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Savita K Sharma
Savita K Sharma
Principal Scientis II, In Vitro ADME
Verified email at crl.com
Title
Cited by
Cited by
Year
Oxygen Activation by Co(II) and a Redox Non-Innocent Ligand: Spectroscopic Characterization of a Radical–Co(II)–Superoxide Complex with Divergent Catalytic Reactivity
BJF Corcos A. R, Villanueva O, Walroth RC, Sharma SK, Bacsa J, Lancaster KM ...
J. Am. Chem. Soc., 2016, 138 (6), 1796-1799, 2016
852016
A Selective Stepwise Heme Oxygenase Model System: An Iron(IV)-Oxo Porphyrin π-Cation Radical Leads to a Verdoheme-Type Compound via an Isoporphyrin Intermediate
I Garcia-Bosch, SK Sharma, KD Karlin *
J. Am. Chem. Soc.,, 2013
442013
A Six-Coordinate Peroxynitrite Low-Spin Iron(III) Porphyrinate Complex—The Product of the Reaction of Nitrogen Monoxide (·NO(g)) with a Ferric-Superoxide Species
SK Sharma, AW Schaefer, H Lim, H Matsumura, P Moënne-Loccoz, ...
J. Am. Chem. Soc., 2017 139 (48), 17421, 2017
412017
Catalytic dioxygen activation by Co (II) complexes employing a coordinatively versatile ligand scaffold
SK Sharma, PS May, MB Jones, S Lense, KI Hardcastle, CE MacBeth
Chemical communications 47 (6), 1827-1829, 2011
402011
Critical Aspects of Heme–Peroxo–Cu Complex Structure and Nature of Proton Source Dictate Metal–Operoxo Breakage versus Reductive O–O Cleavage Chemistry
SM Adam, I Garcia-Bosch, AW Schaefer, SK Sharma, MA Siegler, ...
Journal of the American Chemical Society 139 (1), 472-481, 2017
392017
A "Naked" Fe-III-(O-2(2-))-Cu-II Species Allows for Structural and Spectroscopic Tuning of Low-Spin Heme-Peroxo-Cu Complexes
I Garcia-Bosch, SM Adam, AW Schaefer, SK Sharma, RL Peterson, ...
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 137 (3), 1032-1035, 2015
392015
Small molecule and peptide-based CXCR4 modulators as therapeutic agents. A patent review for the period from 2010 to 2018.
YA Tahirovic, S Pelly, E Jecs, EJ Miller, SK Sharma, DC Liotta, LJ Wilson
Expert Opinion on Therapeutic Patents, 2019
342019
Nickel and copper complexes with few amide-based macrocyclic and open-chain ligands
M Munjal, S Kumar, SK Sharma, R Gupta
Inorganica Chimica Acta 377 (1), 144-154, 2011
272011
Effect of Ligand Architecture on the Structure and Properties of Square‐Planar Nickel (II) Complexes of Amide‐Based Macrocycles
SK Sharma, S Upreti, R Gupta
European journal of inorganic chemistry 2007 (20), 3247-3259, 2007
252007
The Effect of Ligand Architecture on the Structure and Properties of Nickel and Copper Complexes of Amide‐Based Macrocycles
SK Sharma, G Hundal, R Gupta
European Journal of Inorganic Chemistry 2010 (4), 621-636, 2010
182010
Studies on the structure and properties of nickel complexes in a set of amide-based 13-membered macrocyclic ligands
SK Sharma, R Gupta
Inorganica Chimica Acta 376 (1), 95-104, 2011
152011
Reactions of a heme-superoxo complex toward a cuprous chelate and center dot NO(g): CcO and NOD chemistry
SK Sharma, PJ Rogler, KD Karlin
JOURNAL OF PORPHYRINS AND PHTHALOCYANINES 19 (1-3), 352-360, 2015
132015
New heme–dioxygen and carbon monoxide adducts using pyridyl or imidazolyl tailed porphyrins
Y Li, SK Sharma, KD Karlin
Polyhedron 58, 190-196, 2013
132013
Isocyanide or nitrosyl complexation to hemes with varying tethered axial base ligand donors: synthesis and characterization
SK Sharma, H Kim, PJ Rogler, M A Siegler, KD Karlin
JBIC Journal of Biological Inorganic Chemistry 21, 729-743, 2016
112016
Effect of irradiation on the volatile compounds of shrimp (Solenocera choprii).
SK Sharma, S Basu, AS Gholap
112007
Accelerated discovery of potent fusion inhibitors for respiratory syncytial virus
N Pribut, TM Kaiser, RJ Wilson, E Jecs, ZW Dentmon, SC Pelly, S Sharma, ...
ACS infectious diseases 6 (5), 922-929, 2020
102020
ω-Functionalized lipid prodrugs of HIV NtRTI tenofovir with enhanced pharmacokinetic properties
N Pribut, M D’Erasmo, M Dasari, KE Giesler, S Iskandar, SK Sharma, ...
Journal of Medicinal Chemistry 64 (17), 12917-12937, 2021
92021
Synthesis and biological evaluation of 5′-C-methyl nucleotide prodrugs for treating HCV infections
M Dasari, P Ma, SC Pelly, SK Sharma, DC Liotta
Bioorganic & Medicinal Chemistry Letters 30 (23), 127539, 2020
92020
Accelerated discovery of novel ponatinib analogs with improved properties for the treatment of parkinson’s disease
TM Kaiser, ZW Dentmon, CE Dalloul, SK Sharma, DC Liotta
ACS Medicinal Chemistry Letters 11 (4), 491-496, 2020
82020
Heme−Cu Binucleating Ligand Supports Heme/O2 and FeII −CuI /O2 Reactivity Providing High- and Low-Spin FeIII−Peroxo−CuII Complexes
H Kim, SK Sharma, AW Schaefer, EI Solomon, KD Karlin
Inorganic Chemistry 58 (22), 15423 - 15432, 2019
82019
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