The type I TGF-β receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner A Sorrentino, N Thakur, S Grimsby, A Marcusson, V Von Bulow, ... Nature cell biology 10 (10), 1199-1207, 2008 | 659 | 2008 |
TRAF6 ubiquitinates TGFβ type I receptor to promote its cleavage and nuclear translocation in cancer Y Mu, R Sundar, N Thakur, M Ekman, SK Gudey, M Yakymovych, ... Nature communications 2 (1), 330, 2011 | 208 | 2011 |
TGF-β promotes PI3K-AKT signaling and prostate cancer cell migration through the TRAF6-mediated ubiquitylation of p85α A Hamidi, J Song, N Thakur, S Itoh, A Marcusson, A Bergh, CH Heldin, ... Science signaling 10 (486), eaal4186, 2017 | 203 | 2017 |
An Antisense RNA Regulates the Bidirectional Silencing Property of the Kcnq1 Imprinting Control Region N Thakur, VK Tiwari, H Thomassin, RR Pandey, M Kanduri, A Göndör, ... Molecular and cellular biology 24 (18), 7855-7862, 2004 | 197 | 2004 |
The length of the transcript encoded from the Kcnq1ot1 antisense promoter determines the degree of silencing C Kanduri, N Thakur, RR Pandey The EMBO journal 25 (10), 2096-2106, 2006 | 94 | 2006 |
TGFβ1-induced activation of ATM and p53 mediates apoptosis in a Smad7-dependent manner S Zhang, M Ekman, N Thakur, S Bu, P Davoodpour, S Grimsby, S Tagami, ... Cell cycle 5 (23), 2787-2795, 2006 | 74 | 2006 |
TGFβ-induced invasion of prostate cancer cells is promoted by c-Jun-dependent transcriptional activation of Snail1 N Thakur, SK Gudey, A Marcusson, JY Fu, A Bergh, CH Heldin, ... Cell Cycle 13 (15), 2400-2414, 2014 | 73 | 2014 |
Bidirectional silencing and DNA methylation-sensitive methylation-spreading properties of the Kcnq1 imprinting control region map to the same regions N Thakur, M Kanduri, C Holmgren, R Mukhopadhyay, C Kanduri Journal of Biological Chemistry 278 (11), 9514-9519, 2003 | 51 | 2003 |
APC and Smad7 link TGFβ type I receptors to the microtubule system to promote cell migration M Ekman, Y Mu, SY Lee, S Edlund, T Kozakai, N Thakur, H Tran, J Qian, ... Molecular biology of the cell 23 (11), 2109-2121, 2012 | 40 | 2012 |
TGF-β uses the E3-ligase TRAF6 to turn on the kinase TAK1 to kill prostate cancer cells N Thakur, A Sorrentino, CH Heldin, M Landström Future Medicine 5 (1), 1-3, 2009 | 32 | 2009 |
Smad7 enhances TGF-β-induced transcription of c-Jun and HDAC6 promoting invasion of prostate cancer cells N Thakur, A Hamidi, J Song, S Itoh, A Bergh, CH Heldin, M Landström Iscience 23 (9), 2020 | 20 | 2020 |
The kinetics of deregulation of expression by de novo methylation of the h19 imprinting control region in cancer cells C Kanduri, M Kanduri, L Liu, N Thakur, S Pfeifer, R Ohlsson Cancer research 62 (16), 4545-4548, 2002 | 19 | 2002 |
GSK‐J4: An H3K27 histone demethylase inhibitor, as a potential anti‐cancer agent N Dalpatraj, A Naik, N Thakur International Journal of Cancer 153 (6), 1130-1138, 2023 | 9 | 2023 |
Combination Treatment of a Phytochemical and a Histone Demethylase Inhibitor—A Novel Approach towards Targeting TGFβ-Induced EMT, Invasion, and Migration in Prostate Cancer N Dalpatraj, A Naik, N Thakur International Journal of Molecular Sciences 24 (3), 1860, 2023 | 5 | 2023 |
Global Histone H3 lysine 4 trimethylation (H3K4me3) landscape changes in response to TGFβ A Naik, N Dalpatraj, N Thakur Epigenetics Insights 14, 25168657211051755, 2021 | 4 | 2021 |
Hesperetin modulates TGFβ induced metastatic potential of prostate cancer cells by altering histone methylation marks N Dalpatraj, J Tak, A Naik, N Thakur Advances in Cancer Biology-Metastasis 6, 100077, 2022 | 3 | 2022 |
Global Gene Expression Regulation Mediated by TGFβ Through H3K9me3 Mark A Naik, N Dalpatraj, N Thakur Cancer Informatics 21, 11769351221115135, 2022 | 2 | 2022 |
TGFβ promotes cancer cell migration via TRAF6-specific ubiquitination of p85α causing activation of the PI3K/AKT pathway A Hamidi, N Thakur, A Marcusson, CH Heldin, M Landstöm Science Signaling, 2015 | 2 | 2015 |
Long-range Control of Gene Expression by Imprinting Control Regions During Development and Neoplasia N Thakur Acta Universitatis Upsaliensis, 2005 | 1 | 2005 |
Comparative analysis of the occupancy of Histone H3 Lysine 4 methylation in the cells treated with TGFβ and Interferonγ A Naik, N Dalpatraj, N Thakur Gene 879, 147601, 2023 | | 2023 |