Calculation of the electric potential in the active site cleft due to α-helix dipoles J Warwicker, HC Watson Journal of molecular biology 157 (4), 671-679, 1982 | 1174 | 1982 |
Protein–Sol: a web tool for predicting protein solubility from sequence M Hebditch, MA Carballo-Amador, S Charonis, R Curtis, J Warwicker Bioinformatics 33 (19), 3098-3100, 2017 | 550 | 2017 |
The RACK1 scaffold protein: a dynamic cog in cell response mechanisms A McCahill, J Warwicker, GB Bolger, MD Houslay, SJ Yarwood Molecular pharmacology 62 (6), 1261-1273, 2002 | 458 | 2002 |
Progress in the prediction of pKa values in proteins E Alexov, EL Mehler, N Baker, A M. Baptista, Y Huang, F Milletti, ... Proteins: structure, function, and bioinformatics 79 (12), 3260-3275, 2011 | 282 | 2011 |
TAPAS-1, a novel microdomain within the unique N-terminal region of the PDE4A1 cAMP-specific phosphodiesterase that allows rapid, Ca2+-triggered membrane association with … GS Baillie, E Huston, G Scotland, M Hodgkin, I Gall, AH Peden, ... Journal of Biological Chemistry 277 (31), 28298-28309, 2002 | 183 | 2002 |
The role of electrostatics in protein–protein interactions of a monoclonal antibody D Roberts, R Keeling, M Tracka, CF Van Der Walle, S Uddin, J Warwicker, ... Molecular pharmaceutics 11 (7), 2475-2489, 2014 | 179 | 2014 |
Visualization of poly(ADP-ribose) bound to PARG reveals inherent balance between exo- and endo-glycohydrolase activities E Barkauskaite, A Brassington, ES Tan, J Warwicker, MS Dunstan, ... Nature communications 4 (1), 2164, 2013 | 171 | 2013 |
Specific ion and buffer effects on protein–protein interactions of a monoclonal antibody D Roberts, R Keeling, M Tracka, CF Van Der Walle, S Uddin, J Warwicker, ... Molecular pharmaceutics 12 (1), 179-193, 2015 | 169 | 2015 |
Effect of phosphorylation on α-helix stability as a function of position CD Andrew, J Warwicker, GR Jones, AJ Doig Biochemistry 41 (6), 1897-1905, 2002 | 156 | 2002 |
Buried charged surface in proteins T Kajander, PC Kahn, SH Passila, DC Cohen, L Lehtiö, W Adolfsen, ... Structure 8 (11), 1203-1214, 2000 | 145 | 2000 |
Side‐chain conformational entropy at protein–protein interfaces C Cole, J Warwicker Protein Science 11 (12), 2860-2870, 2002 | 111 | 2002 |
Soluble expression of proteins correlates with a lack of positively-charged surface P Chan, RA Curtis, J Warwicker Scientific reports 3 (1), 3333, 2013 | 103 | 2013 |
Improved pKa calculations through flexibility based sampling of a water‐dominated interaction scheme J Warwicker Protein Science 13 (10), 2793-2805, 2004 | 102 | 2004 |
Charged residues next to transmembrane regions revisited:“Positive-inside rule” is complemented by the “negative inside depletion/outside enrichment rule” JA Baker, WC Wong, B Eisenhaber, J Warwicker, F Eisenhaber BMC biology 15, 1-29, 2017 | 101 | 2017 |
Simplified methods for pKa and acid pH-dependent stability estimation in proteins: removing dielectric and counterion boundaries J Warwicker Protein science 8 (2), 418-425, 1999 | 100 | 1999 |
A molecular model for the redox potential difference between thioredoxin and DsbA, based on electrostatics calculations PJ Gane, RB Freedman, J Warwicker Journal of molecular biology 249 (2), 376-387, 1995 | 94 | 1995 |
Electrostatic field of the large fragment of Escherichia coli DNA polymerase I J Warwicker, D Ollis, FM Richards, TA Steitz Journal of molecular biology 186 (3), 645-649, 1985 | 92 | 1985 |
A quantitative molecular model for modulation of mammalian translation by the eIF4E-binding protein 1 MM Karim, JMX Hughes, J Warwicker, GC Scheper, CG Proud, ... Journal of Biological Chemistry 276 (23), 20750-20757, 2001 | 91 | 2001 |
Electrostatic calculations and model‐building suggest that DNA bound to CAP is sharply bent J Warwicker, BP Engelman, TA Steitz Proteins: Structure, Function, and Bioinformatics 2 (4), 283-289, 1987 | 91 | 1987 |
Web-based display of protein surface and pH-dependent properties for assessing the developability of biotherapeutics M Hebditch, J Warwicker Scientific reports 9 (1), 1969, 2019 | 89 | 2019 |