Laura Blair
Laura Blair
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LPS-induced inflammation exacerbates phospho-tau pathology in rTg4510 mice
DC Lee, J Rizer, MLB Selenica, P Reid, C Kraft, A Johnson, L Blair, ...
Journal of neuroinflammation 7 (1), 1-16, 2010
Accelerated neurodegeneration through chaperone-mediated oligomerization of tau
LJ Blair, BA Nordhues, SE Hill, KM Scaglione, JC O’Leary, SN Fontaine, ...
The Journal of clinical investigation 123 (10), 4158-4169, 2013
Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation
JF Abisambra, UK Jinwal, LJ Blair, JC O'Leary, Q Li, S Brady, L Wang, ...
Journal of Neuroscience 33 (22), 9498-9507, 2013
The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules
UK Jinwal, J Koren, SI Borysov, AB Schmid, JF Abisambra, LJ Blair, ...
Journal of Neuroscience 30 (2), 591-599, 2010
Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden
JC O'Leary, Q Li, P Marinec, LJ Blair, EE Congdon, AG Johnson, ...
Molecular neurodegeneration 5 (1), 1-11, 2010
DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative‐associated proteins
SN Fontaine, D Zheng, JJ Sabbagh, MD Martin, D Chaput, A Darling, ...
The EMBO journal 35 (14), 1537-1549, 2016
Chaperone signalling complexes in Alzheimer's disease
J Koren III, UK Jinwal, DC Lee, JR Jones, CL Shults, AG Johnson, ...
Journal of cellular and molecular medicine 13 (4), 619-630, 2009
Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy
LJ Blair, HD Frauen, B Zhang, BA Nordhues, S Bijan, YC Lin, F Zamudio, ...
Acta neuropathologica communications 3 (1), 1-22, 2015
Allosteric heat shock protein 70 inhibitors rapidly rescue synaptic plasticity deficits by reducing aberrant tau
J Abisambra, UK Jinwal, Y Miyata, J Rogers, L Blair, X Li, SP Seguin, ...
Biological psychiatry 74 (5), 367-374, 2013
Imbalance of Hsp70 family variants fosters tau accumulation
UK Jinwal, E Akoury, JF Abisambra, JC O'Leary III, AD Thompson, LJ Blair, ...
The FASEB Journal 27 (4), 1450-1459, 2013
A new anti-depressive strategy for the elderly: ablation of FKBP5/FKBP51
JC O'Leary III, S Dharia, LJ Blair, S Brady, AG Johnson, M Peters, ...
PloS one 6 (9), e24840, 2011
Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice
JF Abisambra, LJ Blair, SE Hill, JR Jones, C Kraft, J Rogers, J Koren, ...
Journal of Neuroscience 30 (46), 15374-15382, 2010
Facilitating Akt clearance via manipulation of Hsp70 activity and levels
J Koren, UK Jinwal, Y Jin, J O’Leary, JR Jones, AG Johnson, LJ Blair, ...
Journal of biological chemistry 285 (4), 2498-2505, 2010
Hsc70 rapidly engages tau after microtubule destabilization
UK Jinwal, JC O'Leary, SI Borysov, JR Jones, Q Li, J Koren, JF Abisambra, ...
Journal of biological chemistry 285 (22), 16798-16805, 2010
The emerging role of peptidyl‐prolyl isomerase chaperones in tau oligomerization, amyloid processing, and Alzheimer's disease
LJ Blair, JD Baker, JJ Sabbagh, CA Dickey
Journal of neurochemistry 133 (1), 1-13, 2015
Targeting Hsp90 and its co-chaperones to treat Alzheimer’s disease
LJ Blair, JJ Sabbagh, CA Dickey
Expert opinion on therapeutic targets 18 (10), 1219-1232, 2014
Aging analysis reveals slowed tau turnover and enhanced stress response in a mouse model of tauopathy
C Dickey, C Kraft, U Jinwal, J Koren, A Johnson, L Anderson, L Lebson, ...
The American journal of pathology 174 (1), 228, 2009
Age-associated epigenetic upregulation of the FKBP5 gene selectively impairs stress resiliency
JJ Sabbagh, JC O'Leary III, LJ Blair, T Klengel, BA Nordhues, ...
PLoS One 9 (9), e107241, 2014
Hsp90 and FKBP51: complex regulators of psychiatric diseases
M Criado-Marrero, T Rein, EB Binder, JT Porter, J Koren III, LJ Blair
Philosophical Transactions of the Royal Society B: Biological Sciences 373 …, 2018
Glucose-regulated protein 94 triage of mutant myocilin through endoplasmic reticulum-associated degradation subverts a more efficient autophagic clearance mechanism
A Suntharalingam, JF Abisambra, JC O'Leary, J Koren, B Zhang, MK Joe, ...
Journal of Biological Chemistry 287 (48), 40661-40669, 2012
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