Follow
Luigi Iconaru
Luigi Iconaru
Verified email at sanofi.com
Title
Cited by
Cited by
Year
CDK2 inhibitors as candidate therapeutics for cisplatin-and noise-induced hearing loss
T Teitz, J Fang, AN Goktug, JD Bonga, S Diao, RA Hazlitt, L Iconaru, ...
Journal of Experimental Medicine 215 (4), 1187-1203, 2018
992018
Discovery of Small Molecules that Inhibit the Disordered Protein, p27Kip1
LI Iconaru, D Ban, K Bharatham, A Ramanathan, W Zhang, AA Shelat, ...
Scientific reports 5 (1), 15686, 2015
862015
Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation
M Tsytlonok, H Sanabria, Y Wang, S Felekyan, K Hemmen, AH Phillips, ...
Nature communications 10 (1), 1676, 2019
852019
Electrostatically accelerated coupled binding and folding of intrinsically disordered proteins
D Ganguly, S Otieno, B Waddell, L Iconaru, RW Kriwacki, J Chen
Journal of molecular biology 422 (5), 674-684, 2012
842012
Fused polycyclic nucleophilic carbenes–synthesis, structure, and function
AJ Arduengo Iii, LI Iconaru
Dalton Transactions, 6903-6914, 2009
702009
A small molecule causes a population shift in the conformational landscape of an intrinsically disordered protein
D Ban, LI Iconaru, A Ramanathan, J Zuo, RW Kriwacki
Journal of the American Chemical Society 139 (39), 13692-13700, 2017
452017
Real‐Time Analysis of Folding upon Binding of a Disordered Protein by Using Dissolution DNP NMR Spectroscopy
M Ragavan, LI Iconaru, CG Park, RW Kriwacki, C Hilty
Angewandte Chemie International Edition 56 (25), 7070-7073, 2017
392017
Development of second-generation CDK2 inhibitors for the prevention of cisplatin-induced hearing loss
RA Hazlitt, T Teitz, JD Bonga, J Fang, S Diao, L Iconaru, L Yang, ...
Journal of medicinal chemistry 61 (17), 7700-7709, 2018
362018
Small molecule sequestration of the intrinsically disordered protein, p27Kip1, within soluble oligomers
LI Iconaru, S Das, A Nourse, AA Shelat, J Zuo, RW Kriwacki
Journal of molecular biology 433 (18), 167120, 2021
222021
Design, synthesis and evaluation of 2, 5-diketopiperazines as inhibitors of the MDM2-p53 interaction
M Pettersson, M Quant, J Min, L Iconaru, RW Kriwacki, MB Waddell, ...
PLoS one 10 (10), e0137867, 2015
222015
High-Throughput Screening Reveals Alsterpaullone, 2-Cyanoethyl as a Potent p27Kip1 Transcriptional Inhibitor
BJ Walters, W Lin, S Diao, M Brimble, LI Iconaru, J Dearman, A Goktug, ...
PloS one 9 (3), e91173, 2014
202014
8-Triazolylpurines: Towards fluorescent inhibitors of the MDM2/p53 interaction
M Pettersson, D Bliman, J Jacobsson, JR Nilsson, J Min, L Iconaru, ...
PLoS One 10 (5), e0124423, 2015
142015
Two Decades of IDPs; What have we Learned?
R Kriwacki, DM Mitrea, A Follis, L Iconaru, J Cika, D Ban, A Philllips
Biophysical Journal 112 (3), 12a-13a, 2017
32017
Fused polycyclic imidazoles
LI Iconaru
The University of Alabama Electronic Theses and Dissertations, 2009
22009
Small molecules that bind cyclin-dependent kinase inhibitor 1b (p27kip1)
R Kriwacki, J Zuo, L Iconaru, S Das, A Shelat, B Young
US Patent App. 17/438,857, 2022
2022
A Quest for Small Molecule Inhibitors of the Cell Cycle Regulator, P27
LI Iconaru, A Shelat, J Zuo, RW Kriwacki
Biophysical Journal 102 (3), 635a, 2012
2012
Progress toward the stabilization of fused polycyclic nucleophilic carbenes
AJ Arduengo III, LI Iconaru
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 238, 64-64, 2009
2009
ORGN 389-Toward the stabilization of fused tricyclic-tris (carbenes)
AJ Arduengo III, LI Iconaru
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 235, 2008
2008
The system can't perform the operation now. Try again later.
Articles 1–18