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Blake E. Smith
Blake E. Smith
Harvard Medical School
Verified email at hms.harvard.edu - Homepage
Title
Cited by
Cited by
Year
Lessons in PROTAC design from selective degradation with a promiscuous warhead
DP Bondeson, BE Smith, GM Burslem, AD Buhimschi, J Hines, ...
Cell chemical biology 25 (1), 78-87. e5, 2018
6662018
The advantages of targeted protein degradation over inhibition: an RTK case study
GM Burslem, BE Smith, AC Lai, S Jaime-Figueroa, DC McQuaid, ...
Cell chemical biology 25 (1), 67-77. e3, 2018
5272018
Differential PROTAC substrate specificity dictated by orientation of recruited E3 ligase
BE Smith, SL Wang, S Jaime-Figueroa, A Harbin, J Wang, BD Hamman, ...
Nature communications 10 (1), 131, 2019
3902019
Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth
J Sangodkar, A Perl, R Tohme, J Kiselar, DB Kastrinsky, N Zaware, ...
The Journal of clinical investigation 127 (6), 2081-2090, 2017
1802017
Antigen identification and high-throughput interaction mapping by reprogramming viral entry
CS Dobson, AN Reich, S Gaglione, BE Smith, EJ Kim, J Dong, L Ronsard, ...
Nature methods 19 (4), 449-460, 2022
392022
A facile synthesis of ligands for the von Hippel–Lindau E3 ligase
C Steinebach, SA Voell, LP Vu, A Bricelj, I Sosič, G Schnakenburg, ...
Synthesis 52 (17), 2521-2527, 2020
182020
An In Vitro Pull-down Assay of the E3 Ligase: PROTAC: Substrate Ternary Complex to Identify Effective PROTACs
DP Bondeson, BE Smith, AD Buhimschi
Targeted Protein Degradation: Methods and Protocols, 135-150, 2021
22021
A Biomaterial Platform for T Cell-Specific Gene Delivery
S Pandit, BE Smith, ME Birnbaum, Y Brudno
Acta Biomaterialia, 2024
12024
Re-centauring T cell antigen discovery around CD4+ T cells
BE Smith, AO Chan, ME Birnbaum
Cell Reports Methods 4 (1), 2024
2024
1232 Engineering a pseudotyped lentiviral platform to enable lineage-specific transduction of immune cells
B Smith, S Dougan, M Birnbaum
Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022
2022
Abstract A218: Simultaneous inhibition of both the PI3K-AKT and MAPK-ERK pathways using a single small molecule based approach for the treatment of advanced cancer.
N Dhawan, B Smith, J Sangodkar, V Gidwani, D Kastrinsky, M Ohlmeyer, ...
Molecular Cancer Therapeutics 10 (11_Supplement), A218-A218, 2011
2011
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