Multiple pathways involved in the biosynthesis of anandamide J Liu, L Wang, J Harvey-White, BX Huang, HY Kim, S Luquet, RD Palmiter, ... Neuropharmacology 54 (1), 1-7, 2008 | 363 | 2008 |
Activation of cannabinoid receptor 2 attenuates leukocyte–endothelial cell interactions and blood–brain barrier dysfunction under inflammatory conditions SH Ramirez, J Haskó, A Skuba, S Fan, H Dykstra, R McCormick, ... Journal of Neuroscience 32 (12), 4004-4016, 2012 | 256 | 2012 |
CB1 cannabinoid receptor‐mediated modulation of food intake in mice JL Wiley, JJ Burston, DC Leggett, OO Alekseeva, RK Razdan, ... British journal of pharmacology 145 (3), 293-300, 2005 | 238 | 2005 |
Development of the first potent and specific inhibitors of endocannabinoid biosynthesis T Bisogno, MG Cascio, B Saha, A Mahadevan, P Urbani, A Minassi, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2006 | 153 | 2006 |
Highly selective CB1 cannabinoid receptor ligands and novel CB1/VR1 vanilloid receptor “hybrid” ligands V Di Marzo, T Bisogno, L De Petrocellis, I Brandi, RG Jefferson, ... Biochemical and biophysical research communications 281 (2), 444-451, 2001 | 152 | 2001 |
The monoacylglycerol lipase inhibitor JZL184 suppresses inflammatory pain in the mouse carrageenan model S Ghosh, LE Wise, Y Chen, R Gujjar, A Mahadevan, BF Cravatt, ... Life sciences 92 (8-9), 498-505, 2013 | 136 | 2013 |
The CB2 cannabinoid receptor-selective agonist O-3223 reduces pain and inflammation without apparent cannabinoid behavioral effects SG Kinsey, A Mahadevan, B Zhao, H Sun, PS Naidu, RK Razdan, ... Neuropharmacology 60 (2-3), 244-251, 2011 | 121 | 2011 |
A structure/activity relationship study on arvanil, an endocannabinoid and vanilloid hybrid V Di Marzo, G Griffin, L De Petrocellis, I Brandi, T Bisogno, W Williams, ... Journal of Pharmacology and Experimental therapeutics 300 (3), 984-991, 2002 | 111 | 2002 |
Novel cannabinol probes for CB1 and CB2 cannabinoid receptors A Mahadevan, C Siegel, BR Martin, ME Abood, I Beletskaya, RK Razdan Journal of medicinal chemistry 43 (20), 3778-3785, 2000 | 110 | 2000 |
Inhibition of monoacylglycerol lipase and fatty acid amide hydrolase by analogues of 2‐arachidonoylglycerol N Ghafouri, G Tiger, RK Razdan, A Mahadevan, RG Pertwee, BR Martin, ... British journal of pharmacology 143 (6), 774-784, 2004 | 109 | 2004 |
Inhibition of monoacylglycerol lipase attenuates nonsteroidal anti-inflammatory drug-induced gastric hemorrhages in mice SG Kinsey, DK Nomura, ST O'Neal, JZ Long, A Mahadevan, BF Cravatt, ... Journal of Pharmacology and Experimental Therapeutics 338 (3), 795-802, 2011 | 107 | 2011 |
Targeting multiple cannabinoid anti‐tumour pathways with a resorcinol derivative leads to inhibition of advanced stages of breast cancer R Murase, R Kawamura, E Singer, A Pakdel, P Sarma, J Judkins, ... British journal of pharmacology 171 (19), 4464-4477, 2014 | 97 | 2014 |
6-Azidohex-2-yne-cannabidiol: a potential neutral, competitive cannabinoid CB1 receptor antagonist A Thomas, RA Ross, B Saha, A Mahadevan, RK Razdan, RG Pertwee European journal of pharmacology 487 (1-3), 213-221, 2004 | 93 | 2004 |
Inhibition of Cytosolic Phospholipase A2α: Hit to Lead Optimization JC McKew, MA Foley, P Thakker, ML Behnke, FE Lovering, FW Sum, ... Journal of medicinal chemistry 49 (1), 135-158, 2006 | 89 | 2006 |
Novel Pyrazole Cannabinoids: Insights into CB1Receptor Recognition and Activation JL Wiley, RG Jefferson, MC Grier, A Mahadevan, RK Razdan, BR Martin Journal of Pharmacology and Experimental Therapeutics 296 (3), 1013-1022, 2001 | 85 | 2001 |
A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2‐arachidonoylglycerol with potential anti‐obesity effects T Bisogno, A Mahadevan, R Coccurello, JW Chang, M Allarà, Y Chen, ... British journal of pharmacology 169 (4), 784-793, 2013 | 81 | 2013 |
Pyrazole cannabinoid agonist and antagonists BR Martin, RK Razdan, A Mahadevan US Patent 6,509,367, 2003 | 81 | 2003 |
New potent and selective inhibitors of anandamide reuptake with antispastic activity in a mouse model of multiple sclerosis A Ligresti, MG Cascio, G Pryce, S Kulasegram, I Beletskaya, ... British journal of pharmacology 147 (1), 83-91, 2006 | 75 | 2006 |
A general method for C3 reductive alkylation of indoles A Mahadevan, H Sard, M Gonzalez, JC McKew Tetrahedron letters 44 (24), 4589-4591, 2003 | 72 | 2003 |
Resorcinol derivatives: a novel template for the development of cannabinoid CB1/CB2 and CB2-selective agonists JL Wiley, ID Beletskaya, EW Ng, Z Dai, PJ Crocker, A Mahadevan, ... Journal of Pharmacology and Experimental Therapeutics 301 (2), 679-689, 2002 | 71 | 2002 |