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Laura Blair
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Accelerated neurodegeneration through chaperone-mediated oligomerization of tau
LJ Blair, BA Nordhues, SE Hill, KM Scaglione, JC O’Leary, SN Fontaine, ...
The Journal of clinical investigation 123 (10), 4158-4169, 2013
3052013
LPS-induced inflammation exacerbates phospho-tau pathology in rTg4510 mice
DC Lee, J Rizer, MLB Selenica, P Reid, C Kraft, A Johnson, L Blair, ...
Journal of neuroinflammation 7, 1-16, 2010
3032010
Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation
JF Abisambra, UK Jinwal, LJ Blair, JC O'Leary, Q Li, S Brady, L Wang, ...
Journal of Neuroscience 33 (22), 9498-9507, 2013
2612013
The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules
UK Jinwal, J Koren, SI Borysov, AB Schmid, JF Abisambra, LJ Blair, ...
Journal of Neuroscience 30 (2), 591-599, 2010
2282010
DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative‐associated proteins
SN Fontaine, D Zheng, JJ Sabbagh, MD Martin, D Chaput, A Darling, ...
The EMBO journal 35 (14), 1537-1549, 2016
2022016
Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden
JC O'Leary, Q Li, P Marinec, LJ Blair, EE Congdon, AG Johnson, ...
Molecular neurodegeneration 5, 1-11, 2010
2002010
Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy
LJ Blair, HD Frauen, B Zhang, BA Nordhues, S Bijan, YC Lin, F Zamudio, ...
Acta neuropathologica communications 3, 1-22, 2015
1642015
Chaperone signalling complexes in Alzheimer's disease
J Koren III, UK Jinwal, DC Lee, JR Jones, CL Shults, AG Johnson, ...
Journal of cellular and molecular medicine 13 (4), 619-630, 2009
1442009
A new anti-depressive strategy for the elderly: ablation of FKBP5/FKBP51
JC O'Leary III, S Dharia, LJ Blair, S Brady, AG Johnson, M Peters, ...
PloS one 6 (9), e24840, 2011
1342011
Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice
JF Abisambra, LJ Blair, SE Hill, JR Jones, C Kraft, J Rogers, J Koren, ...
Journal of Neuroscience 30 (46), 15374-15382, 2010
1332010
Small heat shock proteins, big impact on protein aggregation in neurodegenerative disease
JM Webster, AL Darling, VN Uversky, LJ Blair
Frontiers in pharmacology 10, 462446, 2019
1292019
Allosteric heat shock protein 70 inhibitors rapidly rescue synaptic plasticity deficits by reducing aberrant tau
J Abisambra, UK Jinwal, Y Miyata, J Rogers, L Blair, X Li, SP Seguin, ...
Biological psychiatry 74 (5), 367-374, 2013
1252013
Imbalance of Hsp70 family variants fosters tau accumulation
UK Jinwal, E Akoury, JF Abisambra, JC O'Leary III, AD Thompson, LJ Blair, ...
The FASEB Journal 27 (4), 1450, 2013
1222013
Hsp90 and FKBP51: complex regulators of psychiatric diseases
M Criado-Marrero, T Rein, EB Binder, JT Porter, J Koren III, LJ Blair
Philosophical Transactions of the Royal Society B: Biological Sciences 373 …, 2018
1192018
Targeting Hsp90 and its co-chaperones to treat Alzheimer’s disease
LJ Blair, JJ Sabbagh, CA Dickey
Expert opinion on therapeutic targets 18 (10), 1219-1232, 2014
1112014
Age-associated epigenetic upregulation of the FKBP5 gene selectively impairs stress resiliency
JJ Sabbagh, JC O'Leary III, LJ Blair, T Klengel, BA Nordhues, ...
PloS one 9 (9), e107241, 2014
1102014
The emerging role of peptidyl‐prolyl isomerase chaperones in tau oligomerization, amyloid processing, and Alzheimer's disease
LJ Blair, JD Baker, JJ Sabbagh, CA Dickey
Journal of neurochemistry 133 (1), 1-13, 2015
1092015
Hsp90 activator Aha1 drives production of pathological tau aggregates
LB Shelton, JD Baker, D Zheng, LE Sullivan, PK Solanki, JM Webster, ...
Proceedings of the National Academy of Sciences 114 (36), 9707-9712, 2017
1062017
Hsc70 rapidly engages tau after microtubule destabilization
UK Jinwal, JC O'Leary, SI Borysov, JR Jones, Q Li, J Koren, JF Abisambra, ...
Journal of biological chemistry 285 (22), 16798-16805, 2010
1012010
Facilitating Akt clearance via manipulation of Hsp70 activity and levels
J Koren, UK Jinwal, Y Jin, J O’Leary, JR Jones, AG Johnson, LJ Blair, ...
Journal of biological chemistry 285 (4), 2498-2505, 2010
972010
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Articles 1–20