Professor Hai Deng
Professor Hai Deng
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Crystal structure and mechanism of a bacterial fluorinating enzyme
C Dong, F Huang, H Deng, C Schaffrath, JB Spencer, D O'hagan, ...
Nature 427 (6974), 561-565, 2004
Enzymatic Fluorination and Biotechnological Developments of the Fluorinase
D O'Hagan, H Deng
Chemical Reviews 115 (2), 634-649, 2014
Diverse metabolic profiles of a Streptomyces strain isolated from a hyper-arid environment
ME Rateb, WE Houssen, WTA Harrison, H Deng, CK Okoro, JA Asenjo, ...
Journal of natural products 74 (9), 1965-1971, 2011
Upconversion NIR-II fluorophores for mitochondria-targeted cancer imaging and photothermal therapy
H Zhou, X Zeng, A Li, W Zhou, L Tang, W Hu, Q Fan, X Meng, H Deng, ...
Nature Communications 11 (1), 6183, 2020
Chaxamycins A–D, Bioactive Ansamycins from a Hyper-arid Desert Streptomyces sp.
ME Rateb, WE Houssen, M Arnold, MH Abdelrahman, H Deng, ...
Journal of natural products 74 (6), 1491-1499, 2011
Novel NIR-II organic fluorophores for bioimaging beyond 1550 nm
Y Li, Y Liu, Q Li, X Zeng, T Tian, W Zhou, Y Cui, X Wang, X Cheng, Q Ding, ...
Chemical Science 11 (10), 2621-2626, 2020
Fluorometabolite biosynthesis and the fluorinase from Streptomyces cattleya
H Deng, D O'Hagan, C Schaffrath
Natural product reports 21 (6), 773-784, 2004
Identification of Fluorinases from Streptomyces sp MA37, Norcardia brasiliensis, and Actinoplanes sp N902‐109 by Genome Mining
H Deng, L Ma, N Bandaranayaka, Z Qin, G Mann, K Kyeremeh, Y Yu, ...
ChemBioChem 15 (3), 364-368, 2014
The fluorinase from Streptomyces cattleya is also a chlorinase
H Deng, SL Cobb, AR McEwan, RP McGlinchey, JH Naismith, D O’Hagan, ...
Angewandte Chemie (International ed. in English) 45 (5), 759, 2006
Chaxapeptin, a Lasso Peptide from Extremotolerant Streptomyces leeuwenhoekii Strain C58 from the Hyperarid Atacama Desert
SS Elsayed, F Trusch, H Deng, A Raab, I Prokes, K Busarakam, ...
The Journal of organic chemistry 80 (20), 10252-10260, 2015
Isolation and characterisation of 5′-fluorodeoxyadenosine synthase, a fluorination enzyme from Streptomyces cattleya
C Schaffrath, H Deng, D O’Hagan
FEBS letters 547 (1-3), 111-114, 2003
Enzymatic fluorination in Streptomyces cattleya takes place with an inversion of configuration consistent with an SN2 reaction mechanism
CD Cadicamo, J Courtieu, H Deng, A Meddour, D O'Hagan
ChemBioChem 5 (5), 685-690, 2004
The first enzymatic method for C–18F bond formation: the synthesis of 5′‐[18F]‐fluoro‐5′‐deoxyadenosine for imaging with PET
L Martarello, C Schaffrath, H Deng, AD Gee, A Lockhart, D O'Hagan
Journal of Labelled Compounds and Radiopharmaceuticals: The Official Journal …, 2003
Fluorinase mediated C–18 F bond formation, an enzymatic tool for PET labelling
H Deng, SL Cobb, AD Gee, A Lockhart, L Martarello, RP McGlinchey, ...
Chemical communications, 652-654, 2006
The fluorinase, the chlorinase and the duf-62 enzymes
H Deng, D O’Hagan
Current opinion in chemical biology 12 (5), 582-592, 2008
Identification of a fluorometabolite from Streptomyces sp. MA37:(2 R 3 S 4 S)-5-fluoro-2, 3, 4-trihydroxypentanoic acid
L Ma, A Bartholome, MH Tong, Z Qin, Y Yu, T Shepherd, K Kyeremeh, ...
Chemical science 6 (2), 1414-1419, 2015
Fluoroacetate biosynthesis from the marine-derived bacterium Streptomyces xinghaiensis NRRL B-24674
S Huang, L Ma, MH Tong, Y Yu, D O'Hagan, H Deng
Organic & Biomolecular Chemistry, 2014
Dithiolopyrrolone natural products: isolation, synthesis and biosynthesis
Z Qin, S Huang, Y Yu, H Deng
Marine drugs 11 (10), 3970-3997, 2013
Fluorine speciation analysis using reverse phase liquid chromatography coupled off-line to continuum source molecular absorption spectrometry (CS-MAS): identification and …
Z Qin, D McNee, H Gleisner, A Raab, K Kyeremeh, M Jaspars, E Krupp, ...
Analytical chemistry 84 (14), 6213-6219, 2012
Discovery of a single monooxygenase that catalyzes carbamate formation and ring contraction in the biosynthesis of the legonmycins
S Huang, J Tabudravu, SS Elsayed, J Travert, D Peace, MH Tong, ...
Angewandte Chemie International Edition 54 (43), 12697-12701, 2015
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