| Antibiotics that target mitochondria effectively eradicate cancer stem cells, across multiple tumor types: treating cancer like an infectious disease R Lamb, B Ozsvari, CL Lisanti, HB Tanowitz, A Howell, ... Oncotarget 6 (7), 4569, 2015 | 500 | 2015 |
| Mutation screening of the macrophage migration inhibitory factor gene: positive association of a functional polymorphism of macrophage migration inhibitory factor with juvenile … R Donn, Z Alourfi, F De Benedetti, C Meazza, E Zeggini, M Lunt, ... Arthritis & Rheumatism 46 (9), 2402-2409, 2002 | 334 | 2002 |
| Functional and prognostic relevance of the− 173 polymorphism of the macrophage migration inhibitory factor gene in systemic‐onset juvenile idiopathic arthritis F De Benedetti, C Meazza, M Vivarelli, F Rossi, A Pistorio, R Lamb, ... Arthritis & Rheumatism 48 (5), 1398-1407, 2003 | 253 | 2003 |
| Mitochondria as new therapeutic targets for eradicating cancer stem cells: Quantitative proteomics and functional validation via MCT1/2 inhibition R Lamb, H Harrison, J Hulit, DL Smith, MP Lisanti, F Sotgia Oncotarget 5 (22), 11029, 2014 | 207 | 2014 |
| Repurposing atovaquone: targeting mitochondrial complex III and OXPHOS to eradicate cancer stem cells M Fiorillo, R Lamb, HB Tanowitz, L Mutti, M Krstic-Demonacos, ... Oncotarget 7 (23), 34084, 2016 | 205 | 2016 |
| Mitochondria “fuel” breast cancer metabolism: fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells F Sotgia, D Whitaker-Menezes, UE Martinez-Outschoorn, AF Salem, ... Cell cycle 11 (23), 4390-4401, 2012 | 184 | 2012 |
| A functional promoter haplotype of macrophage migration inhibitory factor is linked and associated with juvenile idiopathic arthritis R Donn, Z Alourfi, E Zeggini, R Lamb, F Jury, M Lunt, ... Arthritis & Rheumatism 50 (5), 1604-1610, 2004 | 169 | 2004 |
| Wnt pathway activity in breast cancer sub-types and stem-like cells R Lamb, MP Ablett, K Spence, G Landberg, AH Sims, RB Clarke PloS one 8 (7), e67811, 2013 | 161 | 2013 |
| Mitochondrial mass, a new metabolic biomarker for stem-like cancer cells: Understanding WNT/FGF-driven anabolic signaling R Lamb, G Bonuccelli, B Ozsvári, M Peiris-Pagès, M Fiorillo, DL Smith, ... Oncotarget 6 (31), 30453, 2015 | 134 | 2015 |
| Bedaquiline, an FDA-approved antibiotic, inhibits mitochondrial function and potently blocks the proliferative expansion of stem-like cancer cells (CSCs) M Fiorillo, R Lamb, HB Tanowitz, AR Cappello, UE Martinez-Outschoorn, ... Aging (Albany NY) 8 (8), 1593, 2016 | 125 | 2016 |
| Macrophage migration inhibitory factor (MIF) gene polymorphism is associated with susceptibility to but not severity of inflammatory polyarthritis A Barton, R Lamb, D Symmons, A Silman, W Thomson, J Worthington, ... Genes & Immunity 4 (7), 487-491, 2003 | 120 | 2003 |
| Doxycycline down-regulates DNA-PK and radiosensitizes tumor initiating cells: Implications for more effective radiation therapy R Lamb, M Fiorillo, A Chadwick, B Ozsvari, KJ Reeves, DL Smith, ... Oncotarget 6 (16), 14005, 2015 | 111 | 2015 |
| Cell cycle regulators cyclin D1 and CDK4/6 have estrogen receptor-dependent divergent functions in breast cancer migration and stem cell-like activity R Lamb, S Lehn, L Rogerson, RB Clarke, G Landberg Cell cycle 12 (15), 2384-2394, 2013 | 103 | 2013 |
| Mitochondrial dysfunction in breast cancer cells prevents tumor growth: understanding chemoprevention with metformin R Sanchez-Alvarez, UE Martinez-Outschoorn, R Lamb, J Hulit, A Howell, ... Cell Cycle 12 (1), 172-182, 2013 | 103 | 2013 |
| Downregulation of miR-92a is associated with aggressive breast cancer features and increased tumour macrophage infiltration S Nilsson, C Möller, K Jirström, A Lee, S Busch, R Lamb, G Landberg PloS one 7 (4), e36051, 2012 | 100 | 2012 |
| Epidermal Notch1 recruits RORγ+ group 3 innate lymphoid cells to orchestrate normal skin repair Z Li, T Hodgkinson, EJ Gothard, S Boroumand, R Lamb, I Cummins, ... Nature communications 7 (1), 11394, 2016 | 93 | 2016 |
| BRCA1 mutations drive oxidative stress and glycolysis in the tumor microenvironment: implications for breast cancer prevention with antioxidant therapies UE Martinez-Outschoorn, R Balliet, Z Lin, D Whitaker-Menezes, RC Birbe, ... Cell cycle 11 (23), 4402-4413, 2012 | 91 | 2012 |
| Autoinflammatory genes and susceptibility to psoriatic juvenile idiopathic arthritis TG Day, AV Ramanan, A Hinks, R Lamb, J Packham, C Wise, M Punaro, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2008 | 85 | 2008 |
| Down-regulation of the oncogene cyclin D1 increases migratory capacity in breast cancer and is linked to unfavorable prognostic features S Lehn, NP Tobin, P Berglund, K Nilsson, AH Sims, K Jirström, ... The American journal of pathology 177 (6), 2886-2897, 2010 | 79 | 2010 |
| Cigarette smoke metabolically promotes cancer, via autophagy and premature aging in the host stromal microenvironment AF Salem, MS Al-Zoubi, D Whitaker-Menezes, UE Martinez-Outschoorn, ... Cell Cycle 12 (5), 818-825, 2013 | 72 | 2013 |
