The identification of markers of macrophage differentiation in PMA-stimulated THP-1 cells and monocyte-derived macrophages M Daigneault, JA Preston, HM Marriott, MKB Whyte, DH Dockrell PloS one 5 (1), e8668, 2010 | 1394 | 2010 |
Alveolar macrophage apoptosis contributes to pneumococcal clearance in a resolving model of pulmonary infection DH Dockrell, HM Marriott, LR Prince, VC Ridger, PG Ince, PG Hellewell, ... The Journal of Immunology 171 (10), 5380-5388, 2003 | 306 | 2003 |
Pneumolysin: a double-edged sword during the host-pathogen interaction HM Marriott, TJ Mitchell, DH Dockrell Current molecular medicine 8 (6), 497-509, 2008 | 242 | 2008 |
Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice SR Walmsley, ER Chilvers, AA Thompson, K Vaughan, HM Marriott, ... The Journal of clinical investigation 121 (3), 1053-1063, 2011 | 212 | 2011 |
Alveolar macrophages in pulmonary host defence–the unrecognized role of apoptosis as a mechanism of intracellular bacterial killing JD Aberdein, J Cole, MA Bewley, HM Marriott, DH Dockrell Clinical & Experimental Immunology 174 (2), 193-202, 2013 | 178 | 2013 |
TNF-related apoptosis-inducing ligand (TRAIL) regulates inflammatory neutrophil apoptosis and enhances resolution of inflammation EE McGrath, HM Marriott, A Lawrie, SE Francis, I Sabroe, SA Renshaw, ... Journal of leukocyte biology 90 (5), 855-865, 2011 | 163 | 2011 |
Nitric oxide levels regulate macrophage commitment to apoptosis or necrosis during pneumococcal infection HM Marriott, F Ali, RC Read, TJ Mitchell, MKB Whyte, DH Dockrell The FASEB journal 18 (10), 1126-1128, 2004 | 163 | 2004 |
Hypoxia-inducible factor 2α regulates key neutrophil functions in humans, mice, and zebrafish AAR Thompson, PM Elks, HM Marriott, S Eamsamarng, KR Higgins, ... Blood, The Journal of the American Society of Hematology 123 (3), 366-376, 2014 | 162 | 2014 |
Inhibition of neutrophil apoptosis by ATP is mediated by the P2Y11 receptor KR Vaughan, L Stokes, LR Prince, HM Marriott, S Meis, MU Kassack, ... The Journal of Immunology 179 (12), 8544-8553, 2007 | 145 | 2007 |
Impairment of apoptotic cell engulfment by pyocyanin, a toxic metabolite of Pseudomonas aeruginosa SM Bianchi, LR Prince, K McPhillips, L Allen, HM Marriott, GW Taylor, ... American journal of respiratory and critical care medicine 177 (1), 35-43, 2008 | 136 | 2008 |
Dynamic changes in Mcl-1 expression regulate macrophage viability or commitment to apoptosis during bacterial clearance HM Marriott, CD Bingle, RC Read, KE Braley, G Kroemer, PG Hellewell, ... The Journal of clinical investigation 115 (2), 359-368, 2005 | 134 | 2005 |
Inability to sustain intraphagolysosomal killing of Staphylococcus aureus predisposes to bacterial persistence in macrophages J Jubrail, P Morris, MA Bewley, S Stoneham, SA Johnston, SJ Foster, ... Cellular microbiology 18 (1), 80-96, 2016 | 129 | 2016 |
Distinct cell death programs in monocytes regulate innate responses following challenge with common causes of invasive bacterial disease SJ Webster, M Daigneault, MA Bewley, JA Preston, H Marriott, ... The Journal of Immunology 185 (5), 2968-2979, 2010 | 129 | 2010 |
Decreased alveolar macrophage apoptosis is associated with increased pulmonary inflammation in a murine model of pneumococcal pneumonia HM Marriott, PG Hellewell, SS Cross, PG Ince, MKB Whyte, DH Dockrell The Journal of Immunology 177 (9), 6480-6488, 2006 | 127 | 2006 |
The role of the macrophage in lung disease mediated by bacteria HM Marriott, DH Dockrell Experimental lung research 33 (10), 493-505, 2007 | 121 | 2007 |
Interleukin-1β regulates CXCL8 release and influences disease outcome in response to Streptococcus pneumoniae, defining intercellular cooperation between pulmonary epithelial … HM Marriott, KA Gascoyne, R Gowda, I Geary, MJH Nicklin, F Iannelli, ... Infection and immunity 80 (3), 1140-1149, 2012 | 117 | 2012 |
A cardinal role for cathepsin d in co-ordinating the host-mediated apoptosis of macrophages and killing of pneumococci MA Bewley, HM Marriott, C Tulone, SE Francis, TJ Mitchell, RC Read, ... PLoS pathogens 7 (1), e1001262, 2011 | 104 | 2011 |
Reactive oxygen species regulate neutrophil recruitment and survival in pneumococcal pneumonia HM Marriott, LE Jackson, TS Wilkinson, AJ Simpson, TJ Mitchell, DJ Buttle, ... American journal of respiratory and critical care medicine 177 (8), 887-895, 2008 | 104 | 2008 |
Impaired mitochondrial microbicidal responses in chronic obstructive pulmonary disease macrophages MA Bewley, JA Preston, M Mohasin, HM Marriott, RC Budd, J Swales, ... American journal of respiratory and critical care medicine 196 (7), 845-855, 2017 | 101 | 2017 |
Subversion of a lysosomal pathway regulating neutrophil apoptosis by a major bacterial toxin, pyocyanin LR Prince, SM Bianchi, KM Vaughan, MA Bewley, HM Marriott, ... The Journal of Immunology 180 (5), 3502-3511, 2008 | 95 | 2008 |