| The structure of holo and metal-deficient wild-type human Cu, Zn superoxide dismutase and its relevance to familial amyotrophic lateral sclerosis RW Strange, S Antonyuk, MA Hough, PA Doucette, JA Rodriguez, PJ Hart, ... Journal of molecular biology 328 (4), 877-891, 2003 | 305 | 2003 |
| Dimer destabilization in superoxide dismutase may result in disease-causing properties: structures of motor neuron disease mutants MA Hough, JG Grossmann, SV Antonyuk, RW Strange, PA Doucette, ... Proceedings of the National Academy of Sciences 101 (16), 5976-5981, 2004 | 275 | 2004 |
| Variable metallation of human superoxide dismutase: atomic resolution crystal structures of Cu–Zn, Zn–Zn and as-isolated wild-type enzymes RW Strange, SV Antonyuk, MA Hough, PA Doucette, JS Valentine, ... Journal of molecular biology 356 (5), 1152-1162, 2006 | 192 | 2006 |
| Crystallographic structures of bovine copper-zinc superoxide dismutase reveal asymmetry in two subunits: functionally important three and five coordinate copper sites captured … MA Hough, SS Hasnain Journal of molecular biology 287 (3), 579-592, 1999 | 132 | 1999 |
| The CCP4 suite: integrative software for macromolecular crystallography J Agirre, M Atanasova, H Bagdonas, CB Ballard, A Baslé, ... Acta Crystallographica Section D: Structural Biology 79 (6), 449-461, 2023 | 123 | 2023 |
| Structure of fully reduced bovine copper zinc superoxide dismutase at 1.15 Å MA Hough, SS Hasnain Structure 11 (8), 937-946, 2003 | 99 | 2003 |
| The hydrogen-peroxide-induced radical behaviour in human cytochrome c–phospholipid complexes: implications for the enhanced pro-apoptotic activity of the … BS Rajagopal, AN Edzuma, MA Hough, KLIM Blundell, VE Kagan, ... Biochemical Journal 456 (3), 441-452, 2013 | 95 | 2013 |
| Crystallography with online optical and X-ray absorption spectroscopies demonstrates an ordered mechanism in copper nitrite reductase MA Hough, SV Antonyuk, RW Strange, RR Eady, SS Hasnain Journal of molecular biology 378 (2), 353-361, 2008 | 93 | 2008 |
| Structural consequences of the familial amyotrophic lateral sclerosis SOD1 mutant His46Arg S Antonyuk, JS Elam, MA Hough, RW Strange, PA Doucette, ... Protein Science 14 (5), 1201-1213, 2005 | 90 | 2005 |
| GlxA is a new structural member of the radical copper oxidase family and is required for glycan deposition at hyphal tips and morphogenesis of Streptomyces lividans AK Chaplin, MLC Petrus, G Mangiameli, MA Hough, DA Svistunenko, ... Biochemical Journal 469 (3), 433-444, 2015 | 73 | 2015 |
| Proton-Coupled Electron Transfer in the Catalytic Cycle of Alcaligenes xylosoxidans Copper-Dependent Nitrite Reductase NGH Leferink, C Han, SV Antonyuk, DJ Heyes, SEJ Rigby, MA Hough, ... Biochemistry 50 (19), 4121-4131, 2011 | 73 | 2011 |
| Response to copper stress in Streptomyces lividans extends beyond genes under direct control of a copper-sensitive operon repressor protein (CsoR) S Dwarakanath, AK Chaplin, MA Hough, S Rigali, E Vijgenboom, ... Journal of Biological Chemistry 287 (21), 17833-17847, 2012 | 70 | 2012 |
| Dose-resolved serial synchrotron and XFEL structures of radiation-sensitive metalloproteins A Ebrahim, T Moreno-Chicano, MV Appleby, AK Chaplin, JH Beale, ... IUCrJ 6 (4), 543-551, 2019 | 69 | 2019 |
| Heterogeneity in the histidine-brace copper coordination sphere in auxiliary activity family 10 (AA10) lytic polysaccharide monooxygenases AK Chaplin, MT Wilson, MA Hough, DA Svistunenko, GR Hemsworth, ... Journal of Biological Chemistry 291 (24), 12838-12850, 2016 | 69 | 2016 |
| Serial crystallography captures enzyme catalysis in copper nitrite reductase at atomic resolution from one crystal S Horrell, SV Antonyuk, RR Eady, SS Hasnain, MA Hough, RW Strange IUCrJ 3 (4), 271-281, 2016 | 62 | 2016 |
| Conformational variability of the Cu site in one subunit of bovine CuZn superoxide dismutase: the importance of mobility in the Glu119-Leu142 loop region for catalytic function MA Hough, RW Strange, SS Hasnain Journal of Molecular Biology 304 (2), 231-241, 2000 | 62 | 2000 |
| Recent structural insights into the function of copper nitrite reductases S Horrell, D Kekilli, RW Strange, MA Hough Metallomics 9 (11), 1470-1482, 2017 | 60 | 2017 |
| Demonstration of proton-coupled electron transfer in the copper-containing nitrite reductases S Brenner, DJ Heyes, S Hay, MA Hough, RR Eady, SS Hasnain, ... Journal of biological chemistry 284 (38), 25973-25983, 2009 | 57 | 2009 |
| Crystal structures of the Met148Leu and Ser86Asp mutants of rusticyanin from Thiobacillus ferrooxidans: insights into the structural relationship with the cupredoxins and the … LD Kanbi, S Antonyuk, MA Hough, JF Hall, FE Dodd, SS Hasnain Journal of molecular biology 320 (2), 263-275, 2002 | 54 | 2002 |
| Atomic Resolution Crystal Structures, EXAFS, and Quantum Chemical Studies of Rusticyanin and Its Two Mutants Provide Insight into Its Unusual Properties, ML Barrett, I Harvey, M Sundararajan, R Surendran, JF Hall, MJ Ellis, ... Biochemistry 45 (9), 2927-2939, 2006 | 52 | 2006 |
S S HasnainMax Perutz Professor of Molecular Biophysics, University of LiverpoolVerified email at liverpool.ac.uk
