CDK2 inhibitors as candidate therapeutics for cisplatin-and noise-induced hearing loss T Teitz, J Fang, AN Goktug, JD Bonga, S Diao, RA Hazlitt, L Iconaru, ... Journal of Experimental Medicine 215 (4), 1187-1203, 2018 | 99 | 2018 |
Discovery of Small Molecules that Inhibit the Disordered Protein, p27Kip1 LI Iconaru, D Ban, K Bharatham, A Ramanathan, W Zhang, AA Shelat, ... Scientific reports 5 (1), 15686, 2015 | 86 | 2015 |
Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation M Tsytlonok, H Sanabria, Y Wang, S Felekyan, K Hemmen, AH Phillips, ... Nature communications 10 (1), 1676, 2019 | 85 | 2019 |
Electrostatically accelerated coupled binding and folding of intrinsically disordered proteins D Ganguly, S Otieno, B Waddell, L Iconaru, RW Kriwacki, J Chen Journal of molecular biology 422 (5), 674-684, 2012 | 84 | 2012 |
Fused polycyclic nucleophilic carbenes–synthesis, structure, and function AJ Arduengo Iii, LI Iconaru Dalton Transactions, 6903-6914, 2009 | 70 | 2009 |
A small molecule causes a population shift in the conformational landscape of an intrinsically disordered protein D Ban, LI Iconaru, A Ramanathan, J Zuo, RW Kriwacki Journal of the American Chemical Society 139 (39), 13692-13700, 2017 | 45 | 2017 |
Real‐Time Analysis of Folding upon Binding of a Disordered Protein by Using Dissolution DNP NMR Spectroscopy M Ragavan, LI Iconaru, CG Park, RW Kriwacki, C Hilty Angewandte Chemie International Edition 56 (25), 7070-7073, 2017 | 39 | 2017 |
Development of second-generation CDK2 inhibitors for the prevention of cisplatin-induced hearing loss RA Hazlitt, T Teitz, JD Bonga, J Fang, S Diao, L Iconaru, L Yang, ... Journal of medicinal chemistry 61 (17), 7700-7709, 2018 | 36 | 2018 |
Small molecule sequestration of the intrinsically disordered protein, p27Kip1, within soluble oligomers LI Iconaru, S Das, A Nourse, AA Shelat, J Zuo, RW Kriwacki Journal of molecular biology 433 (18), 167120, 2021 | 22 | 2021 |
Design, synthesis and evaluation of 2, 5-diketopiperazines as inhibitors of the MDM2-p53 interaction M Pettersson, M Quant, J Min, L Iconaru, RW Kriwacki, MB Waddell, ... PLoS one 10 (10), e0137867, 2015 | 22 | 2015 |
High-Throughput Screening Reveals Alsterpaullone, 2-Cyanoethyl as a Potent p27Kip1 Transcriptional Inhibitor BJ Walters, W Lin, S Diao, M Brimble, LI Iconaru, J Dearman, A Goktug, ... PloS one 9 (3), e91173, 2014 | 20 | 2014 |
8-Triazolylpurines: Towards fluorescent inhibitors of the MDM2/p53 interaction M Pettersson, D Bliman, J Jacobsson, JR Nilsson, J Min, L Iconaru, ... PLoS One 10 (5), e0124423, 2015 | 14 | 2015 |
Two Decades of IDPs; What have we Learned? R Kriwacki, DM Mitrea, A Follis, L Iconaru, J Cika, D Ban, A Philllips Biophysical Journal 112 (3), 12a-13a, 2017 | 3 | 2017 |
Fused polycyclic imidazoles LI Iconaru The University of Alabama Electronic Theses and Dissertations, 2009 | 2 | 2009 |
Small molecules that bind cyclin-dependent kinase inhibitor 1b (p27kip1) R Kriwacki, J Zuo, L Iconaru, S Das, A Shelat, B Young US Patent App. 17/438,857, 2022 | | 2022 |
A Quest for Small Molecule Inhibitors of the Cell Cycle Regulator, P27 LI Iconaru, A Shelat, J Zuo, RW Kriwacki Biophysical Journal 102 (3), 635a, 2012 | | 2012 |
Progress toward the stabilization of fused polycyclic nucleophilic carbenes AJ Arduengo III, LI Iconaru ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 238, 64-64, 2009 | | 2009 |
ORGN 389-Toward the stabilization of fused tricyclic-tris (carbenes) AJ Arduengo III, LI Iconaru ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 235, 2008 | | 2008 |