Ankur Chakravarthy
Ankur Chakravarthy
Postdoctoral Fellow, Princess Margaret Cancer Centre
Verified email at
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ChAMP: 450k chip analysis methylation pipeline
TJ Morris, LM Butcher, A Feber, AE Teschendorff, AR Chakravarthy, ...
Bioinformatics 30 (3), 428-430, 2014
APOBEC-mediated cytosine deamination links PIK3CA helical domain mutations to human papillomavirus-driven tumor development
S Henderson, A Chakravarthy, X Su, C Boshoff, TR Fenton
Cell reports 7 (6), 1833-1841, 2014
Sensitive tumour detection and classification using plasma cell-free DNA methylomes
SY Shen, R Singhania, G Fehringer, A Chakravarthy, MHA Roehrl, ...
Nature 563 (7732), 579-583, 2018
LSD1 ablation stimulates anti-tumor immunity and enables checkpoint blockade
W Sheng, MW LaFleur, TH Nguyen, S Chen, A Chakravarthy, JR Conway, ...
Cell 174 (3), 549-563. e19, 2018
Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma
M Lechner, T Fenton, J West, G Wilson, A Feber, S Henderson, C Thirlwell, ...
Genome medicine 5 (2), 1-16, 2013
The TRAIL-induced cancer secretome promotes a tumor-supportive immune microenvironment via CCR2
T Hartwig, A Montinaro, S von Karstedt, A Sevko, S Surinova, ...
Molecular cell 65 (4), 730-742. e5, 2017
Epigenetic therapy in immune-oncology
PA Jones, H Ohtani, A Chakravarthy, DD De Carvalho
Nature Reviews Cancer 19 (3), 151-161, 2019
TGF-β-associated extracellular matrix genes link cancer-associated fibroblasts to immune evasion and immunotherapy failure
A Chakravarthy, L Khan, NP Bensler, P Bose, DD De Carvalho
Nature communications 9 (1), 1-10, 2018
Human papillomavirus drives tumor development throughout the head and neck: improved prognosis is associated with an immune response largely restricted to the oropharynx
A Chakravarthy, S Henderson, SM Thirdborough, CH Ottensmeier, X Su, ...
Journal of Clinical Oncology 34 (34), 4132, 2016
Pan-cancer deconvolution of tumour composition using DNA methylation
A Chakravarthy, A Furness, K Joshi, E Ghorani, K Ford, MJ Ward, EV King, ...
Nature communications 9 (1), 1-13, 2018
Apoptotic cell–induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans
R Shinde, K Hezaveh, MJ Halaby, A Kloetgen, A Chakravarthy, ...
Nature immunology 19 (6), 571-582, 2018
Frequent HPV-independent p16/INK4A overexpression in head and neck cancer
M Lechner, AR Chakravarthy, V Walter, L Masterson, A Feber, A Jay, ...
Oral oncology 83, 32-37, 2018
CSN1 somatic mutations in penile squamous cell carcinoma
A Feber, DC Worth, A Chakravarthy, P de Winter, K Shah, M Arya, ...
Cancer research 76 (16), 4720-4727, 2016
NOX4 inhibition potentiates immunotherapy by overcoming cancer-associated fibroblast-mediated CD8 T-cell exclusion from tumors
K Ford, CJ Hanley, M Mellone, C Szyndralewiez, F Heitz, P Wiesel, ...
Cancer Research 80 (9), 1846-1860, 2020
GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment
MJ Halaby, K Hezaveh, S Lamorte, A Kloetgen, BL MacLeod, M Guo, ...
Science immunology 4 (42), 2019
Detection and discrimination of intracranial tumors using plasma cell-free DNA methylomes
F Nassiri, A Chakravarthy, S Feng, SY Shen, R Nejad, JA Zuccato, ...
Nature Medicine 26 (7), 1044-1047, 2020
Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes
PV Nuzzo, JE Berchuck, K Korthauer, S Spisak, AH Nassar, S Abou Alaiwi, ...
Nature medicine 26 (7), 1041-1043, 2020
When defense turns into attack: Antiviral cytidine deaminases linked to somatic mutagenesis in HPV-associated cancer
S Henderson, A Chakravarthy, T Fenton
Molecular & cellular oncology 1 (1), e29914, 2014
When defense turns into attack: Antiviral cytidine deaminases linked to somatic mutagenesis in HPV-associated cancer
S Henderson, A Chakravarthy, T Fenton
Molecular & cellular oncology 1 (1), e29914, 2014
The cancer awareness assessment project: A small-scale survey across people with different levels of education in Mysore, India
A Sheshachalam, AR Chakravarthy
Indian Journal of Cancer 52 (1), 153, 2015
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