| Elucidation of factors responsible for enhanced thermal stability of proteins: a structural genomics based study S Chakravarty, R Varadarajan Biochemistry 41 (25), 8152-8161, 2002 | 296 | 2002 |
| Design of an HA2-based Escherichia coli expressed influenza immunogen that protects mice from pathogenic challenge G Bommakanti, MP Citron, RW Hepler, C Callahan, GJ Heidecker, ... Proceedings of the National Academy of Sciences 107 (31), 13701-13706, 2010 | 262 | 2010 |
| Residue depth: a novel parameter for the analysis of protein structure and stability S Chakravarty, R Varadarajan Structure 7 (7), 723-732, 1999 | 242 | 1999 |
| Elucidation of determinants of protein stability through genome sequence analysis S Chakravarty, R Varadarajan Febs Letters 470 (1), 65-69, 2000 | 228 | 2000 |
| Influenza hemagglutinin stem-fragment immunogen elicits broadly neutralizing antibodies and confers heterologous protection VVA Mallajosyula, M Citron, F Ferrara, X Lu, C Callahan, GJ Heidecker, ... Proceedings of the National Academy of Sciences 111 (25), E2514-E2523, 2014 | 200 | 2014 |
| Depth: a web server to compute depth, cavity sizes, detect potential small-molecule ligand-binding cavities and predict the pKa of ionizable residues in proteins KP Tan, TB Nguyen, S Patel, R Varadarajan, MS Madhusudhan Nucleic acids research 41 (W1), W314-W321, 2013 | 197 | 2013 |
| Effects of buried ionizable amino acids on the reduction potential of recombinant myoglobin R Varadarajan, TE Zewert, HB Gray, SG Boxer Science 243 (4887), 69-72, 1989 | 193 | 1989 |
| Thermodynamics of protein-peptide interactions in the ribonuclease S system studied by titration calorimetry PR Connelly, R Varadarajan, JM Sturtevant, FM Richards Biochemistry 29 (25), 6108-6114, 1990 | 174 | 1990 |
| Cloning, expression in Escherichia coli, and reconstitution of human myoglobin. R Varadarajan, A Szabo, SG Boxer Proceedings of the National Academy of Sciences 82 (17), 5681-5684, 1985 | 161 | 1985 |
| Refinement of the crystal structure of ribonuclease S. Comparison with and between the various ribonuclease A structures EE Kim, R Varadarajan, HW Wyckoff, FM Richards Biochemistry 31 (49), 12304-12314, 1992 | 146 | 1992 |
| Heat capacity changes for protein-peptide interactions in the ribonuclease S system R Varadarajan, PR Connelly, JM Sturtevant, FM Richards Biochemistry 31 (5), 1421-1426, 1992 | 139 | 1992 |
| Stalking influenza by vaccination with pre-fusion headless HA mini-stem SA Valkenburg, VVA Mallajosyula, OTW Li, AWH Chin, G Carnell, ... Scientific reports 6 (1), 22666, 2016 | 137 | 2016 |
| Electrostatic interactions in wild-type and mutant recombinant human myoglobins R Varadarajan, DG Lambright, SG Boxer Biochemistry 28 (9), 3771-3781, 1989 | 132 | 1989 |
| MODIP revisited: re-evaluation and refinement of an automated procedure for modeling of disulfide bonds in proteins VS Dani, C Ramakrishnan, R Varadarajan Protein engineering 16 (3), 187-193, 2003 | 130 | 2003 |
| Thermodynamic characterization of the reversible, two-state unfolding of maltose binding protein, a large two-domain protein C Ganesh, AN Shah, CP Swaminathan, A Surolia, R Varadarajan Biochemistry 36 (16), 5020-5028, 1997 | 130 | 1997 |
| MazF-induced growth inhibition and persister generation in Escherichia coli A Tripathi, PC Dewan, SA Siddique, R Varadarajan Journal of Biological chemistry 289 (7), 4191-4205, 2014 | 123 | 2014 |
| Binding of nucleobases with single-walled carbon nanotubes: Theory and experiment A Das, AK Sood, PK Maiti, M Das, R Varadarajan, CNR Rao Chemical Physics Letters 453 (4-6), 266-273, 2008 | 116 | 2008 |
| A rapid, efficient, and economical inverse polymerase chain reaction-based method for generating a site saturation mutant library PC Jain, R Varadarajan Analytical biochemistry 449, 90-98, 2014 | 114 | 2014 |
| Crystallographic structures of ribonuclease S variants with nonpolar substitution at position 13: packing and cavities R Varadarajan, FM Richards Biochemistry 31 (49), 12315-12327, 1992 | 110 | 1992 |
| Effect of signal peptide on stability and folding of Escherichia coli thioredoxin P Singh, L Sharma, SR Kulothungan, BV Adkar, RS Prajapati, PSS Ali, ... PloS one 8 (5), e63442, 2013 | 109 | 2013 |
