | 11* | 2021 |
| Ketamine reduces electrophysiological network activity in cortical neuron cultures already at sub-micromolar concentrations–Impact on TrkB-ERK1/2 signaling A Ahtiainen, I Annala, M Rosenholm, S Kohtala, J Hyttinen, ... Neuropharmacology 229, 109481, 2023 | 8 | 2023 |
| Rapid‐acting antidepressants and the regulation of TrkB neurotrophic signalling—insights from ketamine, nitrous oxide, seizures and anaesthesia S Kohtala, T Rantamäki Basic & Clinical Pharmacology & Toxicology 129 (2), 95-103, 2021 | 8 | 2021 |
| Dyskinesia and brain-derived neurotrophic factor levels after long-term levodopa and nicotinic receptor agonist treatments in female mice with near-total unilateral … S Leino, S Kohtala, T Rantamäki, SK Koski, S Rannanpää, O Salminen BMC neuroscience 19, 1-10, 2018 | 7 | 2018 |
| Linking Hypothermia and Altered Metabolism with TrkB Activation O Alitalo, G González-Hernández, M Rosenholm, P Kohtala, N Matsui, ... ACS chemical neuroscience 14 (17), 3212-3225, 2023 | 4* | 2023 |
| Commentary: commonly used anesthesia/euthanasia methods for brain collection differentially impact MAPK activity in male and female C57BL/6 mice S Kohtala, T Rantamäki Frontiers in Cellular Neuroscience 13, 219, 2019 | 3 | 2019 |
| Rapid-acting antidepressants: Shared neuropharmacological mechanisms S Kohtala Helsingin yliopisto, 2019 | 2 | 2019 |
| Neurobiologiset ilmiöt nopean masennuslääkevasteen taustalla S Kohtala, K Järventausta, T Rantamäki | 2 | 2018 |
| Nitrous oxide induces hypothermia and TrkB activation: Maintenance of body temperature abolishes antidepressant-like effects in mice O Alitalo, S Kohtala, M Rosenholm, R Saarreharju, ... Neuropharmacology 261, 110172, 2024 | | 2024 |
Tomi RantamäkiProfessorVerified email at helsinki.fi
