Charles Swanton
Charles Swanton
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TitleCited byYear
Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, FC Abdalla, H Abeliovich, RT Abraham, A Acevedo-Arozena, ...
Autophagy 8 (4), 445-544, 2012
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
M Gerlinger, AJ Rowan, S Horswell, J Larkin, D Endesfelder, E Gronroos, ...
New England journal of medicine 366 (10), 883-892, 2012
The causes and consequences of genetic heterogeneity in cancer evolution
RA Burrell, N McGranahan, J Bartek, C Swanton
Nature 501 (7467), 338, 2013
Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
N McGranahan, AJS Furness, R Rosenthal, S Ramskov, R Lyngaa, ...
Science 351 (6280), 1463-1469, 2016
Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing
M Gerlinger, S Horswell, J Larkin, AJ Rowan, MP Salm, I Varela, R Fisher, ...
Nature genetics 46 (3), 225, 2014
Spatial and temporal diversity in genomic instability processes defines lung cancer evolution
EC de Bruin, N McGranahan, R Mitter, M Salm, DC Wedge, L Yates, ...
Science 346 (6206), 251-256, 2014
Genetic prognostic and predictive markers in colorectal cancer
A Walther, E Johnstone, C Swanton, R Midgley, I Tomlinson, D Kerr
Nature Reviews Cancer 9 (7), 489, 2009
Intratumor heterogeneity: evolution through space and time
C Swanton
Cancer research 72 (19), 4875-4882, 2012
Biological and therapeutic impact of intratumor heterogeneity in cancer evolution
N McGranahan, C Swanton
Cancer cell 27 (1), 15-26, 2015
Tracking the evolution of non–small-cell lung cancer
M Jamal-Hanjani, GA Wilson, N McGranahan, NJ Birkbak, TBK Watkins, ...
New England Journal of Medicine 376 (22), 2109-2121, 2017
Clonal heterogeneity and tumor evolution: past, present, and the future
N McGranahan, C Swanton
Cell 168 (4), 613-628, 2017
Cancer heterogeneity: implications for targeted therapeutics
R Fisher, L Pusztai, C Swanton
British journal of cancer 108 (3), 479, 2013
Replication stress links structural and numerical cancer chromosomal instability
RA Burrell, SE McClelland, D Endesfelder, P Groth, MC Weller, N Shaikh, ...
Nature 494 (7438), 492, 2013
Intratumor heterogeneity: seeing the wood for the trees
TA Yap, M Gerlinger, PA Futreal, L Pusztai, C Swanton
Science translational medicine 4 (127), 127ps10-127ps10, 2012
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
C Abbosh, NJ Birkbak, GA Wilson, M Jamal-Hanjani, T Constantin, ...
Nature 545 (7655), 446, 2017
Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs
C Swanton, M Marani, O Pardo, PH Warne, G Kelly, E Sahai, F Elustondo, ...
Cancer cell 11 (6), 498-512, 2007
Herpes viral cyclin/Cdk6 complexes evade inhibition by CDK inhibitor proteins
C Swanton, DJ Mann, B Fleckenstein, F Neipel, G Peters, N Jones
Nature 390 (6656), 184, 1997
How Darwinian models inform therapeutic failure initiated by clonal heterogeneity in cancer medicine
M Gerlinger, C Swanton
British journal of cancer 103 (8), 1139, 2010
Toward understanding and exploiting tumor heterogeneity
AA Alizadeh, V Aranda, A Bardelli, C Blanpain, C Bock, C Borowski, ...
Nature medicine 21 (8), 846, 2015
Chromosomal instability confers intrinsic multidrug resistance
AJX Lee, D Endesfelder, AJ Rowan, A Walther, NJ Birkbak, PA Futreal, ...
Cancer research 71 (5), 1858-1870, 2011
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