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Dariusz Lachowski
Dariusz Lachowski
PhD, Department of Bioengineering, Imperial College London
Verified email at imperial.ac.uk
Title
Cited by
Cited by
Year
Matrix stiffness induces epithelial–mesenchymal transition and promotes chemoresistance in pancreatic cancer cells
AJ Rice, E Cortes, D Lachowski, BCH Cheung, SA Karim, JP Morton, ...
Oncogenesis 6 (7), e352-e352, 2017
4572017
ATRA mechanically reprograms pancreatic stellate cells to suppress matrix remodelling and inhibit cancer cell invasion
A Chronopoulos, B Robinson, M Sarper, E Cortes, V Auernheimer, ...
Nature communications 7 (1), 12630, 2016
2292016
FAK controls the mechanical activation of YAP, a transcriptional regulator required for durotaxis
D Lachowski, E Cortes, B Robinson, A Rice, K Rombouts, ...
The FASEB Journal 32 (2), 1099-1107, 2018
1642018
The guidance receptor plexin D1 is a mechanosensor in endothelial cells
V Mehta, KL Pang, D Rozbesky, K Nather, A Keen, D Lachowski, Y Kong, ...
Nature 578 (7794), 290-295, 2020
1322020
Substrate rigidity controls activation and durotaxis in pancreatic stellate cells
D Lachowski, E Cortes, D Pink, A Chronopoulos, SA Karim, J P. Morton, ...
Scientific reports 7 (1), 2506, 2017
1242017
Matrix stiffness modulates the activity of MMP-9 and TIMP-1 in hepatic stellate cells to perpetuate fibrosis
D Lachowski, E Cortes, A Rice, D Pinato, K Rombouts, ...
Scientific reports 9 (1), 7299, 2019
1182019
Syndecan-4 tunes cell mechanics by activating the kindlin-integrin-RhoA pathway
A Chronopoulos, SD Thorpe, E Cortes, D Lachowski, AJ Rice, ...
Nature materials 19 (6), 669-678, 2020
762020
Tamoxifen mechanically reprograms the tumor microenvironment via HIF‐1A and reduces cancer cell survival
E Cortes, D Lachowski, B Robinson, M Sarper, JS Teppo, SD Thorpe, ...
EMBO reports 20 (1), e46557, 2019
722019
Mechanotransduction in talin through the interaction of the R8 domain with DLC1
AWM Haining, R Rahikainen, E Cortes, D Lachowski, A Rice, ...
PLoS biology 16 (7), e2005599, 2018
662018
GPER is a mechanoregulator of pancreatic stellate cells and the tumor microenvironment
E Cortes, M Sarper, B Robinson, D Lachowski, A Chronopoulos, ...
EMBO reports 20 (1), e46556, 2019
652019
Retinoic acid receptor‐β is downregulated in hepatocellular carcinoma and cirrhosis and its expression inhibits myosin‐driven activation and durotaxis in hepatic stellate cells
E Cortes, D Lachowski, A Rice, A Chronopoulos, B Robinson, S Thorpe, ...
Hepatology 69 (2), 785-802, 2019
59*2019
Tamoxifen mechanically deactivates hepatic stellate cells via the G protein-coupled estrogen receptor
E Cortes, D Lachowski, A Rice, SD Thorpe, B Robinson, G Yeldag, ...
Oncogene 38 (16), 2910-2922, 2019
462019
Substrate Stiffness-Driven Membrane Tension Modulates Vesicular Trafficking via Caveolin-1
D Lachowski, C Matellan, S Gopal, E Cortes, BK Robinson, A Saiani, ...
ACS nano 16 (3), 4322-4337, 2022
222022
GPER activation inhibits cancer cell mechanotransduction and basement membrane invasion via RhoA
A Rice, E Cortes, D Lachowski, P Oertle, C Matellan, SD Thorpe, R Ghose, ...
Cancers 12 (2), 289, 2020
182020
Self-assembling polypeptide hydrogels as a platform to recapitulate the tumor microenvironment
D Lachowski, C Matellan, E Cortes, A Saiani, AF Miller, ...
Cancers 13 (13), 3286, 2021
142021
G Protein-Coupled Estrogen Receptor Regulates Actin Cytoskeleton Dynamics to Impair Cell Polarization
D Lachowski, E Cortes, C Matellan, A Rice, DA Lee, S Thorpe, ...
Frontiers in Cell and Developmental Biology 8, 1127, 2020
102020
RGD density along with substrate stiffness regulate hPSC hepatocyte functionality through YAP signalling
SJI Blackford, TL Tracy, MDA Norman, AM Syanda, M Manolakakis, ...
Biomaterials 293, 121982, 2023
72023
Highly specific and non-invasive imaging of Piezo1-dependent activity across scales using GenEPi
S Yaganoglu, K Kalyviotis, C Vagena-Pantoula, D Jülich, BM Gaub, ...
nature communications 14 (1), 4352, 2023
42023
Retinoic acid receptor β modulates mechanosensing and invasion in pancreatic cancer cells via myosin light chain 2
C Matellan, D Lachowski, E Cortes, KN Chiam, A Krstic, SD Thorpe, ...
Oncogenesis 12 (1), 23, 2023
32023
Implementation of a basement membrane invasion assay using mesenteric tissue
R Ghose, AJ Rice, E Cortes, U Ghose, D Lachowski, A del Rio Hernandez
Academic Press, 2019
32019
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