The endothelin axis: emerging role in cancer J Nelson, A Bagnato, B Battistini, P Nisen Nature Reviews Cancer 3 (2), 110-116, 2003 | 708 | 2003 |
Endothelin-1 induces an angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo D Salani, G Taraboletti, L Rosanò, V Di Castro, P Borsotti, R Giavazzi, ... The American journal of pathology 157 (5), 1703-1711, 2000 | 466 | 2000 |
Endothelin 1 in cancer: biological implications and therapeutic opportunities L Rosanò, F Spinella, A Bagnato Nature Reviews Cancer 13 (9), 637-651, 2013 | 349 | 2013 |
Endothelin-1 induces vascular endothelial growth factor by increasing hypoxia-inducible factor-1α in ovarian carcinoma cells F Spinella, L Rosanò, V Di Castro, PG Natali, A Bagnato Journal of Biological Chemistry 277 (31), 27850-27855, 2002 | 311 | 2002 |
Expression of endothelin 1 and endothelin A receptor in ovarian carcinoma: evidence for an autocrine role in tumor growth A Bagnato, D Salani, V Di Castro, JR Wu-Wong, R Tecce, MR Nicotra, ... Cancer Research 59 (3), 720-727, 1999 | 281 | 1999 |
Role of endothelin-1 in neovascularization of ovarian carcinoma D Salani, V Di Castro, MR Nicotra, L Rosanò, R Tecce, A Venuti, ... The American journal of pathology 157 (5), 1537-1547, 2000 | 269 | 2000 |
The endothelin axis in cancer A Bagnato, L Rosanò The international journal of biochemistry & cell biology 40 (8), 1443-1451, 2008 | 257 | 2008 |
Endothelin-1 promotes epithelial-to-mesenchymal transition in human ovarian cancer cells L Rosanò, F Spinella, V Di Castro, MR Nicotra, S Dedhar, AG de Herreros, ... Cancer research 65 (24), 11649-11657, 2005 | 234 | 2005 |
Acquisition of chemoresistance and EMT phenotype is linked with activation of the endothelin A receptor pathway in ovarian carcinoma cells L Rosanò, R Cianfrocca, F Spinella, V Di Castro, MR Nicotra, A Lucidi, ... Clinical cancer research 17 (8), 2350-2360, 2011 | 219 | 2011 |
Emerging role of endothelin-1 in tumor angiogenesis A Bagnato, F Spinella Trends in Endocrinology & Metabolism 14 (1), 44-50, 2003 | 212 | 2003 |
Endothelin-1 induces tumor proteinase activation and invasiveness of ovarian carcinoma cells L Rosano, M Varmi, D Salani, V Di Castro, F Spinella, PG Natali, ... Cancer Research 61 (22), 8340-8346, 2001 | 211 | 2001 |
β-Arrestin links endothelin A receptor to β-catenin signaling to induce ovarian cancer cell invasion and metastasis L Rosano, R Cianfrocca, S Masi, F Spinella, V Di Castro, A Biroccio, ... Proceedings of the National Academy of Sciences 106 (8), 2806-2811, 2009 | 201 | 2009 |
Endothelin-1 protects ovarian carcinoma cells against paclitaxel-induced apoptosis: requirement for Akt activation D Del Bufalo, V Di Castro, A Biroccio, M Varmi, D Salani, L Rosanò, ... Molecular Pharmacology 61 (3), 524-532, 2002 | 189 | 2002 |
Transactivation of the epidermal growth factor receptor in endothelin-1-induced mitogenic signaling in human ovarian carcinoma cells F Vacca, A Bagnato, KJ Catt, R Tecce Cancer Research 60 (18), 5310-5317, 2000 | 174 | 2000 |
Endothelin receptors as novel targets in tumor therapy A Bagnato, PG Natali Journal of translational medicine 2, 1-9, 2004 | 162 | 2004 |
Activation of mitogenic signaling by endothelin 1 in ovarian carcinoma cells A Bagnato, R Tecce, V Di Castro, KJ Catt Cancer Research 57 (7), 1306-1311, 1997 | 161 | 1997 |
Endothelin B receptor blockade inhibits dynamics of cell interactions and communications in melanoma cell progression A Bagnato, L Rosanò, F Spinella, V Di Castro, R Tecce, PG Natali Cancer research 64 (4), 1436-1443, 2004 | 160 | 2004 |
Therapeutic targeting of the endothelin a receptor in human ovarian carcinoma L Rosano, F Spinella, D Salani, V Di Castro, A Venuti, MR Nicotra, ... Cancer Research 63 (10), 2447-2453, 2003 | 159 | 2003 |
Role of the endothelin axis and its antagonists in the treatment of cancer A Bagnato, M Loizidou, BR Pflug, J Curwen, J Growcott British journal of pharmacology 163 (2), 220-233, 2011 | 145 | 2011 |
Endothelin-1-induced prostaglandin E2-EP2, EP4 signaling regulates vascular endothelial growth factor production and ovarian carcinoma cell invasion F Spinella, L Rosanò, V Di Castro, PG Natali, A Bagnato Journal of Biological Chemistry 279 (45), 46700-46705, 2004 | 138 | 2004 |