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Martin R. Higgs
Martin R. Higgs
Institute of Cancer and Genomic Sciences, University of Birmingham
Verified email at bham.ac.uk - Homepage
Title
Cited by
Cited by
Year
PARP1 and PARP2 stabilise replication forks at base excision repair intermediates through Fbh1-dependent Rad51 regulation
G Ronson, AL Piberger, M Higgs, A Olsen, G Stewart, P McHugh, ...
Nature Communications, 243071, 2018
2042018
BOD1L is required to suppress deleterious resection of stressed replication forks
MR Higgs, JJ Reynolds, A Winczura, AN Blackford, V Borel, ES Miller, ...
Molecular cell 59 (3), 462-477, 2015
1872015
Hepatitis C virus proteins induce lipogenesis and defective triglyceride secretion in transgenic mice
H Lerat, HL Kammoun, I Hainault, E Mérour, MR Higgs, C Callens, ...
Journal of Biological Chemistry 284 (48), 33466-33474, 2009
1122009
Hepatitis C virus-induced activation of β-catenin promotes c-Myc expression and a cascade of pro-carcinogenetic events
MR Higgs, H Lerat, JM Pawlotsky
Oncogene 32 (39), 4683-4693, 2013
1002013
‘Liver let die’: oxidative DNA damage and hepatotropic viruses
MR Higgs, P Chouteau, H Lerat
Journal of General Virology 95 (5), 991-1004, 2014
962014
Histone methylation by SETD1A protects nascent DNA through the nucleosome chaperone activity of FANCD2
MR Higgs, K Sato, JJ Reynolds, S Begum, R Bayley, A Goula, A Vernet, ...
Molecular cell 71 (1), 25-41. e6, 2018
942018
Mutations in DONSON disrupt replication fork stability and cause microcephalic dwarfism
JJ Reynolds, LS Bicknell, P Carroll, MR Higgs, R Shaheen, JE Murray, ...
Nature genetics 49 (4), 537-549, 2017
882017
TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism
ME Harley, O Murina, A Leitch, MR Higgs, LS Bicknell, G Yigit, ...
Nature genetics 48 (1), 36-43, 2016
852016
Downregulation of Gadd45β expression by hepatitis C virus leads to defective cell cycle arrest
MR Higgs, H Lerat, JM Pawlotsky
Cancer research 70 (12), 4901-4911, 2010
702010
Characterization of SETD1A haploinsufficiency in humans and Drosophila defines a novel neurodevelopmental syndrome
J Kummeling, DE Stremmelaar, N Raun, MRF Reijnders, MH Willemsen, ...
Molecular psychiatry 26 (6), 2013-2024, 2021
502021
Mutational analysis of the herpes simplex virus type 1 DNA packaging protein UL33
F Beilstein, MR Higgs, ND Stow
Journal of virology 83 (17), 8938-8945, 2009
352009
Regulation of hepatitis C virus replication by nuclear translocation of nonstructural 5A protein and transcriptional activation of host genes
MA Maqbool, MR Imache, MR Higgs, S Carmouse, JM Pawlotsky, H Lerat
Journal of virology 87 (10), 5523-5539, 2013
342013
The UL15 protein of herpes simplex virus type 1 is necessary for the localization of the UL28 and UL33 proteins to viral DNA replication centres
MR Higgs, VG Preston, ND Stow
Journal of general virology 89 (7), 1709-1715, 2008
342008
Persistence of RNA transcription during DNA replication delays duplication of transcription start sites until G2/M
J Wang, P Rojas, J Mao, MM Sadurnì, O Garnier, S Xiao, MR Higgs, ...
Cell Reports 34 (7), 2021
322021
Animal models in the study of hepatitis C virus-associated liver pathologies
H Lerat, M Higgs, JM Pawlotsky
Expert review of gastroenterology & hepatology 5 (3), 341-352, 2011
302011
Cancer therapy and replication stress: forks on the road to perdition
P Kotsantis, RM Jones, MR Higgs, E Petermann
Advances in clinical chemistry 69, 91-138, 2015
292015
Bi-allelic variants in TONSL cause SPONASTRIME dysplasia and a spectrum of skeletal dysplasia phenotypes
LC Burrage, JJ Reynolds, NV Baratang, JB Phillips, J Wegner, ...
The American Journal of Human Genetics 104 (3), 422-438, 2019
272019
Hepatitis C virus induces a prediabetic state by directly impairing hepatic glucose metabolism in mice
H Lerat, MR Imache, J Polyte, A Gaudin, M Mercey, F Donati, ...
Journal of Biological Chemistry 292 (31), 12860-12873, 2017
272017
Germline RBBP8 variants associated with early-onset breast cancer compromise replication fork stability
R Zarrizi, MR Higgs, K Voßgröne, M Rossing, B Bertelsen, M Bose, ...
The Journal of clinical investigation 130 (8), 4069-4080, 2020
262020
A dual role for SAMHD1 in regulating HBV cccDNA and RT-dependent particle genesis
PAC Wing, T Davenne, J Wettengel, AG Lai, X Zhuang, A Chakraborty, ...
Life science alliance 2 (2), 2019
262019
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