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Derek Richard
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Combination therapy with histone deacetylase inhibitors (HDACi) for the treatment of cancer: achieving the full therapeutic potential of HDACi
A Suraweera, KJ O’Byrne, DJ Richard
Frontiers in oncology 8, 92, 2018
6352018
PARP inhibitors: clinical relevance, mechanisms of action and tumor resistance
M Rose, JT Burgess, K O’Byrne, DJ Richard, E Bolderson
Frontiers in cell and developmental biology 8, 564601, 2020
4042020
Generation and characterisation of cisplatin-resistant non-small cell lung cancer cell lines displaying a stem-like signature
MP Barr, SG Gray, AC Hoffmann, RA Hilger, J Thomale, JD O’Flaherty, ...
PloS one 8 (1), e54193, 2013
3112013
Functions and therapeutic roles of exosomes in cancer
JA Tickner, AJ Urquhart, SA Stephenson, DJ Richard, KJ O’Byrne
Frontiers in oncology 4, 127, 2014
2832014
Single-stranded DNA-binding protein hSSB1 is critical for genomic stability
DJ Richard, E Bolderson, L Cubeddu, RIM Wadsworth, K Savage, ...
Nature 453 (7195), 677-681, 2008
2792008
Nucleophosmin: from structure and function to disease development
JK Box, N Paquet, MN Adams, D Boucher, E Bolderson, KJ O’Byrne, ...
BMC molecular biology 17, 1-12, 2016
2572016
Recent advances in cancer therapy targeting proteins involved in DNA double-strand break repair
E Bolderson, DJ Richard, BBS Zhou, KK Khanna
Clinical Cancer Research 15 (20), 6314-6320, 2009
2502009
Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks
E Bolderson, N Tomimatsu, DJ Richard, D Boucher, R Kumar, TK Pandita, ...
Nucleic acids research 38 (6), 1821-1831, 2010
2222010
Circulating tumour cells, their role in metastasis and their clinical utility in lung cancer
JD O’Flaherty, S Gray, JJ O’Leary, FH Blackhall, KJ O’Byrne
Lung Cancer, 2011
2102011
Identification of a BRCA1-mRNA splicing complex required for efficient DNA repair and maintenance of genomic stability
KI Savage, JJ Gorski, EM Barros, GW Irwin, L Manti, AJ Powell, ...
Molecular cell 54 (3), 445-459, 2014
1942014
The role of DNA repair pathways in cisplatin resistant lung cancer
S O’Grady, SP Finn, S Cuffe, DJ Richard, KJ O’Byrne, MP Barr
Cancer treatment reviews 40 (10), 1161-1170, 2014
1542014
The cancer stem-cell hypothesis: its emerging role in lung cancer biology and its relevance for future therapy
JD O’Flaherty, M Barr, D Fennell, D Richard, J Reynolds, J O’Leary, ...
Journal of thoracic oncology 7 (12), 1880-1890, 2012
1522012
BRCA1 deficiency exacerbates estrogen-induced DNA damage and genomic instability
KI Savage, KB Matchett, EM Barros, KM Cooper, GW Irwin, JJ Gorski, ...
Cancer research 74 (10), 2773-2784, 2014
1432014
Transcriptional regulation in response to oxygen and nitrate of the operons encoding the [NiFe] hydrogenases 1 and 2 of Escherichia coli
DJ Richard, G Sawers, F Sargent, L McWalter, DH Boxer
Microbiology 145 (10), 2903-2912, 1999
1381999
Chemotherapeutic compounds targeting the DNA double-strand break repair pathways: the good, the bad, and the promising
C Jekimovs, E Bolderson, A Suraweera, M Adams, KJ O’Byrne, ...
Frontiers in oncology 4, 86, 2014
1352014
Drug discovery approaches utilizing three-dimensional cell culture
SL Ryan, AM Baird, G Vaz, AJ Urquhart, hias Senge, DJ Richard, ...
Assay and drug development technologies 14 (1), 19-28, 2016
1292016
HSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage response
Y Li, E Bolderson, R Kumar, PA Muniandy, Y Xue, DJ Richard, ...
Journal of biological chemistry 284 (35), 23525-23531, 2009
1282009
Par4 is a coactivator for a splice isoform–specific transcriptional activation domain in WT1
DJ Richard, V Schumacher, B Royer-Pokora, SGE Roberts
Genes & development 15 (3), 328-339, 2001
1222001
Multiple human single-stranded DNA binding proteins function in genome maintenance: structural, biochemical and functional analysis
DJ Richard, E Bolderson, KK Khanna
Critical reviews in biochemistry and molecular biology 44 (2-3), 98-116, 2009
1202009
The emerging role of gas plasma in oncotherapy
X Dai, K Bazaka, DJ Richard, ERW Thompson, KK Ostrikov
Trends in biotechnology 36 (11), 1183-1198, 2018
1172018
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