Feasibility, biodistribution, and preliminary dosimetry in peptide-targeted radionuclide therapy of diverse adenocarcinomas using 177Lu-FAP-2286: first-in-humans results RP Baum, C Schuchardt, A Singh, M Chantadisai, FC Robiller, J Zhang, ... Journal of Nuclear Medicine 63 (3), 415-423, 2022 | 219 | 2022 |
Synthesis, 18F-Labeling, and in Vitro and in Vivo Studies of Bombesin Peptides Modified with Silicon-Based Building Blocks A Höhne, L Mu, M Honer, PA Schubiger, SM Ametamey, K Graham, ... Bioconjugate chemistry 19 (9), 1871-1879, 2008 | 182 | 2008 |
Silicon‐Based Building Blocks for One‐Step 18F‐Radiolabeling of Peptides for PET Imaging L Mu, A Höhne, PA Schubiger, SM Ametamey, K Graham, JE Cyr, ... Angewandte Chemie International Edition 47 (26), 4922-4925, 2008 | 143 | 2008 |
Preclinical evaluation of FAP-2286 for fibroblast activation protein targeted radionuclide imaging and therapy D Zboralski, A Hoehne, A Bredenbeck, A Schumann, M Nguyen, ... European journal of nuclear medicine and molecular imaging 49 (11), 3651-3667, 2022 | 132 | 2022 |
A PET imaging strategy to visualize activated T cells in acute graft-versus-host disease elicited by allogenic hematopoietic cell transplant JA Ronald, BS Kim, G Gowrishankar, M Namavari, IS Alam, A D'Souza, ... Cancer research 77 (11), 2893-2902, 2017 | 132 | 2017 |
Investigation of 6-[18F]-Fluoromaltose as a Novel PET Tracer for Imaging Bacterial Infection G Gowrishankar, M Namavari, EB Jouannot, A Hoehne, R Reeves, ... PloS one 9 (9), e107951, 2014 | 117 | 2014 |
Organofluorosilanes as Model Compounds for 18F‐Labeled Silicon‐Based PET Tracers and their Hydrolytic Stability: Experimental Data and Theoretical … A Höhne, L Yu, L Mu, M Reiher, U Voigtmann, U Klar, K Graham, ... Chemistry–A European Journal 15 (15), 3736-3743, 2009 | 89 | 2009 |
Antiviral drug ganciclovir is a potent inhibitor of microglial proliferation and neuroinflammation Z Ding, V Mathur, PP Ho, ML James, KM Lucin, A Hoehne, H Alabsi, ... Journal of Experimental Medicine 211 (2), 189-198, 2014 | 74 | 2014 |
[18F] GE-180 PET detects reduced microglia activation after LM11A-31 therapy in a mouse model of Alzheimer's disease ML James, NP Belichenko, AJ Shuhendler, A Hoehne, LE Andrews, ... Theranostics 7 (6), 1422, 2017 | 72* | 2017 |
PET imaging of tumor glycolysis downstream of hexokinase through noninvasive measurement of pyruvate kinase M2 TH Witney, ML James, B Shen, E Chang, C Pohling, N Arksey, A Hoehne, ... Science translational medicine 7 (310), 310ra169-310ra169, 2015 | 69 | 2015 |
Synthesis of 18 F-labelled cyclooxygenase-2 (COX-2) inhibitors via Stille reaction with 4-[18 F] fluoroiodobenzene as radiotracers for positron emission tomography (PET) FR Wüst, A Höhne, P Metz Organic & biomolecular chemistry 3 (3), 503-507, 2005 | 66 | 2005 |
Pilot preclinical and clinical evaluation of (4S)-4-(3-[18F] fluoropropyl)-L-glutamate (18F-FSPG) for PET/CT imaging of intracranial malignancies ES Mittra, N Koglin, C Mosci, M Kumar, A Hoehne, KV Keu, AH Iagaru, ... PLoS One 11 (2), e0148628, 2016 | 62 | 2016 |
A Systematic Comparison of 18F-C-SNAT to Established Radiotracer Imaging Agents for the Detection of Tumor Response to Treatment TH Witney, A Hoehne, RE Reeves, O Ilovich, M Namavari, B Shen, ... Clinical Cancer Research 21 (17), 3896-3905, 2015 | 61 | 2015 |
Proof of therapeutic efficacy of a 177Lu-labeled neurotensin receptor 1 antagonist in a colon carcinoma xenograft model J Schulz, M Rohracker, M Stiebler, J Goldschmidt, F Stöber, M Noriega, ... Journal of Nuclear Medicine 58 (6), 936-941, 2017 | 57 | 2017 |
Assessment of Tumor Redox Status through (S)-4-(3-[18F]fluoropropyl)-L-Glutamic Acid PET Imaging of System xc− Activity PN McCormick, HE Greenwood, M Glaser, ODK Maddocks, T Gendron, ... Cancer research 79 (4), 853-863, 2022 | 55 | 2022 |
Imaging B cells in a mouse model of multiple sclerosis using 64Cu-rituximab PET ML James, A Hoehne, AT Mayer, K Lechtenberg, M Moreno, ... Journal of Nuclear Medicine 58 (11), 1845-1851, 2017 | 44 | 2017 |
Synthesis of [18F]-labelled Maltose Derivatives as PET Tracers for Imaging Bacterial Infection M Namavari, G Gowrishankar, A Hoehne, E Jouannot, SS Gambhir Molecular imaging and biology 17, 168-176, 2015 | 43 | 2015 |
A 18F-Labeled Saxitoxin Derivative for in Vivo PET-MR Imaging of Voltage-Gated Sodium Channel Expression Following Nerve Injury A Hoehne, D Behera, WH Parsons, ML James, B Shen, P Borgohain, ... Journal of the American Chemical Society 135 (48), 18012-18015, 2013 | 40 | 2013 |
Discovery and validation of small-molecule heat-shock protein 90 inhibitors through multimodality molecular imaging in living subjects CT Chan, RE Reeves, R Geller, SS Yaghoubi, A Hoehne, ... Proceedings of the National Academy of Sciences 109 (37), E2476-E2485, 2012 | 35 | 2012 |
[18F]FSPG-PET reveals increased cystine/glutamate antiporter (xc-) activity in a mouse model of multiple sclerosis A Hoehne, ML James, IS Alam, JA Ronald, B Schneider, A D’Souza, ... Journal of neuroinflammation 15, 1-12, 2018 | 23 | 2018 |