| Regulation of autophagy by ATF4 in response to severe hypoxia T Rzymski, M Milani, L Pike, F Buffa, HR Mellor, L Winchester, I Pires, ... Oncogene 29 (31), 4424-4435, 2010 | 423 | 2010 |
| Anticancer properties of essential oils and other natural products K Blowman, M Magalhães, MFL Lemos, C Cabral, IM Pires Evidence-based complementary and alternative medicine 2018, 2018 | 261 | 2018 |
| Contextual synthetic lethality of cancer cell kill based on the tumor microenvironment N Chan, IM Pires, Z Bencokova, C Coackley, KR Luoto, N Bhogal, ... Cancer research 70 (20), 8045-8054, 2010 | 260 | 2010 |
| ATM activation and signaling under hypoxic conditions Z Bencokova, MR Kaufmann, IM Pires, PS Lecane, AJ Giaccia, ... Molecular and cellular biology, 2009 | 255 | 2009 |
| Effects of acute versus chronic hypoxia on DNA damage responses and genomic instability IM Pires, Z Bencokova, M Milani, LK Folkes, JL Li, MR Stratford, AL Harris, ... Cancer research 70 (3), 925-935, 2010 | 219 | 2010 |
| Targeting radiation-resistant hypoxic tumour cells through ATR inhibition IM Pires, MM Olcina, S Anbalagan, JR Pollard, PM Reaper, PA Charlton, ... British journal of cancer 107 (2), 291-299, 2012 | 213 | 2012 |
| Replication stress and chromatin context link ATM activation to a role in DNA replication MM Olcina, IP Foskolou, S Anbalagan, JM Senra, IM Pires, Y Jiang, ... Molecular cell 52 (5), 758-766, 2013 | 122 | 2013 |
| RASSF1A–LATS1 signalling stabilizes replication forks by restricting CDK2-mediated phosphorylation of BRCA2 DE Pefani, R Latusek, I Pires, AM Grawenda, KS Yee, G Hamilton, ... Nature Cell Biology 16 (10), 962-971, 2014 | 98 | 2014 |
| CH-01 is a hypoxia-activated prodrug that sensitizes cells to hypoxia/reoxygenation through inhibition of Chk1 and Aurora A C Cazares-Körner, IM Pires, ID Swallow, SC Grayer, LJ O’Connor, ... ACS chemical biology 8 (7), 1451-1459, 2013 | 66 | 2013 |
| Radiosensitization of renal cell carcinoma in vitro through the induction of autophagy S Anbalagan, IM Pires, C Blick, MA Hill, DJP Ferguson, DA Chan, ... Radiotherapy and Oncology 103 (3), 388-393, 2012 | 55 | 2012 |
| Use of the xCELLigence system for real-time analysis of changes in cellular motility and adhesion in physiological conditions S Scrace, E O’Neill, EM Hammond, IM Pires Adhesion Protein Protocols, 295-306, 2013 | 50 | 2013 |
| Oxaliplatin responses in colorectal cancer cells are modulated by CHK2 kinase inhibitors IM Pires, TH Ward, C Dive British journal of pharmacology 159 (6), 1326-1338, 2010 | 43 | 2010 |
| Hypoxia-driven cell motility reflects the interplay between JMY and HIF-1α AS Coutts, IM Pires, L Weston, FM Buffa, M Milani, JL Li, AL Harris, ... Oncogene 30 (48), 4835-4842, 2011 | 42 | 2011 |
| Secondary metabolites (essential oils) from sand-dune plants induce cytotoxic effects in cancer cells E Beeby, M Magalhães, J Poças, T Collins, MFL Lemos, L Barros, ... Journal of ethnopharmacology 258, 112803, 2020 | 39 | 2020 |
| Fission yeast Dss1 associates with the proteasome and is required for efficient ubiquitin-dependent proteolysis L Jossé, ME Harley, IMS Pires, DA Hughes Biochemical Journal 393 (1), 303-309, 2006 | 38 | 2006 |
| Evaluation of the first potent and highly selective inhibitor of ATR kinase: an approach to selectively sensitize cancer cells to ionizing radiation and hypoxia G McKenna, T Brunner, P Charlton, E Fokas, E Hammond, M Mangan, ... Cancer Research 71 (8_Supplement), 5501-5501, 2011 | 34 | 2011 |
| Exposure to acute hypoxia induces a transient DNA damage response which includes Chk1 and TLK1 IM Pires, Z Bencokova, C McGurk, EM Hammond Cell cycle 9 (13), 2502-2507, 2010 | 32 | 2010 |
| The role of glucosinolates from cruciferous vegetables (Brassicaceae) in gastrointestinal cancers: from prevention to therapeutics C Melim, MR Lauro, IM Pires, PJ Oliveira, C Cabral Pharmaceutics 14 (1), 190, 2022 | 29 | 2022 |
| HIF-1α-independent hypoxia-induced rapid PTK6 stabilization is associated with increased motility and invasion IM Pires, NJG Blokland, AWT Broos, FA Poujade, JM Senra, SA Eccles, ... Cancer biology & therapy 15 (10), 1350-1357, 2014 | 28 | 2014 |
| Spheroid-on-chip microfluidic technology for the evaluation of the impact of continuous flow on metastatic potential in cancer models in vitro T Collins, E Pyne, M Christensen, A Iles, N Pamme, IM Pires Biomicrofluidics 15 (4), 2021 | 21 | 2021 |
Ester HammondDepartment of Oncology, University of OxfordVerified email at oncology.ox.ac.uk
