Juliane Liepe
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A large fraction of HLA class I ligands are proteasome-generated spliced peptides
J Liepe, F Marino, J Sidney, A Jeko, DE Bunting, A Sette, PM Kloetzel, ...
Science 354 (6310), 354-358, 2016
A framework for parameter estimation and model selection from experimental data in systems biology using approximate Bayesian computation
J Liepe, P Kirk, S Filippi, T Toni, CP Barnes, MPH Stumpf
Nature protocols 9 (2), 439-456, 2014
Maximizing the information content of experiments in systems biology
J Liepe, S Filippi, M Komorowski, MPH Stumpf
PLoS computational biology 9 (1), e1002888, 2013
ABC-SysBio—approximate Bayesian computation in Python with GPU support
J Liepe, C Barnes, E Cule, K Erguler, P Kirk, T Toni, MPH Stumpf
Bioinformatics 26 (14), 1797-1799, 2010
Proteasome isoforms exhibit only quantitative differences in cleavage and epitope generation
M Mishto, J Liepe, K Textoris‐Taube, C Keller, P Henklein, M Weberruß, ...
European Journal of Immunology 44 (12), 3508-3521, 2014
GPU accelerated biochemical network simulation
Y Zhou, J Liepe, X Sheng, MPH Stumpf, C Barnes
Bioinformatics 27 (6), 874-876, 2011
The 20S proteasome splicing activity discovered by SpliceMet
J Liepe, M Mishto, K Textoris-Taube, K Janek, C Keller, P Henklein, ...
PLOS Computational Biology 6 (6), e1000830, 2010
Post-translational peptide splicing and T cell responses
M Mishto, J Liepe
Trends in Immunology 38 (12), 904-915, 2017
Mapping the MHC class I–spliced immunopeptidome of cancer cells
J Liepe, J Sidney, FKM Lorenz, A Sette, M Mishto
Cancer immunology research 7 (1), 62-76, 2019
Systems analysis of the dynamic inflammatory response to tissue damage reveals spatiotemporal properties of the wound attractant gradient
H Weavers, J Liepe, A Sim, W Wood, P Martin, MPH Stumpf
Current Biology 26 (15), 1975-1989, 2016
Information theory and signal transduction systems: from molecular information processing to network inference
SS Mc Mahon, A Sim, S Filippi, R Johnson, J Liepe, D Smith, MPH Stumpf
Seminars in cell & developmental biology 35, 98-108, 2014
Multi-level strategy for identifying proteasome-catalyzed spliced epitopes targeted by CD8+ T cells during bacterial infection
ACM Platteel, J Liepe, K Textoris-Taube, C Keller, P Henklein, ...
Cell reports 20 (5), 1242-1253, 2017
Quantitative time-resolved analysis reveals intricate, differential regulation of standard-and immuno-proteasomes
J Liepe, HG Holzhütter, E Bellavista, PM Kloetzel, MPH Stumpf, M Mishto
Elife 4, e07545, 2015
Extracellular proteasome-osteopontin circuit regulates cell migration with implications in multiple sclerosis
C Dianzani, E Bellavista, J Liepe, C Verderio, M Martucci, A Santoro, ...
Scientific reports 7 (1), 43718, 2017
An in silico—in vitro Pipeline Identifying an HLA-A*02:01+ KRAS G12V+ Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients
M Mishto, A Mansurkhodzhaev, G Ying, A Bitra, RA Cordfunke, S Henze, ...
Frontiers in immunology 10, 2572, 2019
Why do proteases mess up with antigen presentation by re-shuffling antigen sequences?
J Liepe, H Ovaa, M Mishto
Current opinion in immunology 52, 81-86, 2018
CD8+ T cells of Listeria monocytogenes‐infected mice recognize both linear and spliced proteasome products
ACM Platteel, M Mishto, K Textoris‐Taube, C Keller, J Liepe, DH Busch, ...
European Journal of Immunology 46 (5), 1109-1118, 2016
Calibrating spatio-temporal models of leukocyte dynamics against in vivo live-imaging data using approximate Bayesian computation
J Liepe, H Taylor, CP Barnes, M Huvet, L Bugeon, T Thorne, JR Lamb, ...
Integrative biology 4 (3), 335-345, 2012
Inference of random walk models to describe leukocyte migration.
PJ Jones, A Sim, HB Taylor, L Bugeon, MJ Dallman, B Pereira, MP Stumpf, ...
Physical Biology, 2015
The T210M substitution in the HLA-a* 02: 01 gp100 epitope strongly affects overall proteasomal cleavage site usage and antigen processing
K Textoris-Taube, C Keller, J Liepe, P Henklein, J Sidney, A Sette, ...
Journal of Biological Chemistry 290 (51), 30417-30428, 2015
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